公开(公告)号：US4997420A

公开(公告)日：1991-03-05

申请号：US458506

申请日：1989-12-28

申请人： Robert J. LeFevre

发明人： Robert J. LeFevre

IPC分类号： A61M5/145 ,  F16J10/02

CPC分类号： F16J10/02 ,  A61M5/145 ,  Y10S128/12

摘要： A portable drug delivery device for delivering a drug in liquid or fluid form at a constant and self-regulated rate to a patient comprises a syringe having spring loaded piston reciprocal in a cylinder having a reverse taper to pressurize the drug to be dispensed. The reverse taper on the cylinder results in decreasing friction on the piston as the piston moves in the cylinder during a dispensing cycle, and is designed to compensate for the decreasing force exerted on the piston by the expanding spring. A length of tubing connected to the syringe conveys the drug to a needle or other device for administering the drug to a patient, and a restrictor in the length of tubing impedes flow of the drug to achieve a desired flow rate. The restrictor may be sized to achieve any desired flow rate, and in a preferred form of the invention comprises a laser-burned hole in a fitting attached to the outlet end of the length of tubing.

公开(公告)号：US4968301A

公开(公告)日：1990-11-06

申请号：US305972

申请日：1989-02-02

申请人： Giorgio di Palma ,  Victor L. Bartholomew

发明人： Giorgio di Palma ,  Victor L. Bartholomew

IPC分类号： A61M5/142 ,  A61M5/152

CPC分类号： A61M5/152 ,  A61M5/14244 ,  Y10S128/12

摘要： A disposable IV infusion device for ambulatory patients comprises a disk-shaped cover plate and a disk-shaped impeller plate which are interconnected by a stretched membrane that joins the edge of the cover plate with the edge of the impeller plate. The effect of the membrane is to urge the plates into juxtaposition. A fluid port is formed on the cover plate for fluid communication through the port with a collapsible fluid chamber established between the plates. Fluid, when injected into the chamber between the plates, is subsequently expelled through the port for controlled infusion to a patient as the membrane pulls the plates toward each other to collapse the chamber.

公开(公告)号：US4952124A

公开(公告)日：1990-08-28

申请号：US843067

申请日：1986-03-24

申请人： Mitsuji Ogami

发明人： Mitsuji Ogami

IPC分类号： A61M5/142 ,  F04B43/08

CPC分类号： F04B43/082 ,  Y10S128/12

摘要： A medicine injector includes a finger pump which comprises an injection tube containing a liquid medicine and a plurality of fingers adapted to move in a specified sequence to compress this tube. The widths of these fingers are effectively varied by simultaneously compressing the tube with specified two or more of these fingers. This has the effect of increasing the amount of liquid which can be ejected out of the tube and to minimize the effects of a backflow.

摘要翻译： 药剂注射器包括指泵，其包括含有液体药物的注射管和适于以指定顺序移动以压缩该管的多个指状物。 通过用这些手指中的两个或更多个同时压缩管，可以有效地改变这些手指的宽度。 这具有增加可以从管中喷出的液体的量并且使回流的影响最小化的效果。

公开(公告)号：US4878896A

公开(公告)日：1989-11-07

申请号：US128009

申请日：1987-12-01

申请人： Michi E. Garrison ,  John P. Pelmulder

发明人： Michi E. Garrison ,  John P. Pelmulder

IPC分类号： A61M5/00 ,  A61M1/00 ,  A61M5/142 ,  G06K7/10

CPC分类号： G06K7/10861 ,  A61M5/142 ,  A61M5/365 ,  A61M2205/12 ,  A61M2205/6018 ,  A61M2205/6063 ,  Y10S128/12

摘要： A cassette identification system for use with a medication infusion system having disposable cassettes which are mounted onto a main pump unit is disclosed which uses an optical sensor module to read the identifying bits from the cassette. The identification indicia contained on the cassette each either pass light through a portion of the cassette, or diffuse the light to prevent it from passing through the cassette. The optical module is mounted on the main pump unit, and includes light sources and sensors for each of the identification indicia on the cassette; the system may use either redundant or non-redundant coding for identifying the cassettes.

公开(公告)号：US4838860A

公开(公告)日：1989-06-13

申请号：US67700

申请日：1987-06-26

申请人： Leroy E. Groshong ,  Judson C. Groshong ,  R. James Brawn, deceased

发明人： Leroy E. Groshong ,  Judson C. Groshong ,  R. James Brawn, deceased

IPC分类号： A61M5/142

CPC分类号： A61M5/1422 ,  A61M2205/12 ,  Y10S128/12

摘要： An infusion pump for administering fluid from a fluid source to a patient comprises a base member having an electric motor for driving a fluid pump housed within a cassette detachably mountable on the base and connectable to the motor. The cassette houses a reciprocative piston and cylinder assembly which both pumps fluid to the patient while simultaneously drawing fluid from the fluid source so as to maintain a continuous flow rate of fluid to the patient. The cassette also houses deformably closable pairs of tubes connecting each of the pump's two fluid chambers to the cassette inlet and outlet respectively to provide the necessary valving to produce continuous flow in cooperation with the reciprocative piston and cylinder assembly. The fluid flow rate is adjustably controlled by a microcomputer which regulates the motor by repeatedly initiating electric motor driving pulses at a predetermined time rate, and terminating them in response to the advancement of the motor beyond one of a plurality of predetermined positions so as to maximize accuracy and reliability of flow rate while compatibly maximizing the power efficiency of the motor for portable applications requiring a battery power source.

摘要翻译： 一种用于将流体从流体源施用到患者的输液泵包括具有用于驱动容纳在可拆卸地安装在基座上并可连接到马达的盒内的流体泵的电动马达的基座构件。 所述盒装有往复式活塞和气缸组件，它们将流体泵送到患者身上同时从流体源抽出流体，以保持流体到患者的连续流速。 盒式磁带还容纳可变形地闭合的一对管，其将泵的两个流体室中的每一个分别连接到盒的入口和出口，以提供必要的阀，以与往复式活塞和气缸组件配合产生连续的流动。 流体流量由微型计算机调节，该微型计算机通过以预定的时间速率反复启动电动机驱动脉冲来调节电动机，并且响应于电动机超前于多个预定位置之一而终止它们， 流量的准确性和可靠性，同时最大限度地提高了需要电池电源的便携式应用的电机的功率效率。

公开(公告)号：US4808167A

公开(公告)日：1989-02-28

申请号：US4352

申请日：1987-01-16

申请人： Alfred E. Mann ,  Joseph H. Schulman

发明人： Alfred E. Mann ,  Joseph H. Schulman

IPC分类号： A61M5/00 ,  A61B19/00 ,  A61M5/14 ,  A61M5/142 ,  A61M5/50 ,  A61M1/00

CPC分类号： A61M5/1413 ,  A61B2090/0814 ,  A61M5/14244 ,  A61M5/50 ,  Y10S128/12

摘要： A disposable cassette for use with a main infusion pump unit is disclosed which contains both a disposable pump and a battery, thereby requiring the simultaneous replacement of both the pump and the battery. The controller contained in the main pump unit includes a timer which prevents the cassette from being used for longer than a predetermined time, which is substantially less than the life of the battery. An interlock prevents a cassette from being reinstalled following a single use.

公开(公告)号：US4808161A

公开(公告)日：1989-02-28

申请号：US22167

申请日：1987-03-05

申请人： Dean L. Kamen

发明人： Dean L. Kamen

IPC分类号： A61M5/00 ,  A61M5/14 ,  A61M5/168 ,  A61M5/36 ,  A61M39/26 ,  F04B43/02 ,  F04B43/04 ,  F04B43/067 ,  F04B49/06 ,  F16K31/00 ,  G01P13/00

CPC分类号： F16K31/005 ,  A61M5/16809 ,  A61M5/16813 ,  A61M5/16859 ,  A61M5/365 ,  F04B43/043 ,  G01F11/086 ,  G01P13/0066 ,  A61M2005/1403 ,  A61M2205/15 ,  A61M39/26 ,  Y10S128/12 ,  Y10S128/13 ,  Y10T137/7782 ,  Y10T137/7796 ,  Y10T137/88005

摘要： A system is provided for controlling flow of a first fluid through a line. Dispensing means isolates a region of the first fluid in the line from effects of pressure in the line outside of the region and repetitively dispenses into and out of the region volume increments of first fluid. Measurement fluid housing means houses measurement fluid in communication with the region such that the dispensing of increments of first fluid into or out of the region causes a change in the measurement fluid pressure. Displacement means displaces a predetermined volume increment of measurement fluid into and out of the measurement fluid housing means, such that displacement of the predetermined volume increment causes a change in the measurement fluid pressure when the region is isolated by the dispensing means. Pressure measurement means measures changes in measurement fluid pressure. Control means, in communication with the pressure measurement means, the displacement means, and the dispensing means, causes the dispensing means to dispense first fluid in increments based on data from the pressure measurement means, such that at least one of the predetermined volume increments of measurement fluid displaced serves as a reference for the volume increments of first fluid outputted.

摘要翻译： 提供了一种用于控制通过管线的第一流体的流动的系统。 分配装置将管线中的第一流体的区域与区域内的管线中的压力的​​影响隔离，并重复地分配和排出第一流体的区域容积增量。 测量流体容纳装置容纳与该区域连通的测量流体，使得第一流体的增量分配进入或流出该区域导致测量流体压力的变化。 排量意味着将测量流体的预定体积增量移入和移出测量流体容纳装置，使得当区域被分配装置隔离时，预定体积增量的移位导致测量流体压力的变化。 压力测量意味着测量流体压力的变化。 控制装置与压力测量装置连通，位移装置和分配装置使得分配装置基于来自压力测量装置的数据以增量分配第一流体，使得至少一个预定体积增量 排出的测量流体用作输出的第一流体的体积增量的参考。

公开(公告)号：US4798589A

公开(公告)日：1989-01-17

申请号：US62488

申请日：1987-06-15

申请人： Gus G. Tseo

发明人： Gus G. Tseo

IPC分类号： A61M5/142 ,  A61M5/20

CPC分类号： A61M5/14216 ,  Y10S128/12

摘要： The present invention is directed to an improved cassette for use in an intravenous infusion pump. The cassette of the present invention includes a cassette body which is capable of being removably secured within a volumetric pump. The cassette body has a volumetric chamber of predetermined volume which is placed in communication with an inlet and an outlet. The volumetric cassette includes an inlet corridor through which fluid may flow into the cassette. The inlet corridor in turn flows into a central corridor which leads directly to the volumetric chamber. The cassette also includes an outlet corridor which is also in communication with the central corridor and, in turn, the volumetric chamber. Fluid will, therefore, exit the volumetric chamber through the outlet corridor by way of the central corridor. The outlet corridor is then connected to the patient infusion line. The cassette of the present invention also includes a plunger which reciprocates within the interior of the volumetric chamber.The present invention teaches the use of a diaphragm which covers the portion of the plunger which is exposed to the volumetric chamber. The diaphragm forms a friction seal with the exterior of the cassette body. The diaphragm is formed such that it reciprocates along with the plunger even though it is not securely attached to the plunger. As a result, when the plunger withdraws from the volumetric chamber, the diaphragm withdraws a corresponding distance. When the plunger again enters the volumetric chamber, the diaphragm enters as well.

摘要翻译： 本发明涉及用于静脉输液泵的改进盒。 本发明的盒子包括能够可拆卸地固定在体积泵内的盒体。 盒体具有与入口和出口连通的预定体积的容积室。 体积盒包括入口走廊，流体可以通过入口走廊流入盒中。 入口走廊又流入一个直接通向容积室的中央走廊。 该盒还包括出口走廊，该出口走廊也与中央走廊连通，而又与容积腔连通。 因此，流体将通过出口走廊通过中央走廊离开容积室。 出口走廊然后连接到患者输液管线。 本发明的盒还包括在体积腔内部往复运动的柱塞。 本发明教导了使用覆盖柱塞的暴露于容积腔的部分的隔膜。 隔膜与盒体的外部形成摩擦密封。 膜片形成为使得其与柱塞一起往复运动，即使其没有牢固地附接到柱塞。 结果，当柱塞从容积室中退出时，隔膜取出相应的距离。 当柱塞再次进入容积室时，隔膜也进入。

公开(公告)号：US4758228A

公开(公告)日：1988-07-19

申请号：US931506

申请日：1986-11-17

申请人： David R. Williams

发明人： David R. Williams

IPC分类号： A61M5/142 ,  A61M1/00

CPC分类号： A61M5/14232 ,  A61M5/142 ,  A61M5/16854 ,  A61M5/365 ,  A61M2205/3317 ,  A61M2205/3375 ,  Y10S128/12

摘要： A medical infusion pump includes a housing (10), a pump assembly (30), a bubble sensor assembly (120), a pressure sensor assembly (140) and a flow control assembly (180). The pump assembly includes a ring (26) with teeth (44) and a wheel (46) mounted for eccentric rotation within the ring. The pumping action is developed by the rotation of the wheel which continuously closes a portion of tubing (36) against one or two teeth as it goes through the pumping cycle. The bubble sensor includes a pair of sensor blocks (124) defining a generally V-shaped trough for cradling a portion of the tubing. The pressure sensor assembly detects pressure variations by movement of a diaphragm (168) coupled to a magnet (162) which is operatively coupled to a Hall effect circuit (160). The flow control assembly includes a thumb wheel (196) having a cam groove (197) interacting with a valve stem (199) for controlling the fluid flow through an orifice and associated valve seat (194).

摘要翻译： 医用输液泵包括壳体（10），泵组件（30），气泡传感器组件（120），压力传感器组件（140）和流量控制组件（180）。 泵组件包括具有齿（44）的环（26）和安装成在环内偏心旋转的轮（46）。 泵的作用是通过轮的旋转而产生的，当轮经过泵送循环时，轮的旋转将连续地关闭管（36）的一部分或两个齿。 气泡传感器包括一对传感器块（124），该传感器块（124）限定一个大体上为V形的槽，用于支架管道的一部分。 压力传感器组件通过耦合到可操作地耦合到霍尔效应电路（160）的磁体（162）的隔膜（168）的移动来检测压力变化。 流量控制组件包括具有与阀杆（199）相互作用的凸轮槽（197）的指轮（196），用于控制通过孔口和相关联的阀座（194）的流体流动。

公开(公告)号：US4713054A

公开(公告)日：1987-12-15

申请号：US836010

申请日：1986-03-04

申请人： L. Thomas Kelly ,  Esther V. M. Hamel ,  Robert P. Bielka

发明人： L. Thomas Kelly ,  Esther V. M. Hamel ,  Robert P. Bielka

IPC分类号： A61D7/00 ,  A61D13/00 ,  G01K13/00 ,  A61M5/00

CPC分类号： A61D7/00 ,  A61D13/00 ,  G01K13/002 ,  Y10S128/12

摘要： A muscle powered liquid dispensing insert is provided for use with an implanted anchor having a hollow anchor sleeve extending into the subcutaneous fascia of a region behind an animal's ear. The insert includes one or more balloon-like reservoirs, each containing a drug or other medicant in substantially liquid form. Each reservoir means additionally provides effective means for anchoring the insert in the animal. A pump assembly draws the medicant(s) from the reservoir(s), and dispenses such to the animal. The pump assembly has a toroidal pump body defining a pump chamber and including a flexible impermeable pump diaphragm. The pump chamber communicates through inlet check valve means with each of the reservoirs, and through outlet check valve means with the tissue of the animal. The outlet check valve means operate at a higher activation pressure than the inlet check valve means. A piston powered solely by the animal's muscle and tissue operates the pump diaphragm. One or more tubes communicating through the interior of the anchor sleeve between an associated reservoir and a self-sealing opening allow the reservoirs to be refilled. A cap and plug seal the anchor sleeve against the entry of contaminants and other foreign material, and support the self-sealing ends of the tubes. The plug can be removed to allow the insert to be removed from the anchor by means of a suitable tool.

摘要翻译： 提供肌肉动力的液体分配插入件用于具有延伸到动物耳朵后面的区域的皮下筋膜的中空锚定套筒的植入锚固件。 插入物包括一个或多个气囊样储存器，每个储存器包含基本上液体形式的药物或其它药剂。 每个储存器装置另外提供用于将插入物锚定在动物中的有效装置。 泵组件从储存器抽取药剂，并将其分配给动物。 泵组件具有限定泵室的环形泵体，并且包括柔性不可渗透的泵隔膜。 泵室通过入口止回阀装置与每个储存器连通，并且通过出口止回阀装置与动物的组织连通。 出口止回阀装置在比进口止回阀装置更高的启动压力下工作。 仅由动物的肌肉和组织供电的活塞操作泵隔膜。 一个或多个管通过锚定套筒的内部在相关联的储存器和自密封开口之间连通，允许储存器被再填充。 盖子和塞子密封锚定套筒以防止污染物和其他异物进入，并支撑管子的自密封端。 可以移除塞子以允许插入件通过合适的工具从锚固件移除。