公开(公告)号：US20220323143A1

公开(公告)日：2022-10-13

申请号：US17711574

申请日：2022-04-01

申请人： CardioFocus, Inc.

发明人： Gerald Melsky ,  Brian Estabrook ,  Burke Barrett ,  Jeff Brown ,  Lincoln Baxter ,  Kevin Zephir ,  Curtis Keohane ,  Omar Colon

IPC分类号： A61B18/14 ,  A61B18/12

摘要： A method for ablating target tissue includes the steps of: (a) delivering an ablation balloon catheter to the target tissue, wherein the ablation balloon catheter includes a compliant balloon, a visualization device; and an electrode array that is visible to the visualization device, each electrode being configured to deliver ablation energy, wherein the electrode array is independently movable relative to the compliant balloon; (b) isolating the target tissue such that at least one electrode of the electrode array is in contact with the target tissue; and (c) delivering the ablation energy to those electrodes of the electrode array that are confirmed, using the visualization device, to be in contact with target tissue.

公开(公告)号：US20220249164A1

公开(公告)日：2022-08-11

申请号：US17590950

申请日：2022-02-02

申请人： CardioFocus, Inc.

发明人： Gerald Melsky ,  Lincoln Baxter ,  Omar Colon

IPC分类号： A61B18/24 ,  A61L29/08 ,  A61L29/06

摘要： An ablation catheter that includes a shaft having a distal end and a balloon coupled to the shaft. The balloon has an inner surface and an opposite outer surface. The inner surface has a proximal region including a proximal balloon end, a main center region, and a distal region including a distal balloon end. The ablation catheter also includes an energy emitter disposed inside the balloon and being configured to move both axially and rotationally within the inside of the balloon. The ablation catheter includes a thermally resistant coating disposed along the inner surface of the balloon within at least the main center region of the inner surface of the balloon. The thermally resistant coating is formed of a material selected from a group consisting of: silicone rubber, polyisoprene, polyurethane.

公开(公告)号：US08444639B2

公开(公告)日：2013-05-21

申请号：US13353086

申请日：2012-01-18

申请人： Jeffrey M. Arnold ,  Edward L. Sinofsky ,  Lincoln S. Baxter ,  Norman E. Farr

发明人： Jeffrey M. Arnold ,  Edward L. Sinofsky ,  Lincoln S. Baxter ,  Norman E. Farr

IPC分类号： A61B18/12

CPC分类号： A61B18/24 ,  A61B18/245 ,  A61B2017/00057 ,  A61B2017/00061 ,  A61B2018/0097 ,  A61B2018/2261 ,  A61B2018/2266 ,  A61B2018/2272 ,  A61B2090/065 ,  A61L2/10 ,  A61L29/085 ,  A61N7/02 ,  C08L27/12

摘要： A cardiac ablation instrument capable of removing blood from a treatment area is provided. The instrument includes a catheter configured to deliver a distal end thereof to a patient's heart. The instrument can also include an expandable element coupled to the distal end of the catheter wherein the expandable member is configured to be positioned adjacent a target area thereby defining a treatment area between the expandable member and the target area. Further, the instrument can include an irrigation mechanism configured to dispense an irrigation fluid from the catheter thereby displacing blood from the treatment area. Additionally, the instrument includes an energy emitter configured to deliver energy to tissue within the treatment area. The instrument can also include a contact sensor configured to determine the presence of such blood within the treatment area. Methods for ablating tissue are also provided.

摘要翻译： 提供能够从治疗区域去除血液的心脏消融器械。 仪器包括被配置为将其远端递送到患者心脏的导管。 仪器还可以包括耦合到导管的远端的可扩张元件，其中可扩张构件构造成邻近目标区域定位，从而限定可扩张构件和目标区域之间的治疗区域。 此外，仪器可以包括配置成从导管分配冲洗流体的冲洗机构，从而从处理区域移出血液。 另外，该仪器包括能量发射器，其配置成将能量传递到处理区域内的组织。 仪器还可以包括被配置为确定处理区域内这种血液的存在的接触传感器。 还提供了消融组织的方法。

公开(公告)号：US20110082450A1

公开(公告)日：2011-04-07

申请号：US12895987

申请日：2010-10-01

申请人： Gerald Melsky ,  Brian Estabrook ,  Alfred Stancampiano

发明人： Gerald Melsky ,  Brian Estabrook ,  Alfred Stancampiano

IPC分类号： A61B18/18

CPC分类号： A61B18/24 ,  A61B34/25 ,  A61B2017/00243 ,  A61B2017/22059 ,  A61B2018/00982 ,  A61B2018/2025 ,  A61B2018/2266 ,  A61B2018/2272 ,  A61B2090/306 ,  A61B2090/3614

摘要： A cardiac tissue ablation system includes an elongate catheter configured to deliver a distal end thereof to a patient's heart and an expandable member formed at the distal portion of the catheter. The expandable member has an elastic portion configured to conform to the shape of a target tissue region upon expansion. The expandable member has a plurality of inflation settings that correspond to different levels of inflation of the expandable member. The system also includes a controller for selecting an inflation setting for the expandable member and an energy emitter movably disposed within a lumen of the catheter. The energy emitter is configured to deliver radiant ablative energy to the target tissue region.

摘要翻译： 心脏组织消融系统包括细长导管，其构造成将其远端输送到患者的心脏，以及形成在导管的远端部分处的可扩张构件。 可膨胀构件具有弹性部分，其构造成在膨胀时符合目标组织区域的形状。 可膨胀构件具有对应于可膨胀构件的不同膨胀水平的多个充气设定。 该系统还包括用于选择用于可膨胀构件的膨胀设定的控制器和可移动地设置在导管内腔内的能量发射器。 能量发射器被配置为向目标组织区域传递辐射消融能量。

公开(公告)号：US20080195088A1

公开(公告)日：2008-08-14

申请号：US12102466

申请日：2008-04-14

申请人： Norman E. Farr ,  William E. Wieler

发明人： Norman E. Farr ,  William E. Wieler

IPC分类号： A61B18/18

CPC分类号： A61B18/245 ,  A61B2017/00061 ,  A61B2018/0097 ,  A61B2018/2266 ,  A61B2018/2272 ,  A61B2090/065

摘要： Methods and apparatus are disclosed for forming annular lesions in tissue. The methods include introduction of an optical apparatus proximate to a tissue site, via, for example, a catheter. The optical apparatus includes a pattern-forming optical wave guide in communication with a light transmitting optical fiber. Energy is transmitted through the optical fiber, such that radiation is propagated through the optical fiber and the wave guide projects an annular light pattern, e.g., a circle or a halo.

摘要翻译： 公开了用于在组织中形成环形损伤的方法和装置。 这些方法包括通过例如导管引入靠近组织部位的光学装置。 光学装置包括与光传输光纤连通的图案形成光波导。 能量通过光纤传输，使得辐射通过光纤传播，并且波导引出环形光图案，例如圆形或光晕。

公开(公告)号：US20050222558A1

公开(公告)日：2005-10-06

申请号：US11062906

申请日：2005-02-22

申请人： Lincoln Baxter ,  Jeffrey Arnold ,  Gerald Melsky

发明人： Lincoln Baxter ,  Jeffrey Arnold ,  Gerald Melsky

IPC分类号： A61B17/22 ,  A61B18/02 ,  A61B18/04 ,  A61B18/14 ,  A61B18/18 ,  A61B18/20 ,  A61B18/24 ,  A61N7/02

CPC分类号： A61B18/1492 ,  A61B18/24 ,  A61B2017/22051 ,  A61B2018/00214 ,  A61B2018/0022 ,  A61B2018/00285 ,  A61B2018/00375 ,  A61B2018/0262 ,  A61N7/02

摘要： The present invention provides devices and methods for the treatment of atrial fibrillation. In one embodiment method for treatment of atrial fibrillation is provided that includes positioning a sheath catheter having a deflectable distal end segment in the left atrium of a heart, orienting said sheath catheter such that an ablation instrument can be delivered through the sheath catheter to a position proximal to a first pulmonary vein, activating the ablation instrument to form a circumferential lesion around the first pulmonary vein, repositioning the sheath catheter by deflecting the distal end segment to another orientation, and activating the ablation instrument to form a circumferential lesion around at least one additional pulmonary vein.

摘要翻译： 本发明提供了用于治疗房颤的装置和方法。 在一个实施方案中，提供了一种用于治疗心房颤动的方法，其包括将具有可偏转的远端段的护套导管定位在心脏的左心房中，定向所述护套导管，使得消融器械可以通过护套导管递送到位置 接近第一肺静脉，激活消融器械以形成围绕第一肺静脉的周围损伤，通过将远端段偏转到另一取向来重新定位鞘导管，并激活消融器械以形成围绕至少一个的周围损伤 额外的肺静脉。

公开(公告)号：US20040147912A1

公开(公告)日：2004-07-29

申请号：US10756660

申请日：2004-01-13

申请人： CARDIOFOCUS, INC.

发明人： Edward L. Sinofsky

IPC分类号： A61B018/24

CPC分类号： A61B18/22 ,  A61B18/1492 ,  A61B18/24 ,  A61B2017/00057 ,  A61B2017/00243 ,  A61B2017/22058 ,  A61B2017/22059 ,  A61B2018/00577 ,  A61B2018/00642 ,  A61B2018/00839 ,  A61B2018/2238 ,  A61B2018/2261 ,  A61B2018/2272 ,  A61B2018/2288 ,  A61M25/0105 ,  A61N7/02

摘要： An apparatus and method are disclosed for ablation of diseased tissue. The method includes introducing a flexible elongate member into a predetermined tissue site with a flexible elongate member having a proximal end, a distal end and a longitudinal first lumen extending therebetween. A slidable conductor is positioned through the lumen proximate to the tissue site and energy is transmitted to the distal end of the elongate member through the conductor. A deflection member fixedly attached to the distal end of the elongate member can be manipulated to cause the distal end of the elongate member to bend. The target tissue is ablated, coagulated or photochemically modulated without damaging surrounding tissue. The apparatus can be energy transparent and include deflection members to manipulate distal portions of the apparatus. Suitable types of energy for ablation include ultrasound and laser energy.

公开(公告)号：US06159203A

公开(公告)日：2000-12-12

申请号：US568348

申请日：1990-08-15

申请人： Edward Lawrence Sinofsky

发明人： Edward Lawrence Sinofsky

IPC分类号： A61B18/20 ,  A61B18/24 ,  A61B19/00 ,  G02B6/42 ,  A61N5/06

CPC分类号： A61B18/24 ,  G02B6/4296 ,  A61B2018/2065 ,  A61B90/39

摘要： Laser energy produced by a laser operating in the mid-infrared region (approximately 2 micrometers) is delivered by an optical fiber in a catheter to a surgical site for biological tissue removal and repair. Disclosed laser sources which have an output wavelength in this region include: Holmium-doped Yttrium Aluminum Garnet (Ho:YAG), Holmium-doped Yttrium Lithium Fluoride (Ho:YLF), Erbium-doped YAG, Erbium-doped YLF and Thulium-doped YAG. For tissue removal, the lasers are operated with relatively long pulses at energy levels of approximately 1 joule per pulse. For tissue repair, the lasers are operated in a continuous wave mode at low power. Laser output energy is applied to a silica-based optical fiber which has been specially purified to reduce the hydroxyl-ion concentration to a low level. The catheter may be comprised of a single optical fiber or a plurality of optical fibers arranged to give overlapping output patterns for large area coverage.

公开(公告)号：US11484692B2

公开(公告)日：2022-11-01

申请号：US17024269

申请日：2020-09-17

申请人： CardioFocus, Inc.

发明人： Sergei Babko-Malyi ,  Brian Estabrook ,  Gerald Melsky ,  Richard Thompson

IPC分类号： A61M25/10

摘要： A method for maintaining a balloon of a balloon catheter at a prescribed pressure of between about 0.2 psi and 1 psi comprises the step of: generating a vacuum within a reservoir defined in a burette that is part of a fluid management system that is configured to controllably inflating and deflating the balloon by circulating balloon fill media along a fluid circuit, wherein generating the vacuum results in formation of a pressure differential along the fluid circuit, thereby allowing the balloon to be maintained at the prescribed pressure between about 0.2 psi and about 1 psi.

公开(公告)号：US11413089B2

公开(公告)日：2022-08-16

申请号：US16578295

申请日：2019-09-21

申请人： CardioFocus, Inc.

发明人： Omer Peled ,  Anthony Jason Mirabito

IPC分类号： A61B18/12 ,  A61B18/14 ,  A61B18/24 ,  A61B18/02 ,  A61B18/20 ,  A61B18/22 ,  A61B18/00 ,  A61B5/0538 ,  A61F7/12

摘要： A catheter device provides a balloon structure and a side-firing laser lumen within the balloon to create lesions in the pulmonary vein (PV) in the treatment of atrial fibrillation. Mounted on the balloon so as to contact the PV when the balloon is inflated are one or more electrodes which may be used in a measurement mode, a treatment mode, or both.