公开(公告)号：US07023611B2

公开(公告)日：2006-04-04

申请号：US10077617

申请日：2002-02-15

申请人： Tizhi Huang ,  Ming Xu ,  Chongchang Mao ,  Tiejun Xia ,  Wei Feng

发明人： Tizhi Huang ,  Ming Xu ,  Chongchang Mao ,  Tiejun Xia ,  Wei Feng

IPC分类号： H04B10/12

CPC分类号： H04B10/2941 ,  H04B10/0731

摘要： Devices and methods for equalizing the gain of an optical amplifier are described. For devices including harmonic filters that are controllable by amplitude control voltages and phase control voltages, techniques for controlling the amplitude control voltages and phase control voltages are presented. Additionally, device architectures are described by which an incoming optical signal is equalized to compensate for uneven gain in prior amplifiers or other optical components, and in which the incoming optical signal is received at a beam displacer and separated into orthogonal component beams, wherein the beams are counter-propagated through the equalizer in opposite directions through the same spatial path so as to minimize or eliminate the effects spatially dependent imperfections in the equalizer.

公开(公告)号：US09562051B2

公开(公告)日：2017-02-07

申请号：US13255081

申请日：2010-03-05

申请人： Edmond J. LaVoie ,  Wei Feng ,  Leroy F. Liu

发明人： Edmond J. LaVoie ,  Wei Feng ,  Leroy F. Liu

IPC分类号： C07D491/04 ,  A61K31/4355

CPC分类号： C07D491/04 ,  A61K31/4355

摘要： The invention provides compounds of formula I: wherein A, B, X, and Y have any of the values defined in the specification, as well as pharmaceutical compositions comprising such compounds, processes for preparing such compounds, and therapeutic methods for treating cancer and other topoisomerase mediated conditions.

摘要翻译： 本发明提供了式I化合物：其中A，B，X和Y具有说明书中定义的任何值，以及包含这些化合物的药物组合物，制备这些化合物的方法，以及用于治疗癌症等的治疗方法 拓扑异构酶介导的条件。

公开(公告)号：US20160158288A1

公开(公告)日：2016-06-09

申请号：US14903548

申请日：2014-07-14

申请人： Daohong ZHOU ,  Yi LUO ,  Lijian SHAO ,  Wei FENG ,  Jianhui CHANG ,  THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS

发明人： Daohong Zhou ,  Yi Luo ,  Lijian Shao ,  Wei Feng ,  Jianhui Chang

IPC分类号： A61K35/28 ,  C12N5/0789

CPC分类号： A61K35/28 ,  A61K35/15 ,  A61K2035/124 ,  C12N5/0647 ,  C12N2501/2304 ,  C12N2502/1157 ,  A61K2300/00

摘要： The invention generally features compositions and methods for expanding long term hematopoietic stem cells (HSCs) in a population of cells. In particular, the invention relates to a method of expanding long term HSCs by culturing an initial population of HSCs with macrophages that promote self-renewal of long term HSCs. The expanded cell population provides a source of cells for therapeutic treatments utilizing HSC transplantation.

摘要翻译： 本发明一般具有在细胞群中扩展长期造血干细胞（HSCs）的组合物和方法。 特别地，本发明涉及通过培养具有促进长期HSC的自我更新的巨噬细胞的初始HSC群体来扩展长期HSC的方法。 扩大的细胞群体提供了使用HSC移植治疗治疗的细胞来源。

公开(公告)号：US09209103B2

公开(公告)日：2015-12-08

申请号：US13187266

申请日：2011-07-20

申请人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

发明人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

IPC分类号： H01M10/46 ,  H02J7/00 ,  H01L23/34 ,  H01M10/615 ,  H01M10/625 ,  H01M10/657 ,  H01M10/6571 ,  H01M10/651 ,  H01M10/6572 ,  H02M3/158

CPC分类号： H01L23/345 ,  H01L2924/0002 ,  H01M10/615 ,  H01M10/625 ,  H01M10/651 ,  H01M10/657 ,  H01M10/6571 ,  H01M10/6572 ,  H02J7/0014 ,  H02J7/0054 ,  H02J7/0075 ,  H02J7/0091 ,  H02J7/0093 ,  H02M3/158 ,  Y02E60/12 ,  Y02T10/7055 ,  H01L2924/00

摘要： A circuit for heating a battery includes the battery including parasitic damping and current storage components, a switch unit, a switching control component coupled to the switch unit, a charge storage component, and a current limiting circuit. The damping component, current storage component, switch unit, and charge storage component are connected. The switching control component is configured to turn on and off the switch unit so as to control a first current flowing from the battery to the first charge storage component and a second current flowing from the first charge storage component to the battery. The current limiting circuit is configured to limit the second current flowing from the charge storage component to the battery. The circuit for heating the battery is configured to heat the battery by at least discharging and charging the battery.

摘要翻译： 用于加热电池的电路包括包括寄生阻尼和电流存储部件的电池，开关单元，耦合到开关单元的开关控制部件，电荷存储部件和限流电路。 阻尼部件，电流存储部件，开关单元和电荷存储部件被连接。 开关控制部件被配置为打开和关闭开关单元，以便控制从电池流向第一电荷存储部件的第一电流和从第一电荷存储部件流向电池的第二电流。 电流限制电路被配置为限制从电荷存储部件流向电池的第二电流。 用于加热电池的电路被配置为通过至少对电池进行放电和充电来加热电池。

公开(公告)号：US09120394B2

公开(公告)日：2015-09-01

申请号：US13465906

申请日：2012-05-07

申请人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma ,  Xianyin Li

发明人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma ,  Xianyin Li

IPC分类号： H02J7/00 ,  B60L11/18 ,  H01M10/44 ,  H01M10/625 ,  H01M10/63 ,  H01M10/615 ,  H01M10/633 ,  H01M10/657 ,  H01M10/6571 ,  H02M3/158

CPC分类号： B60L11/1875 ,  H01M10/443 ,  H01M10/615 ,  H01M10/625 ,  H01M10/63 ,  H01M10/633 ,  H01M10/657 ,  H01M10/6571 ,  H02M3/158 ,  Y02T10/7005 ,  Y02T10/705

摘要： Certain embodiments of the present invention provide a battery heating circuit, comprising a plurality of switch units 1, a switching control module 100, a damping component R1, an energy storage circuit, and a polarity inversion unit 101, wherein: the energy storage circuit is connected with the battery, and comprises a current storage component L1 and a plurality of charge storage components C1; the plurality of charge storage components C1 are connected with the plurality of switch units 1 in series in one-to-one correspondence to form a plurality of branches; the plurality of branches is connected in parallel with each other and then connected with the current storage component L1 and damping component R1 in series; the switching control module 100 is connected with the switch units 1, and is configured to control ON/OFF of the switch units 1.

摘要翻译： 本发明的某些实施例提供了一种电池加热电路，包括多个开关单元1，开关控制模块100，阻尼组件R1，能量存储电路和极性反转单元101，其中：能量存储电路 与电池连接，并且包括电流存储部件L1和多个电荷存储部件C1; 多个电荷存储组件C1与多个开关单元1一一对应地串联连接以形成多个分支; 多个分支彼此并联连接，然后与当前存储部件L1和阻尼部件R1串联连接; 切换控制模块100与开关单元1连接，并且被配置为控制开关单元1的接通/断开。

公开(公告)号：US09093413B2

公开(公告)日：2015-07-28

申请号：US13184894

申请日：2011-07-18

申请人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

发明人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

IPC分类号： H02J7/00 ,  H01L23/34 ,  H01M10/615 ,  H01M10/625 ,  H01M10/657 ,  H01M10/6571 ,  H02M3/158

CPC分类号： H01L23/345 ,  H01L2924/0002 ,  H01M10/615 ,  H01M10/625 ,  H01M10/651 ,  H01M10/657 ,  H01M10/6571 ,  H01M10/6572 ,  H02J7/0014 ,  H02J7/0054 ,  H02J7/0075 ,  H02J7/0091 ,  H02J7/0093 ,  H02M3/158 ,  Y02E60/12 ,  Y02T10/7055 ,  H01L2924/00

摘要： Under one aspect, a circuit for heating a battery includes the battery including a parasitic damping component and a parasitic current storage component, a switch unit, a switching control component coupled to the switch unit, and a charge storage component. The charge storage and current storage components are at least parts of an energy storage circuit. The damping component, the current storage component, the switch unit, and the charge storage component are connected to form at least a part of a loop. The switching control component is configured to turn on and off the switch unit so as to control a current flowing from the battery to the charge storage component and flowing from the charge storage component to the battery. The circuit for heating the battery is configured to heat the battery by at least discharging and charging the battery.

摘要翻译： 在一个方面，一种用于加热电池的电路包括包括寄生阻尼分量和寄生电流存储组件的电池，开关单元，耦合到开关单元的开关控制组件和电荷存储组件。 电荷存储和电流存储部件至少是能量存储电路的一部分。 阻尼部件，电流存储部件，开关单元和电荷存储部件被连接以形成环路的至少一部分。 开关控制部件被配置为打开和关闭开关单元，以便控制从电池流向电荷存储部件并从电荷存储部件流向电池的电流。 用于加热电池的电路被配置为通过至少对电池进行放电和充电来加热电池。

公开(公告)号：US09087806B2

公开(公告)日：2015-07-21

申请号：US13185756

申请日：2011-07-19

申请人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

发明人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

IPC分类号： H02J7/00 ,  H01L23/34 ,  H01M10/615 ,  H01M10/625 ,  H01M10/657 ,  H01M10/6571 ,  H02M3/158

CPC分类号： H01L23/345 ,  H01L2924/0002 ,  H01M10/615 ,  H01M10/625 ,  H01M10/651 ,  H01M10/657 ,  H01M10/6571 ,  H01M10/6572 ,  H02J7/0014 ,  H02J7/0054 ,  H02J7/0075 ,  H02J7/0091 ,  H02J7/0093 ,  H02M3/158 ,  Y02E60/12 ,  Y02T10/7055 ,  H01L2924/00

摘要： Under one aspect, a heating circuit for at least a first battery and a second battery includes a first charging/discharging circuit, which is connected to the first battery, and a second charging/discharging circuit, which is connected to the second battery. The first charging/discharging circuit includes a first damping component, a first current storage component, a first switch unit, and a charge storage component, all of which are connected in a first loop with each other. The second charging/discharging circuit includes a second damping component, a second current storage component, a second switch unit, and the charge storage component, all of which are connected in a second loop with each other.

摘要翻译： 在一个方面，用于至少第一电池和第二电池的加热电路包括连接到第一电池的第一充电/放电电路和连接到第二电池的第二充电/放电电路。 第一充电/放电电路包括第一阻尼部件，第一电流存储部件，第一开关单元和电荷存储部件，它们都以第一回路彼此连接。 第二充电/放电电路包括第二阻尼部件，第二电流存储部件，第二开关单元和电荷存储部件，它们都以第二回路彼此连接。

公开(公告)号：US08941357B2

公开(公告)日：2015-01-27

申请号：US13184906

申请日：2011-07-18

申请人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

发明人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

IPC分类号： H01M10/46 ,  H02J7/00 ,  H01L23/34 ,  H01M10/615 ,  H01M10/625 ,  H01M10/657 ,  H01M10/6571 ,  H02M3/158

CPC分类号： H01L23/345 ,  H01L2924/0002 ,  H01M10/615 ,  H01M10/625 ,  H01M10/651 ,  H01M10/657 ,  H01M10/6571 ,  H01M10/6572 ,  H02J7/0014 ,  H02J7/0054 ,  H02J7/0075 ,  H02J7/0091 ,  H02J7/0093 ,  H02M3/158 ,  Y02E60/12 ,  Y02T10/7055 ,  H01L2924/00

摘要： A circuit for heating a battery includes a switch unit, switching control module, damping component, energy storage circuit, and freewheeling circuit. The energy storage circuit is connected with the battery, and includes a current storage component and charge storage component. The damping component, switch unit, current storage component, and charge storage component are connected in series. The switching control module is connected with the switch unit, and is configured to control switching on and off of the switch unit so that current can flow back-and-forth between the battery and energy storage circuit when the switch unit switches on, and amplitude of the current flowing from the energy storage circuit to the battery can be controlled. The freewheeling circuit is configured to sustain the current flowing to the battery when there is current flowing from the energy storage circuit to the battery and after the switch unit switches off.

摘要翻译： 用于加热电池的电路包括开关单元，开关控制模块，阻尼部件，能量存储电路和续流电路。 能量存储电路与电池连接，并且包括电流存储部件和电荷存储部件。 阻尼部件，开关单元，电流存储部件和电荷存储部件串联连接。 开关控制模块与开关单元连接，并且被配置为控制开关单元的接通和关断，使得当开关单元接通时电流可以在电池和能量存储电路之间前后流动，并且振幅 可以控制从能量存储电路流向电池的电流。 续流电路被配置为当电流从能量存储电路流向电池并且在开关单元断开之后，维持流向电池的电流。

公开(公告)号：US08941356B2

公开(公告)日：2015-01-27

申请号：US13168014

申请日：2011-06-24

申请人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

发明人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Shibin Ma

IPC分类号： H01M10/46 ,  H02J7/00 ,  H01L23/34 ,  H01M10/615 ,  H01M10/625 ,  H01M10/657 ,  H01M10/6571 ,  H02M3/158

CPC分类号： H01L23/345 ,  H01L2924/0002 ,  H01M10/615 ,  H01M10/625 ,  H01M10/651 ,  H01M10/657 ,  H01M10/6571 ,  H01M10/6572 ,  H02J7/0014 ,  H02J7/0054 ,  H02J7/0075 ,  H02J7/0091 ,  H02J7/0093 ,  H02M3/158 ,  Y02E60/12 ,  Y02T10/7055 ,  H01L2924/00

摘要： Circuit and method for heating a battery. The circuit includes the battery including a first damping component and a first current storage component, a switch unit, a switching control component, a first charge storage component, and an energy transfer unit. The switching control component is configured to turn on the switch unit so as to allow a current to flow between the battery and the first charge storage component and to turn off the switch unit so as to stop the current. The energy transfer unit is configured to, after the switch unit is turned on and then turned off, start removing first energy from the first charge storage component and complete transferring the removed first energy to an energy storage component. The circuit for heating the battery is configured to heat the battery by at least discharging the battery.

摘要翻译： 电池加热电路及方法。 电路包括具有第一阻尼部件和第一电流存储部件的电池，开关部，切换控制部，第一电荷存储部和能量传送部。 开关控制部件被配置为打开开关单元，以允许电流在电池和第一电荷存储部件之间流动并且关闭开关单元以停止电流。 能量传递单元被配置为在开关单元接通然后关闭之后，开始从第一电荷存储部件去除第一能量，并将所移除的第一能量完全转移到能量存储部件。 用于加热电池的电路被配置为通过至少排出电池来加热电池。

公开(公告)号：US08937458B2

公开(公告)日：2015-01-20

申请号：US13187279

申请日：2011-07-20

申请人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Xianyin Li

发明人： Wenhui Xu ,  Yaochuan Han ,  Wei Feng ,  Qinyao Yang ,  Wenjin Xia ,  Xianyin Li

IPC分类号： H01M10/46 ,  H02J7/00 ,  H01L23/34 ,  H01M10/615 ,  H01M10/625 ,  H01M10/657 ,  H01M10/6571 ,  H02M3/158

摘要： A circuit for heating a battery includes a switch unit, control module, damping component, energy storage circuit, and superposition unit. The energy storage circuit forms a loop with the battery, and includes current and charge storage components. The damping component, switch unit, current storage component, and charge storage component connect in series. The control module switches on the switch unit so current flows between the battery and energy storage circuit and switches off the switch unit to stop current flow. The superposition unit superposes energy in the energy storage circuit with energy in the battery after the switch unit switches on and off. The control module switches the switch unit off after the first positive half cycle of current flow through the switch unit after the switch unit switches on. Voltage applied to the switch unit when the switch unit switches off is lower than the switch unit's voltage rating.