利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

499 条记录 (耗时 0.028 秒)

    Method for Identifying Fast- Growing Fish
    82.
    发明申请
    Method for Identifying Fast- Growing Fish 失效
    识别快速生长鱼的方法

    公开(公告)号：US20030047143A1

    公开(公告)日：2003-03-13

    申请号：US10190163

    申请日：2002-07-03

    发明人： Jeffrey Todd Streelman ,  Thomas David Kocher

    IPC分类号： A01K061/00

    CPC分类号： A01K67/02 ,  A01K61/10 ,  C12Q1/6888 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/158 ,  Y02A40/81

    摘要： Methods of selecting fish for breeding and optimum growth in conditions of various salinity are disclosed. Fish are selected for growth in specific salinity based on their prolactin 1 genotype. A simple sequence repeat polymorphism (microsatellite) in the tilapia prolactin (prl 1) promoter is associated with differences in prl 1 expression and differences in growth in nullsalt-challengednull or nullsalt-effectednull fishes. This discovery suggests that dinucleotide microsatellites may represent an under-appreciated source of genetic variation for regulatory evolution, and belie the textbook interpretation that non-coding microsatellite length variation lacks functional consequences. Thus, the methods of the invention include determining or selecting the salinity of the environment in which the fish will be grown; determining the prolactin genotype of at least one male and at least one female fish being considered for breeding; breeding male and female fish having the desired genotype(s) to result in offspring having known, predictable genotypes; and raising the fish in a salinity environment compatible with the fishes' genotype(s).

    摘要翻译： 公开了在各种盐度条件下选择鱼类进行育种和最佳生长的方法。 基于它们的催乳素1基因型，选择鱼以特定盐度生长。 罗非鱼催乳素（prl 1）启动子中的简单序列重复多态性（微卫星）与pr1表达的差异和“盐胁迫”或“盐胁迫”鱼的生长差异相关。 这一发现表明，二核苷酸微卫星可能代表了对于调节进化的遗传变异不足的来源，并认为教科书解释非编码微卫星长度变异缺乏功能性后果。 因此，本发明的方法包括确定或选择鱼种植的环境的盐度; 确定正在考虑用于育种的至少一种雄性和至少一种雌性鱼的催乳素基因型; 培育具有所需基因型的雄性和雌性鱼以产生具有已知的可预测基因型的后代; 并在与鱼的基因型相适应的盐度环境中饲养鱼。

    Novel PRKAG3 alleles and use of the same as genetic markers for reproductive and meat quality traits
    83.
    发明申请
    Novel PRKAG3 alleles and use of the same as genetic markers for reproductive and meat quality traits 有权
    新型PRKAG3等位基因和遗传标记与繁殖和肉质性状的相同

    公开(公告)号：US20030017470A1

    公开(公告)日：2003-01-23

    申请号：US09950022

    申请日：2001-09-10

    发明人： Max F. Rothschild ,  Daniel C. Ciobanu ,  Massoud Malek ,  Graham Plastow

    IPC分类号： C12Q001/68 ,  C07H021/04

    CPC分类号： C12Q1/6883 ,  C12Q1/6876 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/172

    摘要： Disclosed herein are genetic markers for animal meat quality and reproductive efficiency, methods for identifying such markers, and methods of screening animals to determine those more likely to produce larger litters and/or better meat quality and preferably selecting those animals for future breeding purposes. The markers are based upon the presence or absence of certain polymorphisms in the PRKAG3 gene.

    摘要翻译： 本文公开了用于动物肉质量和繁殖效率的遗传标记，用于鉴定这些标记的方法，以及筛选动物以确定更可能产生更大的仔猪和/或更好的肉质量并且优选选择那些动物以用于未来育种目的的方法。 标记基于PRKAG3基因中某些多态性的存在或不存在。

    Pig myogenin gene and method to identify polymorphisms related to muscle growth
    84.
    发明授权
    Pig myogenin gene and method to identify polymorphisms related to muscle growth 失效
    猪肌细胞生成素基因和鉴定与肌肉生长相关的多态性的方法

    公开(公告)号：US6143880A

    公开(公告)日：2000-11-07

    申请号：US91899

    申请日：1998-10-02

    申请人： Ann Elisabeth Soumillion ,  Marinus Frederik te Pas

    发明人： Ann Elisabeth Soumillion ,  Marinus Frederik te Pas

    IPC分类号： C07K14/47 ,  C07K14/475 ,  C12Q1/68 ,  C07H21/04 ,  C07H21/02 ,  C12P19/34

    CPC分类号： C07K14/475 ,  C12Q1/6876 ,  C12Q2600/124 ,  C12Q2600/156

    摘要： A novel sequence of the pig myogenin gene and methods of using the myogenin gene and its products. Also disclosed are methods for detecting different alleles of the pig myogenin gene, which different alleles are associated with differences in the genotypic and/or phenotypic traits of the pigs having those alleles. Methods for distinguishing between alleles resulting in different phenotypes, particularly using techniques involving selective amplification of pig myogenin gene derived materials are also disclosed. These techniques are especially suitable for selecting animals to be used in breeding programs. Breeding programs employing such techniques are also disclosed.

    摘要翻译： PCT No.PCT / NL96 / 00497 Sec。 371日期：1998年10月2日 102（e）日期1998年10月2日PCT 1996年12月20日PCT公布。 公开号WO97 / 23644 日期1997年7月3日猪肌细胞生成素基因的新序列和使用肌细胞生成素基因及其产物的方法。 还公开了用于检测猪肌细胞生成素基因的不同等位基因的方法，其不同的等位基因与具有那些等位基因的猪的基因型和/或表型性状的差异相关。 区分导致不同表型的等位基因的方法，特别是使用涉及选择性扩增猪肌发生蛋白基因衍生物质的技术。 这些技术特别适用于选育用于育种程序的动物。 还公开了采用这种技术的育种程序。

    Method of identification of animals resistant or susceptible to disease such as ruminant brucellosis, tuberculosis, paratuberculosis and salmonellosis
    85.
    发明授权
    Method of identification of animals resistant or susceptible to disease such as ruminant brucellosis, tuberculosis, paratuberculosis and salmonellosis 失效
    鉴定抗性或易患疾病如反刍动物布鲁杆菌病，结核病，副结核病和沙门氏菌病的方法

    公开(公告)号：US6114118A

    公开(公告)日：2000-09-05

    申请号：US903139

    申请日：1997-07-30

    申请人： Joe W. Templeton ,  Jianwei Feng ,  L. Garry Adams ,  Erwin Schurr ,  Philippe Gros ,  Donald S. Davis ,  Roger Smith, III

    发明人： Joe W. Templeton ,  Jianwei Feng ,  L. Garry Adams ,  Erwin Schurr ,  Philippe Gros ,  Donald S. Davis ,  Roger Smith, III

    IPC分类号： C12Q1/68 ,  C12P19/34

    CPC分类号： C12Q1/6883 ,  C12Q2600/124 ,  C12Q2600/156 ,  C12Q2600/158

    摘要： The present invention relates to materials and methods for identifying animals that are resistant or susceptible to diseases associated with intracellular parasites such as brucellosis, tuberculosis, paratuberculosis and salmonellosis. More particularly, the present invention relates to the identification of a gene, called NRAMP1, which is associated with the susceptibility or resistance of an animal, such as an artiodactyla to diseases such as brucellosis, tuberculosis, paratuberculosis and salmonellosis. Still more particularly, the present invention relates to the identification of specific sequences of bovine NRAMP1 which associate with resistance or susceptibility to ruminant brucellosis, tuberculosis, paratuberculosis and salmonellosis, and to the method of identifying said sequences to identify animals who are susceptible or resistant to disease.

    摘要翻译： 本发明涉及用于鉴定对细胞内寄生虫如布鲁氏杆菌病，结核病，副结核病和沙门氏菌病相关疾病具有抗性或易感性的动物的材料和方法。 更具体地，本发明涉及称为NRAMP1的基因的鉴定，其与诸如布鲁氏杆菌病，结核病，副结核分枝杆菌和沙门氏菌病之类的疾病如动物的易感性或抗性相关。 更具体地，本发明涉及鉴定与抗反刍动物布鲁氏菌病，结核病，副结核和沙门氏菌病的抗性或易感性相关的牛NRAMP1的特异性序列，以及鉴定所述序列以识别易感或抗性的动物的方法 疾病。

    Genetic marker for superior milk products in dairy cattle
    90.
    发明授权
    Genetic marker for superior milk products in dairy cattle 失效
    奶牛优质奶制品的遗传标记

    公开(公告)号：US5041371A

    公开(公告)日：1991-08-20

    申请号：US324278

    申请日：1989-03-15

    申请人： Charles M. Cowan ,  Margaret R. Dentine ,  Roy L. Ax ,  Linda A. Schuler

    发明人： Charles M. Cowan ,  Margaret R. Dentine ,  Roy L. Ax ,  Linda A. Schuler

    IPC分类号： A01K67/02 ,  C12Q1/68

    CPC分类号： C12Q1/6876 ,  C12Q1/683 ,  C12Q2600/124 ,  C12Q2600/156

    摘要： An assay for a genetic marker associated with increased milk production is disclosed. Also disclosed are kits for use in connection with the assay and breeding methods that use the assay. The assay centers on finding a genetic marker in a bovine cell (e.g. in the DNA of the cell). The presence of the marker is confirmed by exposing a gene sequence from the cell to a restriction enzyme so as to yield gene fragments of varying lengths. During a separation step there is a separation of some of the fragments from others (such as by using electrophoresis), and there is then a hybridization of a plurality of probes that contain a portion of bovine prolactin sequence to the separated fragments. The probe is radiolabelled. Then, there is a comparison of the results of the hybridization with the hybridization results for a gene sequence known to either have the marker or not have the marker. The assay appears to be of greatest utility in connection with the Carlin-M Ivanhoe Bell Holstein family.

    摘要翻译： 公开了与增加的奶产量相关的遗传标记的测定。 还公开了用于与使用该测定法的测定和育种方法相结合的试剂盒。 测定的重点是在牛细胞中找到遗传标记（例如在细胞的DNA中）。 通过将基因序列从细胞暴露于限制酶来确认标记物的存在，从而产生不同长度的基因片段。 在分离步骤期间，其中一些片段与其他片段分离（例如通过使用电泳），然后将含有一部分牛催乳素序列的多个探针与分离的片段杂交。 探针放射性标记。 然后，将已知具有标记或不具有标记的基因序列的杂交结果与杂交结果进行比较。 该检测似乎与Carlin-M Ivanhoe Bell Holstein家族有关。