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公开(公告)号：US11484191B2
公开(公告)日：2022-11-01
申请号：US16160542
申请日：2018-10-15
摘要： A surgical system for performing a surgical procedure includes an ex-vivo positioning mechanism and an in-vivo instrument magnetically attracted to the ex-vivo positioning mechanism. The in-vivo instrument can be positioned within a patient by moving the ex-vivo positioning mechanism. In addition, the surgical system includes a percutaneous member introducible into the patient independent from the ex-vivo positioning mechanism, the percutaneous member comprising a connector at a distal end thereof, wherein the connector is selectively couplable to the in-vivo instrument within the patient.
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公开(公告)号：US11000277B2
公开(公告)日：2021-05-11
申请号：US14848572
申请日：2015-09-09
IPC分类号： A61B17/068 , B65B55/18 , B65B5/04 , B65B55/16 , A61B17/32 , A61B17/10 , A61B17/072 , A61B17/00 , A61B17/295 , A61B34/00 , A61B50/36 , A61B90/98 , A61B90/00 , A61B17/122 , A61B17/29 , A61B34/30 , A61B34/20
摘要： A surgical instrument, such as an endoscopic or laparoscopic instrument. The surgical instrument may comprise an end effector comprising at least one sensor. The surgical instrument may also comprise an electrically conductive shaft having a distal end connected to the end effector wherein the sensor is electrically insulated from the shaft. The surgical instrument may also comprise a handle connected to a proximate end of the shaft. The handle may comprise a control unit electrically coupled to the shaft such that the shaft radiates signals as an antenna from the control unit to the sensor and receives radiated signals from the sensor. Other components electrically coupled to the shaft may also radiate the signals.
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公开(公告)号：US10729732B2
公开(公告)日：2020-08-04
申请号：US16669143
申请日：2019-10-30
申请人： Ethicon Endo-Surgery, Inc. , The General Hospital Corporation , President and Fellows of Harvard College
摘要： Methods and compositions are provided for treating weight related conditions and metabolic disorders by altering microbiota in a subject. One aspect provides methods and compositions to alter microbiota in a subject by administering to the subject a composition that includes a substantially purified microbiota from phyla such as Bacteroidetes, Proteobacteria, Firmicutes and Verrucomicrobia or orders such as Bacteroidales, Verrucomicrobiales, Clostridiales and Enterobacteriales or genera such as Alistipes, Clostridium, Escherichia, and Akkermansia. Another aspect includes a pharmaceutical composition for altering microbiota that includes a therapeutically effective amount of substantially purified microbiota and a pharmaceutically acceptable carrier. Yet another aspect includes methods for treating a disorder, such as obesity, in a subject in need of such treatment by changing relative abundance of microbiota in a gastrointestinal tract of the subject without or in addition to a surgical procedure.
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公开(公告)号：US10687808B2
公开(公告)日：2020-06-23
申请号：US16377533
申请日：2019-04-08
IPC分类号： A61B17/072 , A61B90/00 , A61B17/068 , A61B17/00 , A61B17/30 , A61B17/29
摘要： Devices and methods are provided for forming and securing a tissue plication. More particularly, the devices and methods of the present invention can be used to create multiple tissue folds on an anterior and posterior wall of a stomach cavity to reduce the volume thereof. In one aspect, a method of gastric volume reduction is disclosed that includes advancing a tissue acquisition and fixation device endoscopically into a stomach, manipulating the device to form a first fold of tissue on an interior surface of an anterior wall of the stomach, and manipulating the device to form a second fold of tissue on an interior surface of a posterior wall of the stomach, where the second fold is not attached to the first fold.
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公开(公告)号：US10441808B2
公开(公告)日：2019-10-15
申请号：US13977536
申请日：2011-12-21
申请人： Jason L. Harris , Lee M. Kaplan , David N. Plescia , Taylor W. Aronhalt , James W. Voegele , Nicholas Stylopoulos
发明人： Jason L. Harris , Lee M. Kaplan , David N. Plescia , Taylor W. Aronhalt , James W. Voegele , Nicholas Stylopoulos
摘要： Methods and devices are provided for activating brown adipose tissue (BAT) with light. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a medical device is provided that activates BAT by using light to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The light can be configured to directly or indirectly stimulate the nerves and/or the brown adipocytes. The light can be configured to indirectly stimulate the nerves and/or the brown adipocytes by activating a light activatable medium administered to a patient and configured to respond to the light to cause activation of the brown adipose tissue.
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公开(公告)号：US10342544B2
公开(公告)日：2019-07-09
申请号：US15161512
申请日：2016-05-23
发明人： Gregory J. Bakos , Mark S. Zeiner
摘要： An apparatus is operable to provide an anastomosis coupling two hollow organs, such as a duodenum and ileum. The apparatus includes a first component that is inserted through an enterotomy in a first hollow organ and a second component that is inserted through an enterotomy in a second hollow organ. The first and second components are brought together to o align the enterotomies and compress apposed layers of tissue adjacent to the enterotomies. The compressed tissue eventually necroses and the apparatus may be removed or simply pass through the hollow organ. Each component may include a set of pivoting links and a resilient member that is configured to both bias the links to an expanded configuration and grip the tissue adjacent to the enterotomy. The components may include magnets that secure the positioning of the components relative to each other and provide a compressive force on the apposed tissue.
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公开(公告)号：US10242756B2
公开(公告)日：2019-03-26
申请号：US14983083
申请日：2015-12-29
发明人： Jason L. Harris , Christopher J. Hess , Nitin Kumar Jain , Diane M. Francis , Thomas E. Albrecht , Tina Denise Hunter
摘要： Various systems and methods for predicting metabolic and bariatric surgery outcomes are provided. The systems and methods can also provide predictions for non-surgical metabolic and bariatric treatments. In general, a user can receive predictive outcomes of multiple bariatric procedures that could be performed on a patient. In one embodiment, a user can electronically access a metabolic and bariatric surgery outcome prediction system, e.g., using one or more web pages. The system can provide predictive outcomes of one or more different bariatric surgeries for the patient based on data gathered from the user and on historical data regarding outcomes of the different bariatric surgeries. The system can additionally provide predictive outcomes for not having any treatment and/or a comparison of the predictive outcomes of the one or more different bariatric surgeries to the predictive outcomes for not having any treatment.
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公开(公告)号：US10105144B2
公开(公告)日：2018-10-23
申请号：US14547725
申请日：2014-11-19
发明人： Chad P. Boudreaux , Mark S. Ortiz
IPC分类号： A61B17/10 , A61B17/128 , A61B17/064 , A61B17/122 , A61B17/072 , A61B17/00 , A61B90/00
摘要： A surgical clip is provided for ligating or transecting tissue, such as vessels, other tubular ducts, and the like and a surgical clip applier device for delivering and applying the surgical clip to the tissue. The surgical clip can include a spine and opposed arms extending from the spine where the arms can define a clamping length. In a resting state, the clip can be biased to a closed position such that the ends of each opposed arm are disposed in proximity to each other. With such biasing, when applied to a tissue, such as with a surgical clip applier, the clip can exert a positive clamping pressure to the tissue along the clamping length to seal the tissue and limit passage of fluids, such as blood, from the tissue.
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公开(公告)号：US10080565B2
公开(公告)日：2018-09-25
申请号：US14697659
申请日：2015-04-28
发明人： Alessandro Pastorelli , Michael A. Murray , William Bruce Weisenburgh, II , Federico Bilotti , Laszlo Csiky , Todd Phillip Omaits
IPC分类号： A61B17/04 , A61B17/10 , A61B17/11 , A61B17/115 , A61B17/068 , A61B17/3205
CPC分类号： A61B17/105 , A61B17/068 , A61B17/1114 , A61B17/115 , A61B17/32053
摘要： A surgical stapling instrument (1) comprises a staple fastening assembly (4) in the distal region of said instrument, the staple fastening assembly (4) including a cartridge device (8) which comprises at least one closed row (17, 18) of staples and defines a wavy distal end surface (14), and an anvil (9) which defines a wavy proximal staple forming surface (20) substantially matching the distal end surface (14) and which is adapted to cooperate with the cartridge device (8) for forming the ends of the staples exiting from the cartridge device (8), wherein the distal end surface (14) and the staple forming surface (20) have a globally wavy shape including two opposite peaks (21) and two opposite valleys (22) angularly spaced at about 90° from the adjacent peaks (21) and in that said two-peaks-two-valleys wavy shape is formed by a stepped configuration of said surfaces (14, 20).
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公开(公告)号：US09788885B2
公开(公告)日：2017-10-17
申请号：US15046917
申请日：2016-02-18
发明人： Gary L. Long , Gregory J. Bakos , David N. Plescia
CPC分类号： A61B18/1206 , A61B18/1492 , A61B2018/00613 , A61B2018/00791 , A61B2018/00815 , A61B2018/00982 , A61B2018/126
摘要： An energy source for use with an electrosurgical system is disclosed. In one embodiment, the energy source includes a power supply, one or more capacitors coupled to the power supply, and a switching component coupled to the one or more capacitors. The switching component is configured to output pulses of a biphasic waveform. The pulses are capable of treating undesired tissue by inducing a change in voltage potential across cell membranes of a plurality of cells in the undesired tissue to promote non-thermal cell death in the plurality of cells. The pulses are also capable of treating the undesired tissue with no or minimal muscle contractions in patient tissue within reach of the biphasic waveform during treatment of the undesired tissue.
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