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公开(公告)号:US07566700B2
公开(公告)日:2009-07-28
申请号:US10590680
申请日:2005-02-25
CPC分类号: C12N15/113 , C12N2310/14
摘要: siRNA molecules are disclosed which target the transcription factor STAT6 and repress the expression of STAT6 mRNA, STAT6 protein and STAT6 function in lung cells. The use of STAT6 specific siRNA molecules in the treatment of allergic diseases of the respiratory tract such as asthma and rhinitis is disclosed.
摘要翻译: 公开了靶向转录因子STAT6并抑制肺细胞中STAT6 mRNA,STAT6蛋白和STAT6功能的表达的siRNA分子。 公开了使用STAT6特异性siRNA分子治疗呼吸道过敏性疾病如哮喘和鼻炎。