公开(公告)号：US20070252980A1

公开(公告)日：2007-11-01

申请号：US11413377

申请日：2006-04-28

申请人： Shih-Yuan Wang ,  Zhiyong Li

发明人： Shih-Yuan Wang ,  Zhiyong Li

IPC分类号： G01J3/44 ,  G01N21/65

CPC分类号： G01J3/02 ,  G01J3/0208 ,  G01N21/658

摘要： Raman-enhancing structures include a layer of dielectric material, a superlens configured to focus electromagnetic radiation having a wavelength greater than about 100 nanometers to a two-dimensional focal area having linear dimensions less than about 100 nanometers on a surface of the layer of dielectric material, and at least two nanoparticles comprising a Raman-enhancing material disposed proximate the focal area. Additional Raman-enhancing structures include a layer of dielectric material, a layer of conductive material, and at least two nanoparticles comprising a Raman-enhancing material disposed on a second, opposite surface of the layer of dielectric material. The layer of conductive material has a plurality of apertures therethrough that are arranged in a two-dimensional array. Methods for conducting Raman spectroscopy are performed using such structures and systems.

摘要翻译： 拉曼增强结构包括介电材料层，配置成将具有大于约100纳米的波长的电磁辐射聚焦到具有小于约100纳米的线性尺寸的二维聚焦区域的超薄膜在电介质材料层的表面上 以及至少两个纳米颗粒，其包含靠近焦点区域设置的拉曼增强材料。 附加的拉曼增强结构包括电介质材料层，导电材料层，以及至少两个包含拉曼增强材料的纳米颗粒，该拉曼增强材料设置在电介质材料层的第二相对表面上。 导电材料层具有以二维阵列布置的穿过其中的多个孔。 使用这种结构和系统进行拉曼光谱的方法。

公开(公告)号：US07158219B2

公开(公告)日：2007-01-02

申请号：US10942693

申请日：2004-09-16

申请人： Zhiyong Li ,  Shih-Yuan Wang

发明人： Zhiyong Li ,  Shih-Yuan Wang

IPC分类号： G01N1/00 ,  G01J3/44

CPC分类号： G01N21/658 ,  B82Y30/00

摘要： A SERS-active structure is disclosed that includes a substrate and at least one nanowire disposed on the substrate. The at least one nanowire includes a core including a first material and a coating including a SERS-active material. A SERS system is also disclosed that includes a SERS-active structure. Also disclosed are methods for forming a SERS-active structure and methods for performing SERS with SERS-active structures.

摘要翻译： 公开了一种SERS-活性结构，其包括衬底和设置在衬底上的至少一个纳米线。 所述至少一个纳米线包括包含第一材料和包含SERS-活性材料的涂层的芯。 还公开了包括SERS活性结构的SERS系统。 还公开了形成SERS活性结构的方法和用SERS活性结构进行SERS的方法。

公开(公告)号：US20060077382A1

公开(公告)日：2006-04-13

申请号：US10964523

申请日：2004-10-13

申请人： Shih-Yuan Wang ,  Zhiyong Li ,  M. Islam

发明人： Shih-Yuan Wang ,  Zhiyong Li ,  M. Islam

IPC分类号： G01J3/44 ,  G01N21/65

CPC分类号： G01N21/658

摘要： Devices, systems, and methods using Surface Enhanced Raman Spectroscopy (SERS) are disclosed. A device for generating Raman scattered radiation comprises a laser source and a SERS-active structure. The laser source may be configured for emanating radiation from an emanating surface or by forming a depression in the laser source, which creates a region of increased evanescent field from the laser source. SERS systems and methods include a device for generating Raman scattered radiation with a detector configured to receive the Raman scattered radiation.

摘要翻译： 公开了使用表面增强拉曼光谱（SERS）的器件，系统和方法。 用于产生拉曼散射辐射的装置包括激光源和SERS-活性结构。 激光源可以被配置用于从发射表面发射辐射，或者通过在激光源中形成凹陷，其产生从激光源增加的渐逝场的区域。 SERS系统和方法包括用配置成接收拉曼散射辐射的检测器产生拉曼散射辐射的装置。

公开(公告)号：US20060055922A1

公开(公告)日：2006-03-16

申请号：US10942482

申请日：2004-09-16

申请人： Zhiyong Li ,  Shih-Yuan Wang

发明人： Zhiyong Li ,  Shih-Yuan Wang

IPC分类号： G01J3/44 ,  G01N21/65

CPC分类号： G01N21/658

摘要： SERS-active structures including features having nanoscale dimensions are disclosed, including methods for forming such SERS-active structures and methods for forming a plurality of such SERS-active structures. Methods for performing SERS using SERS-active structures also are disclosed.

摘要翻译： 公开了包括具有纳米级尺寸的特征的SERS活性结构，包括形成这种SERS-活性结构的方法和形成多个这样的SERS-活性结构的方法。 还公开了使用SERS活性结构来执行SERS的方法。

公开(公告)号：US20150241355A1

公开(公告)日：2015-08-27

申请号：US14406653

申请日：2012-07-31

申请人： Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Steven Barcelo ,  Ansoon Kim ,  Mineo Yamakawa ,  Zhang-Lin Zhou ,  Huei Pei Kuo

发明人： Shih-Yuan Wang ,  Gary Gibson ,  Zhiyong Li ,  Alexandre M. Bratkovski ,  Steven Barcelo ,  Ansoon Kim ,  Mineo Yamakawa ,  Zhang-Lin Zhou ,  Huei Pei Kuo

IPC分类号： G01N21/65 ,  A61F2/02 ,  A61F2/82 ,  G02B5/10

CPC分类号： G01N21/658 ,  A61F2/02 ,  A61F2/82 ,  G01N2201/068 ,  G02B5/10 ,  Y10T29/49826

摘要： According to an example, an apparatus for performing spectroscopy includes a parabolic reflector and a plurality of surface-enhanced Raman spectroscopy (SERS) elements spaced from the parabolic reflector and positioned substantially at a focal point of the parabolic reflector. The parabolic reflector is to reflect Raman scattered light emitted from molecules in a near field generated by the plurality of SERS elements to substantially increase the flux of the Raman scattered light emitted out of the apparatus.

摘要翻译： 根据一个实例，用于执行光谱学的装置包括抛物面反射器和与抛物面反射器间隔开并且基本上位于抛物面反射器的焦点的多个表面增强拉曼光谱（SERS）元件。 抛物面反射器是反射由多个SERS元件产生的近场中的分子发射的拉曼散射光，以大大增加从该装置发出的拉曼散射光的通量。

公开(公告)号：US08542355B2

公开(公告)日：2013-09-24

申请号：US13383078

申请日：2009-07-08

申请人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

发明人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

IPC分类号： G01J3/44

CPC分类号： G01N21/658 ,  B82Y20/00

摘要： A light amplifying device for surface enhanced Raman spectroscopy is disclosed herein. The device includes a dielectric layer having two opposed surfaces. A refractive index of the dielectric layer is higher than a refractive index of a material or environment directly adjacent thereto. At least one opening is formed in one of the two opposed surfaces of the dielectric layer, and at least one nano-antenna is established on the one of the two opposed surfaces of the dielectric layer. A gain region is positioned in the dielectric layer or adjacent to another of the two opposed surfaces of the dielectric layer.

摘要翻译： 本文公开了一种用于表面增强拉曼光谱的光放大装置。 该装置包括具有两个相对表面的电介质层。 电介质层的折射率高于与其直接相邻的材料或环境的折射率。 至少一个开口形成在电介质层的两个相对表面之一中，并且至少一个纳米天线被建立在电介质层的两个相对表面之一上。 增益区域位于电介质层中或邻近电介质层的两个相对表面中的另一个。

公开(公告)号：US20120013903A1

公开(公告)日：2012-01-19

申请号：US13258391

申请日：2009-07-30

申请人： Huei Pei Kuo ,  Shih-Yuan Wang ,  David A. Fattal ,  Jingjing Li ,  Nobuhiko Kobayashi ,  Zhiyong Li

发明人： Huei Pei Kuo ,  Shih-Yuan Wang ,  David A. Fattal ,  Jingjing Li ,  Nobuhiko Kobayashi ,  Zhiyong Li

IPC分类号： G01J3/44 ,  B82Y20/00 ,  B82B1/00

CPC分类号： G01N21/658

摘要： Embodiments of the present invention are directed to systems for performing surface-enhanced Raman spectroscopy. In one embodiment, a system (100, 400, 600, 800, 900, 950) for performing Raman spectroscopy comprises a substrate (102) substantially transparent to a range of wavelengths of electromagnetic radiation and a plurality of nanowires (104, 602) disposed on a surface of the substrate. The nanowires are substantially transparent to the range of wavelengths of electromagnetic radiation. The system includes a material disposed on each of the nanowires. The electromagnetic radiation is transmitted within the substrate, into the nanowires, and emitted from the ends of the nanowires to produce enhanced Raman scattered light from molecules located on or in proximity to the material.

摘要翻译： 本发明的实施例涉及用于进行表面增强拉曼光谱的系统。 在一个实施例中，用于执行拉曼光谱的系统（100,400,600,800,900,950）包括对电磁辐射的波长范围基本上透明的基底（102）和设置的多个纳米线（104,602） 在基板的表面上。 纳米线对于电磁辐射的波长范围基本上是透明的。 该系统包括设置在每个纳米线上的材料。 电磁辐射在衬底内传输到纳米线中，并从纳米线的端部发射，以产生来自位于材料上或附近的分子的增强的拉曼散射光。

公开(公告)号：US07474397B2

公开(公告)日：2009-01-06

申请号：US11413377

申请日：2006-04-28

申请人： Shih-Yuan Wang ,  Zhiyong Li

发明人： Shih-Yuan Wang ,  Zhiyong Li

IPC分类号： G01J3/44

CPC分类号： G01J3/02 ,  G01J3/0208 ,  G01N21/658

摘要： Raman-enhancing structures include a layer of dielectric material, a superlens configured to focus electromagnetic radiation having a wavelength greater than about 100 nanometers to a two-dimensional focal area having linear dimensions less than about 100 nanometers on a surface of the layer of dielectric material, and at least two nanoparticles comprising a Raman-enhancing material disposed proximate the focal area. Additional Raman-enhancing structures include a layer of dielectric material, a layer of conductive material, and at least two nanoparticles comprising a Raman-enhancing material disposed on a second, opposite surface of the layer of dielectric material. The layer of conductive material has a plurality of apertures therethrough that are arranged in a two-dimensional array. Methods for conducting Raman spectroscopy are performed using such structures and systems.

摘要翻译： 拉曼增强结构包括介电材料层，配置成将具有大于约100纳米的波长的电磁辐射聚焦到具有小于约100纳米的线性尺寸的二维聚焦区域的超薄膜在电介质材料层的表面上 以及至少两个纳米颗粒，其包含靠近焦点区域设置的拉曼增强材料。 附加的拉曼增强结构包括电介质材料层，导电材料层，以及至少两个包含拉曼增强材料的纳米颗粒，该拉曼增强材料设置在电介质材料层的第二相对表面上。 导电材料层具有以二维阵列布置的穿过其中的多个孔。 使用这种结构和系统进行拉曼光谱的方法。

公开(公告)号：US07307719B2

公开(公告)日：2007-12-11

申请号：US10941714

申请日：2004-09-14

申请人： Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

发明人： Shih-Yuan Wang ,  M. Saif Islam ,  Zhiyong Li

IPC分类号： G01J3/44 ,  G01J3/45

CPC分类号： G01N21/658 ,  G01J3/26

摘要： Wavelength-tunable radiation amplifying structures for Raman spectroscopy are disclosed that include resonant cavities having Raman signal-enhancing structures disposed therein. Systems that include the amplifying structures and methods of performing spectroscopic analysis using the structures and systems are also disclosed.

摘要翻译： 公开了用于拉曼光谱的波长可调辐射放大结构，其包括其中布置有拉曼信号增强结构的谐振腔。 还公开了包括放大结构的系统和使用该结构和系统进行光谱分析的方法。

公开(公告)号：US20070122313A1

公开(公告)日：2007-05-31

申请号：US11291019

申请日：2005-11-30

申请人： Zhiyong Li ,  M. Islam ,  Shih-Yuan Wang

发明人： Zhiyong Li ,  M. Islam ,  Shih-Yuan Wang

IPC分类号： B01L3/00

CPC分类号： B81C1/00071 ,  B01L3/5027 ,  B01L2300/0896

摘要： A nanochannel apparatus and method of fabrication provide an array of nanochannels with distal open or exposed ends formed in situ through a permanent support. A nanofluidic system includes the nanochannel apparatus, a fluidic interface, and a component interfaced to the nanochannel apparatus. The method includes encasing an array of nanowires in a support, and forming the array of nanochannels in situ in locations of the nanowires, such that distal ends of the nanochannels are exposed.

摘要翻译： 纳米通道装置和制造方法提供具有通过永久支撑原位形成的远端开放或暴露端的纳米通道阵列。 纳米流体系统包括纳米通道装置，流体界面和与纳米通道装置相连接的部件。 该方法包括将纳米线阵列包围在支撑体中，并且在纳米线的位置上原位形成纳米通道阵列，使得纳米通道的远端被暴露。