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公开(公告)号：US10370649B2
公开(公告)日：2019-08-06
申请号：US15317039
申请日：2015-06-17
摘要： The present invention relates to the field of nucleic acid collection and storage, and in particular to the collection and long-term storage of nuclei. The invention provides a device and method which can be used to capture and store nuclei at ambient temperatures allowing the subsequent isolation of nucleic acids by passive washing with a wash buffer. The present invention also provides a kit including the device of the invention suitable for carrying out the method of the invention.
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公开(公告)号：US10227554B2
公开(公告)日：2019-03-12
申请号：US15529567
申请日：2015-12-15
IPC分类号： C12M1/00
摘要： The invention relates to devices, methods and systems for collecting and solidifying waste material from bioreactor cell cultures in order to facilitate waste disposal. The invention finds particular utility in mammalian cell culture applications. A transverse wall divides the interior of a waste bag into two chambers, the first chamber containing an inlet receiving waste liquid from a bioreactor, the second chamber containing an absorbent material to solidify the liquid into a gel. The transverse wall acts to direct the flow of waste media into the second chamber where it is converted into a gel and further prevents the inlet from being blocked by any gel or particulate materials. Methods and uses regarding this invention are described.
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公开(公告)号：US10196675B2
公开(公告)日：2019-02-05
申请号：US15175478
申请日：2016-06-07
IPC分类号： C12Q1/00 , C12Q1/6806 , A01N1/02 , C12N9/22 , C12N9/96
摘要： This invention relates to flat solid media for the storage of samples of biological materials and methods of analyzing biomolecules contained within the samples following storage. In particular, the invention relates to the storage and further analysis of biomolecules present in the biological materials, such as proteins, enzymes and nucleic acids. The invention finds particular utility in the dry, room temperature storage of biological materials.
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4.发明授权公开(公告)号：US10085726B2
公开(公告)日：2018-10-02
申请号：US15101113
申请日：2014-11-25
发明人： Cheryl Louise Potts , Peter James Tatnell , Geraint Seymour , Alan Stuart Pierce , Michael John Smith , Samantha Jane Ogden , Neil John Williams , Christopher Burrows , Jared William Harris Evans , Ashley Edward Bryant , Sean Robert Sweeney
摘要： A controlled transfer biological sample material collection device is disclosed which comprises: a body; and a sample collection member for collecting the biological sample material (not shown), the body housing a sample storage medium for generally dry storage of the biological material, the collection member being moveable from an exposed position (shown in FIG. 8) where collection of a biological sample is possible, to a transfer position (shown in FIG. 9) which effects transfer of at least a portion of the collected sample to said medium. The device is characterized in that the body slideably supports the sample collection member, and in that the body or collection member include a ramp-like projection portion (116 FIG. 10) operable to force the collection member into the transfer position against the medium and to effect said transfer as the collection member slides within the body.
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公开(公告)号：US09926525B2
公开(公告)日：2018-03-27
申请号：US14767141
申请日：2014-02-10
CPC分类号： C12M23/48 , C12M23/02 , C12M23/28 , C12M23/44 , C12M23/52 , C12M27/02 , C12M29/00 , C12M41/12
摘要： The present invention relates to systems and methods for optimising the usage of laboratory and cell culturing space for cell culture and biomanufacturing. The invention provides a system and method that can be used to provide a plurality of workstations and/or storage bays for bioreactors in cell culturing and/or biomanufacturing facilities.
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公开(公告)号：US09810609B2
公开(公告)日：2017-11-07
申请号：US14765009
申请日：2014-01-28
CPC分类号： G01N1/286 , C12M45/22 , C12N15/1003 , C12Q1/6806
摘要： Apparatus for transferring biological material onto storage media, said apparatus comprising a powered hand held device including a powered hammer arrangement, the apparatus further comprising an anvil arrangement and a storage media accepting area between the hammer and the anvil, the apparatus being operable such that in use the storage media is repeatedly compressed between the hammer and the anvil by blows from the hammer.
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公开(公告)号：US09382577B2
公开(公告)日：2016-07-05
申请号：US14374270
申请日：2013-01-31
CPC分类号： C12Q1/6806 , G01N1/02 , G01N2001/007 , G01N2001/028
摘要： Disclosed is a device (10) for collecting a biological sample, the device comprising an elongate handle (40) extending generally along a handle axis, and a sample collecting head (20) removably supported or supportable on the handle, the head being formed from a porous folded planar or sheet material, optionally including a plurality of arms (22-28 FIG. 2) each extending away from the handle axis in a different direction. An ejection handle is provided. Disclosed also is an efficient method for extracting DNA information from the device.
摘要翻译： 公开了一种用于收集生物样品的装置（10），该装置包括大致沿着手柄轴线延伸的细长手柄（40）和可移除地支撑或支撑在手柄上的样本收集头（20），头部由 多孔折叠的平面或片状材料，可选地包括多个臂（22-28图2），每个臂在不同的方向上远离手柄轴线延伸。 提供弹出手柄。 还公开了从装置中提取DNA信息的有效方法。
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公开(公告)号：US09329112B2
公开(公告)日：2016-05-03
申请号：US13982312
申请日：2012-01-25
CPC分类号： G01N1/42 , B01L3/508 , B01L2200/0647 , B01L2200/16 , B01L2300/06 , B01L2300/0829 , B01L2300/0832 , Y10T436/2525
摘要： A container holding, and a method of storing, freeze-dried biological samples. The container includes a chamber having an upper portion and a lower portion. The chamber includes a wall, and the lower portion of the chamber is fluidly connected to the upper portion of the chamber such that, when liquid is received at the upper portion, the received liquid can pass to and accumulate in the lower portion. Further, the freeze-dried material is located in the lower portion, and the container includes a physical structure in the form of a stop protruding inwards from the wall, the physical structure being for inhibiting the freeze-dried material from moving from the lower portion of the chamber to the upper portion of the chamber.
摘要翻译： 容器的容器，以及冷冻干燥的生物样品的储存方法。 容器包括具有上部和下部的腔室。 腔室包括壁，腔室的下部流体地连接到腔室的上部，使得当液体在上部被容纳时，所接收的液体可以传递并且积聚在下部。 此外，冷冻干燥材料位于下部，容器包括从壁向内突出的止挡件形式的物理结构，该物理结构用于抑制冻干材料从下部移动 的腔室的上部。
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公开(公告)号：US09157079B2
公开(公告)日：2015-10-13
申请号：US13832139
申请日：2013-03-15
发明人： Hugh O'Malley , Barry Johnson
CPC分类号： C12N15/1006 , C07H21/00 , C12N15/1017
摘要： The present invention relates to a method for storage and subsequent lysis of a sample in which the sample is immobilized on a solid support. The solid matrix is embedded with a low concentration of both a chaotropic salt and a surfactant which act synergistically to efficiently store and lyse a biological sample.
摘要翻译： 本发明涉及将样品固定在固体支持物上的样品的储存和随后裂解的方法。 固体基质嵌入低浓度的离液盐和表面活性剂，其协同作用以有效地储存和裂解生物样品。
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