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公开(公告)号:US5948439A
公开(公告)日:1999-09-07
申请号:US962118
申请日:1997-10-31
申请人: Yochanan Forman , Orna Levin , Doron Friedman , Michael Friedman
发明人: Yochanan Forman , Orna Levin , Doron Friedman , Michael Friedman
CPC分类号: A61K9/0007
摘要: An effervescent granule for the release and efficient dispersion of a herbal preparation in water. Also provided is a method of making the phytomedicated granule and a method of using the granule. The granule of the present invention is particularly efficient for the dispersion of a herbal preparation which includes an essential oil, although herbal preparations including an herbal extract can also be used.
摘要翻译: 一种泡腾颗粒,用于释放和有效地将草药制剂分散在水中。 还提供了制备植物化颗粒的方法和使用该颗粒的方法。 本发明的颗粒对于包含精油的草药制剂的分散特别有效,尽管也可以使用包括草药提取物的草药制剂。
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公开(公告)号:US5908704A
公开(公告)日:1999-06-01
申请号:US886030
申请日:1997-06-30
CPC分类号: B32B17/10 , B32B17/06 , B32B17/10036 , B32B17/10366 , B32B17/1055 , C08L27/18 , C08L2205/02 , C08L27/00 , Y10S428/913 , Y10T156/1007 , Y10T156/1008 , Y10T428/131 , Y10T428/1314 , Y10T428/24777 , Y10T428/24868 , Y10T428/26 , Y10T428/2964 , Y10T428/315 , Y10T428/31507 , Y10T428/3154 , Y10T428/31649
摘要: Optical and firescreening protective glazing laminates comprising fluoropolymer interlayer films are described. The films and their laminates comprise THV and blends of THV with FEP, ECTFE or ECCTFE, and modified with additives, such as coupling agents, pigment or color concentrates, and IR- or UV- light blockers, and may be subjected to a surface corona treatment. The films also may incorporate a fiber mesh for additional reinforcement.
摘要翻译: 描述了包含氟聚合物中间膜的光学和防火防护玻璃层压板。 薄膜及其层压板包括THV和THV与FEP,ECTFE或ECCTFE的混合物,并用添加剂如偶联剂,颜料或颜色浓缩物和IR-或UV-光阻挡剂进行改性,并且可以经受表面电晕 治疗。 这些薄膜还可以加入纤维网以进一步加固。
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公开(公告)号:US5792560A
公开(公告)日:1998-08-11
申请号:US535413
申请日:1995-09-28
申请人: Michael Friedman , Louis Laucirica
发明人: Michael Friedman , Louis Laucirica
CPC分类号: C08J5/18 , B32B17/10036 , B32B17/10587 , B32B17/10678 , B32B17/10788 , B32B27/08 , B32B27/32 , B32B7/12 , C08J2323/08 , Y10T428/31645
摘要: High clarity optical and safety glass laminate interlayer films and optical laminates are described. The films and their laminates comprise very low density polyethylene and/or its copolymers, preferably polymerized with metallocene catalysts, and modified with additives, such as coupling agents, clarifying or nucleation agents, UV-light absorbers, pigment or color concentrate, and IR-light blockers.
摘要翻译: 描述了高透明度的光学和安全玻璃层压体层间膜和光学层压板。 薄膜及其层压体包含非常低密度的聚乙烯和/或其共聚物,优选用茂金属催化剂聚合,并用添加剂如偶联剂,澄清或成核剂,UV-光吸收剂,颜料或着色浓缩物和IR- 阻光剂。
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公开(公告)号:US5648399A
公开(公告)日:1997-07-15
申请号:US428825
申请日:1995-04-25
申请人: Michael Friedman , Amnon Sintov
发明人: Michael Friedman , Amnon Sintov
CPC分类号: A61K6/0017 , A61K6/0032 , A61K6/0058 , A61K6/0067 , A61K9/006 , A61K9/0063 , Y10S514/887 , Y10S514/90 , Y10S514/902
摘要: The invention relates to methods for the treatment of gingivitis, oral plaque and oral or dermatological fungal infections by the administration of a liquid methacrylic acid copolymer composition that contains a release adjusting agent and a pharmacological agent. The composition forms a solid film upon drying, and is capable of accomplishing the sustained release of the pharmacological agent such as to permit its use in the treatment or prevention of dental or dermatological conditions.
摘要翻译: 本发明涉及通过施用含有释放调节剂和药理学剂的液体甲基丙烯酸共聚物组合物来治疗牙龈炎,口腔菌斑和口腔或皮肤病学真菌感染的方法。 该组合物在干燥时形成固体膜,并且能够实现药物剂的持续释放,例如允许其用于治疗或预防牙齿或皮肤病学条件。
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公开(公告)号:US5438076A
公开(公告)日:1995-08-01
申请号:US2481
申请日:1993-01-04
申请人: Michael Friedman , Amnon Sintov
发明人: Michael Friedman , Amnon Sintov
CPC分类号: A61K6/0017 , A61K6/0032 , A61K6/0058 , A61K6/0067 , A61K9/006 , A61K9/0063 , Y10S514/887 , Y10S514/90 , Y10S514/902
摘要: The invention relates methods for the treatment of gingivitis, oral plaque and oral or dermatological fungal infections by the administration of a liquid methacrylic acid copolymer composition that contains a release adjusting agent and a pharmacological agent. The composition forms a solid film upon drying, and is capable of accomplishing the sustained release of the pharmacological agent such as to permit its use in the treatment or prevention of dental or dermatological conditions.
摘要翻译: 本发明涉及通过施用含有释放调节剂和药理学试剂的液体甲基丙烯酸共聚物组合物来治疗牙龈炎,口腔斑块和口腔或皮肤病学真菌感染的方法。 该组合物在干燥时形成固体膜,并且能够实现药物剂的持续释放,例如允许其用于治疗或预防牙齿或皮肤病学条件。
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公开(公告)号:US5139768A
公开(公告)日:1992-08-18
申请号:US662985
申请日:1991-02-28
申请人: Michael Friedman
发明人: Michael Friedman
CPC分类号: A61K6/0067 , A61K6/0017 , Y10S514/90 , Y10S514/902
摘要: The invention relates to an oral composition for the treatment and prevention of dental hypersensitivity comprising an anti-hypersensitivity agent embedded in a sustained release carrier such as a cellulosic or hydrophobic polymer, and a method for the use of said composition in treating and preventing dental hypersensitivity. The invention also provides for the supplementation of said oral composition with an adhesive and a plasticizer to increase the effectiveness of the anti-hypersensitivity agent.
摘要翻译: 本发明涉及一种用于治疗和预防牙齿超敏反应的口腔用组合物,其包含嵌入缓释载体(例如纤维素或疏水性聚合物)中的抗超敏反应剂,以及所述组合物在治疗和预防牙齿超敏反应中的用途 。 本发明还提供了用粘合剂和增塑剂补充所述口腔组合物以增加抗超敏剂的有效性。
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公开(公告)号:US5116603A
公开(公告)日:1992-05-26
申请号:US465786
申请日:1990-01-18
申请人: Michael Friedman
发明人: Michael Friedman
IPC分类号: A61K9/70 , A61K6/00 , A61K8/00 , A61K8/34 , A61K8/73 , A61K8/86 , A61K8/88 , A61K8/89 , A61K8/891 , A61K9/00 , A61K31/415 , A61K31/70 , A61K45/08 , A61P31/04 , A61P31/10 , A61Q11/00 , C08F10/02 , C08F20/18 , C08L77/00
CPC分类号: A61K6/0017 , A61K31/415 , A61K31/7048 , A61K6/0067 , A61K9/0063 , Y10S514/90 , Y10S514/901 , Y10S514/902 , Y10S514/934 , Y10S514/937
摘要: The invention relates to an oral composition for prevention of mycotic infections of the oral cavity comprising an antifungal compound embedded in a sustained release carrier such as a cellulosic polymer or a hydrophobic polymer, and a method for use of said composition in preventing microfungal infections in the oral cavity. The invention also provides for the supplementation of said oral composition with an adhesive and a plasticizer to increase antifungal effectiveness.
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公开(公告)号:US5023082A
公开(公告)日:1991-06-11
申请号:US175623
申请日:1988-03-30
IPC分类号: A61K47/30 , A61K20060101 , A61K9/00 , A61K9/20 , A61K9/22 , A61K9/70 , A61K47/00 , A61K47/42 , A61P1/02
CPC分类号: A61K9/0063 , A61K9/2063 , A61K9/7007
摘要: The present invention pertains to biodegradable sustained-release composins capable of achieving the sustained release of a pharmaceutical or other agent. The compositions can be formed into implant devices which may be used to treat a wide variety of diseases and conditions. The implants are especially useful in treating diseases such as periodontal disease which require prolonged drug release.
摘要翻译: 本发明涉及能够实现药物或其它试剂持续释放的可生物降解的缓释组合物。 组合物可以形成植入装置,其可以用于治疗各种各样的疾病和病症。 植入物特别可用于治疗需要延长药物释放的牙周病等疾病。
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公开(公告)号:US3987603A
公开(公告)日:1976-10-26
申请号:US603012
申请日:1975-08-08
CPC分类号: B65B43/123 , B65B25/20 , B65B57/04 , Y10T225/16
摘要: Bags from a roll of polyethylene bags are fed through a braking device and thence past spreading devices and a floating hook support, whereupon are engaged sequentially the hooks of hangers upon which garments or the like are supported. The bags are provided with indicia which are detected by a detecting device to actuate the braking device so that the bags may be readily torn off before they seat on the respective garments being packaged. Provision is made for adjustments of the braking time so that the brake automatically releases after a fixed period of time thereby facilitating a drawing of the bags from the source for sequential bagging operations.
摘要翻译: 来自一卷聚乙烯袋的袋子通过制动装置进料,然后通过铺展装置和浮钩支撑件,随后依次接合衣架等的支撑钩。 这些袋子设置有由检测装置检测到的致动制动装置的标记,使得袋子可以在它们坐在被包装的各个衣服上之前容易地撕开。 作出了对制动时间的调整的规定,使得制动器在一段固定的时间段之后自动释放,从而便于从源头抽出袋以进行顺序装袋操作。
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公开(公告)号:US09150592B2
公开(公告)日:2015-10-06
申请号:US14135793
申请日:2013-12-20
申请人: Kevin P. Cusack , Thomas D. Gordon , Michael Z. Hoemann , David C. Ihle , Bin Li , Gloria Y. Lo Schiavo , Gagandeep K. Somal , Michael Friedman , Martin E. Hayes , Wouter Iwema Bakker
发明人: Kevin P. Cusack , Thomas D. Gordon , Michael Z. Hoemann , David C. Ihle , Bin Li , Gloria Y. Lo Schiavo , Gagandeep K. Somal , Michael Friedman , Martin E. Hayes , Wouter Iwema Bakker
IPC分类号: A61K31/44 , C07D401/14 , C07D513/04 , C07D401/04 , C07D487/04 , C07D513/20 , C07D513/10
CPC分类号: C07D513/04 , C07D401/04 , C07D401/14 , C07D487/04 , C07D513/10 , C07D513/20
摘要: The invention provides a compound of Formula (I) pharmaceutically acceptable salts, pro-drugs, biologically active metabolites, stereoisomers and isomers thereof wherein the variable are defined herein. The compounds of the invention are useful for treating immunological and oncological conditions.
摘要翻译: 本发明提供式(I)化合物的药学上可接受的盐,前药,生物活性代谢物,立体异构体和异构体,其中变量在本文中定义。 本发明的化合物可用于治疗免疫学和肿瘤学病症。
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