公开(公告)号：US20080161381A1

公开(公告)日：2008-07-03

申请号：US11568283

申请日：2006-08-04

申请人： Klaus Wessel

发明人： Klaus Wessel

IPC分类号： A61K31/385 ,  A61P15/10

CPC分类号： A61K31/198 ,  A61K31/385

摘要： The present invention relates to solid compositions comprising a substance which improves nitric oxide (NO) availability, re. an NO donor or a precursor of the biosynthesis of nitric oxide or an direct or indirect NO agonist, with arginine being a preferred compound, in combination with a dithiolane, with α-lipoic acid as a preferred compound, and its use for improvement of sexual function. The compositions according to the invention comprise the NO donor or its precursor in excess, based on the molar amount of the constituents. The compositions are also suited for the improvement of sexual function. In particular the present invention relates to the use of a dithiolane in combination with a NO donor or a precursor thereof for the preparation of a medication for treatment of sexual dysfunction.

摘要翻译： 本发明涉及包含改善一氧化氮（NO）可用性的物质的固体组合物， NO供体或一氧化氮或直接或间接NO激动剂的生物合成的前体，其中精氨酸是优选的化合物，与二硫戊环组合，与α-硫辛酸作为优选的化合物，其用于改善性 功能。 根据本发明的组合物基于组分的摩尔量包含NO供体或其前体过量。 该组合物也适用于改善性功能。 特别地，本发明涉及二硫戊环与NO供体或其前体组合用于制备用于治疗性功能障碍的药物的用途。