Process for preparing ketones
    72.
    发明授权
    Process for preparing ketones 失效
    制备酮的方法

    公开(公告)号:US4014889A

    公开(公告)日:1977-03-29

    申请号:US586118

    申请日:1975-06-11

    Abstract: Ketones are prepared by reacting an aromatic or heterocyclic aldehyde in the presence of a cyanide ion with an unsaturated compound having the formula (I): ##STR1## wherein R.sup.1, R.sup.2 and R.sup.3 are the same or different and are selected from the group of hydrogen, optionally substituted aliphatic, cycloaliphatic, araliphatic, aromatic, heterocyclic and carboxylic acid ester andR.sup.4 is nitrile (CN), --CO--R.sup.5 or --CO--OR.sup.5whereinR.sup.5 is selected from the group of optionally substituted aliphatic, cycloaliphatic, araliphatic, aromatic and heterocyclic andR.sup.1 and R.sup.2 and/or R.sup.1 and R.sup.3 and/or R.sup.2 and R.sup.5 or R.sup.3 and R.sup.5 together with the carbon atoms to which they are attached as substituents may also form a carbocyclic or heterocyclic ring.Ketones prepared according to the process of the invention have the formula: ##STR2## wherein R.sup.1 .sup.' and R.sup.3 .sup.' are identical or different and are selected from the group of hydrogen, lower alkyl having up to 3 C-atoms and optionally substituted phenyl; andR.sup.6 .sup.' is optionally substituted phenyl or a pyridyl.

    Abstract translation: 酮在氰化物离子存在下与具有式(I)的不饱和化合物反应制备:其中R1,R2和R3相同或不同,并且选自 氢,任选取代的脂族,脂环族,芳脂族,芳族,杂环和羧酸酯,R4是腈(CN),-CO-R5或-CO-OR5,其中R5选自任选取代的脂族,脂环族, 芳烷基,芳族和杂环,R 1和R 2和/或R 1和R 3和/或R 2和R 5或R 3和R 5与它们所连接的碳原子作为取代基也可以形成碳环或杂环。

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