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61.发明授权Magnetic medical devices with changeable magnetic moments and method of navigating magnetic medical devices with changeable magnetic moments 失效具有可变磁矩的磁性医疗设备和导航具有可变磁矩的磁性医疗设备的方法公开(公告)号：US06786219B2
公开(公告)日：2004-09-07
申请号：US10167093
申请日：2002-06-10
IPC分类号： A61B1900
CPC分类号： A61B17/3421 , A61B1/00158 , A61B34/73 , A61B90/36 , A61B2018/00023 , A61M25/0127
摘要： A method of navigating a medical device having a changeable magnetic moment within an operating region within a patient, the method includes applying a navigating magnetic field to the operating region with an external source magnet, and changing the direction of the magnetic moment in the medical device to change the orientation of the medical device in a selected direction within the operating region. The magnet moment of the medical device can be created by one or more electromagnet coils, in which case the magnetic moment can be changed by changing the current to the coil. Alternatively, the magnetic moment of the medical device can be created by one or more permanent magnets, in which case the magnetic moment can be changed by mechanically or magnetically manipulating the permanent magnet.
摘要翻译： 一种在患者体内的操作区域内导航具有可变磁矩的医疗装置的方法，所述方法包括：利用外部源磁体对操作区域施加导航磁场，并改变医疗装置中的磁矩方向 以在操作区域内沿所选择的方向改变医疗装置的方向。 医疗装置的磁矩可以由一个或多个电磁线圈产生，在这种情况下，可以通过改变线圈的电流来改变磁矩。 或者，医疗装置的磁矩可以由一个或多个永磁体产生，在这种情况下，可以通过机械或磁力操纵永久磁铁来改变磁矩。
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62.发明授权公开(公告)号：US06755816B2
公开(公告)日：2004-06-29
申请号：US10460710
申请日：2003-06-12
申请人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
发明人： Rogers C. Ritter , Bevil J. Hogg , Peter R. Werp , Walter M. Blume , Francis M. Creighton, IV , Roger N. Hastings
IPC分类号： A61B1700
CPC分类号： A61B1/00158 , A61B1/01 , A61B17/12022 , A61B17/12113 , A61B17/12131 , A61B34/70 , A61B34/73 , A61B2017/00876 , A61B2017/1205 , A61B2034/733 , A61M25/0105 , A61M25/0127
摘要： A method of turning a medical device, having a magnetically responsive element associated with its distal end, at an operating point within an operating region inside a patient's body from an initial direction to a desired final direction, through the movement of at least one external source magnet. The at least one external source magnet is moved in such a way as to change the direction of the distal end of the magnetic medical device from the initial direction to the desired final direction without substantial deviation from the plane containing the initial direction and the desired final direction.
摘要翻译： 一种通过至少一个外部源的移动来将具有与其远端相关联的具有磁响应元件的医疗装置转动到患者身体内部的操作区域内的操作区域的方法，所述操作区域从初始方向到期望的最终方向 磁铁。 至少一个外部源磁体以使得磁性医疗装置的远端的方向从初始方向改变到期望的最终方向的方式移动，而不会从包含初始方向的平面和期望的最终方向显着偏离 方向。
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公开(公告)号：US06575168B2
公开(公告)日：2003-06-10
申请号：US09759996
申请日：2001-01-12
申请人： Daniel M. LaFontaine , Kent D. Harrison , Charles L. Euteneuer , Roger N. Hastings , Lixiao Wang
发明人： Daniel M. LaFontaine , Kent D. Harrison , Charles L. Euteneuer , Roger N. Hastings , Lixiao Wang
IPC分类号： A61B1900
CPC分类号： A61F2/82 , A61B17/32053 , A61B2017/00243 , A61B2017/00252 , A61B2017/1135 , A61B2017/306 , A61B2090/3929 , A61B2090/3945 , A61B2090/3958 , A61F2/06 , A61F2/064 , A61F2/90 , A61F2/958 , A61F2250/0098 , Y10S623/902
摘要： A percutaneous system for bypassing a restriction in a native vessel of a mammal having an aorta includes providing a graft having a body portion with a first end, a second end and a lumen therebetween. An aperture is formed in the aorta. The graft is inserted into the aorta and the first end of the graft is connected to the aorta about the aperture in the aorta. An aperture is then formed in the native vessel distal of the restriction. The second end of the graft is connected to the native vessel about the aperture therein such that the lumen in the graft communicates with the aorta and the native vessel.
摘要翻译： 用于绕过具有主动脉的哺乳动物的天然血管中的限制的经皮系统包括提供具有主体部分的移植物，其具有第一端，第二端和其间的内腔。 在主动脉中形成孔。 将移植物插入主动脉，并且移植物的第一端围绕主动脉的孔连接到主动脉。 然后在限制器的远端的天然血管中形成孔。 移植物的第二端围绕其中的孔连接到天然血管，使得移植物中的内腔与主动脉和天然血管连通。
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64.发明授权公开(公告)号：US06542766B2
公开(公告)日：2003-04-01
申请号：US09909188
申请日：2001-07-19
IPC分类号： A61B5042
CPC分类号： A61M25/0127 , A61B17/22 , A61B18/02 , A61B18/1492 , A61B34/20 , A61B34/73 , A61B90/39 , A61B2017/00243 , A61B2017/00247 , A61B2017/003 , A61B2017/00345 , A61B2018/00392 , A61B2018/0212 , A61B2034/2051 , A61B2090/3954 , A61M2025/0166 , A61N7/022
摘要： A method of applying an elongate magnetic element to the surface of an internal body structure includes applying a magnetic field to the elongate magnetic element to orient the elongate magnetic element in a selected orientation; and applying a magnetic gradient to the elongate magnetic element to draw the elongate magnetic element against the surface of the body structure.
摘要翻译： 将细长磁性元件施加到内部主体结构的表面的方法包括将磁场施加到细长磁性元件以将细长磁性元件定向成选定的取向; 以及向所述细长磁性元件施加磁梯度以将所述细长磁性元件拉过所述主体结构的表面。
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65.发明授权Magnet assembly with variable field directions and methods of magnetically navigating medical objects 失效具有可变磁场方向的磁体组件和磁性导航医疗物体的方法公开(公告)号：US06537196B1
公开(公告)日：2003-03-25
申请号：US09695119
申请日：2000-10-24
IPC分类号： A61N200
CPC分类号： A61B1/00158 , A61B17/00234 , A61B34/70 , A61B34/73 , A61B2034/732
摘要： An adjustable field magnet assembly comprising at least two magnets rotatably mounted so that the rotation of at least one of the at least two rotatably mounted magnets changes the magnetic field projected by magnet assembly. The magnet is particularly useful in providing a magnet field of variable direction for use in magnetically navigating medical objects in the body by rotating the magnets comprising the assembly and/or rotating the entire assembly.
摘要翻译： 一种可调磁场组件，包括至少两个可旋转地安装的磁体，使得至少两个可旋转地安装的磁体中的至少一个的旋转改变由磁体组件投射的磁场。 磁体特别可用于通过旋转包括组件的磁体和/或旋转整个组件来提供可变方向的磁场，用于磁体导航身体中的医疗物体。
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公开(公告)号：US06364823B1
公开(公告)日：2002-04-02
申请号：US09527108
申请日：2000-03-16
IPC分类号： A61M3700
CPC分类号： A61N2/02 , A61B17/12022 , A61B17/12113 , A61B17/1214 , A61B17/12186 , A61B2017/00876 , A61B2017/12086 , A61L24/001 , A61L24/02 , A61L24/046 , A61L24/06 , A61L24/08 , A61L24/106 , A61L24/108 , A61L31/022 , A61L31/18 , A61L2430/36 , C08L35/04 , C08L1/12
摘要： Embolic compositions for treating vascular defects such as aneurysms include a mixture of a biocompatible polymer material, a biocompatible solvent, and preferably also an adhesive. The compositions preferably further comprise magnetic particles for controlling the delivery of the embolic agent. These magnetic particles preferably lose magnet strength over time, so that they do not interfere with subsequent magnetic diagnostic and therapeutic procedures. The compositions preferably also include radiopaque particles, which may be the magnetic particles, to facilitate imaging the embolic material.
摘要翻译： 用于治疗血管缺陷如动脉瘤的栓塞组合物包括生物相容性聚合物材料，生物相容性溶剂以及优选粘合剂的混合物。 组合物优选还包含用于控制栓塞剂递送的磁性颗粒。 这些磁性粒子优选随着时间而丧失磁体强度，使得它们不会干扰随后的磁诊断和治疗过程。 组合物优选还包括不透射线的颗粒，其可以是磁性颗粒，以便于栓塞材料的成像。
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公开(公告)号：US06203508B1
公开(公告)日：2001-03-20
申请号：US08951769
申请日：1997-10-16
申请人： Brooke Q. Ren , Roger N. Hastings
发明人： Brooke Q. Ren , Roger N. Hastings
IPC分类号： A61B503
CPC分类号： A61B5/1076 , A61M25/10
摘要： The inventive method requires advancing a three-dimensional imaging balloon catheter to the site of a lesion to be imaged, inflating or molding the balloon to image the lesion, deflating the balloon, withdrawing the catheter from the body lumen and re-inflating the balloon which reassumes its memorized shape. Stress and thermal mapping of the balloon is then done by direct observation or by numerical analysis of the material strain and color of the re-inflated 3D imaging balloon.
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公开(公告)号：US6117065A
公开(公告)日：2000-09-12
申请号：US103595
申请日：1998-06-24
CPC分类号： A61N5/1002 , A61M2025/0063 , A61N2005/1003 , A61N2005/1004
摘要： A device for irradiating human vessel interior walls including a perfusion balloon catheter having a radioactive perfusion tube affixed therein. Preferably, the balloon is helical, having adjacent helical strand windings closely spaced in contact upon inflation to minimize trapped blood and reduce attenuation. The perfusion tube can be made radioactive by inclusion of a helical, radioactive metal coil in the perfusion tube wall. In use, the catheter can be advanced over a guide wire to a stenosis, inflated to dilate the site, with beta radiation from the coil passing through the device to the vessel walls, relatively unhindered by blood.
摘要翻译： 一种用于照射人体血管内壁的装置，包括具有固定在其中的放射性灌注管的灌注球囊导管。 优选地，气囊是螺旋形的，其具有在充气时紧密间隔开的相邻螺旋线圈绕组以最小化被捕获的血液并减少衰减。 灌注管可以通过在灌注管壁中包含螺旋放射性金属线圈而被制成放射性。 在使用中，导管可以在导丝上前进到狭窄，充气以扩张部位，来自线圈的β辐射通过装置到血管壁，相对不受血液阻碍。
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公开(公告)号：US5860938A
公开(公告)日：1999-01-19
申请号：US707829
申请日：1996-09-06
IPC分类号： A61B5/0215 , A61B5/021
CPC分类号： A61B5/6851 , A61B5/0215 , A61B5/02158 , A61M25/09 , A61M2025/09175
摘要： A guide wire that is capable of sensing the phasic pressure at the distal end of the guide wire. The guide wire has a central lumen which provides a non-compliant fluid path from the distal end of the guide wire to a pressure transducer at the proximal end of the guide wire.
摘要翻译： 能够感测导丝末端的相位压力的导丝。 引导线具有中心腔，其提供从导丝的远端到导丝近端处的压力传感器的不顺从的流体路径。
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公开(公告)号：US5855546A
公开(公告)日：1999-01-05
申请号：US868482
申请日：1997-06-03
CPC分类号： A61M25/0127 , A61M25/1002 , A61N5/1002 , A61M2025/0177 , A61M2025/1047 , A61M2025/105 , A61M2025/1095 , A61N2005/1003
摘要： A catheter capable of irradiating blood vessel walls to inhibit restenosis after angioplasty. Catheters are capable of simultaneous irradiation, angioplasty, and in some devices, drug infusion. Preferred catheters include a helical perfusion balloon having strand windings spaced apart when inflated and defining a perfusion lumen within. A tubular sheath over the helical strands and distal shaft region is used in some embodiments and defines an outer wall for the perfusion lumen. A spiral, inter-strand space is defined between the sheath outer wall and the blood vessel inner wall, providing a confined volume for controlled delivery of drugs to the vessel wall in conjunction with irradiation. A device having a radiation wire, distally closed-end tube is provided. A device having a radiation wire open ended tube terminating proximally of the perfusion lumen is also provided.
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