Prodrugs for the improved delivery of halogen-containing
glucocorticosteroids
    1.
    发明授权
    Prodrugs for the improved delivery of halogen-containing glucocorticosteroids 失效
    用于改善输送含卤素糖皮质激素的前药

    公开(公告)号:US4279900A

    公开(公告)日:1981-07-21

    申请号:US61177

    申请日:1979-07-27

    IPC分类号: C07J33/00 C07J71/00

    摘要: Novel 3,2'-spiro(1',3'-thiazolidine) compounds which are transient prodrug forms of known 6- and/or 9-haloglucocorticosteroids are described. The subject prodrugs provide improved delivery of the prior art steroids for therapeutic purposes, particularly in alleviating inflammation, and can be prepared by known methods, for example, by reacting the corresponding 3-keto steroids with a thiazolidine forming reagent such as an L-cysteine alkyl ester.

    摘要翻译: 描述了已知的6-和/或9-卤素糖皮质激素的瞬时前药形式的新型3,2'-螺(1',3'-噻唑烷)化合物。 本发明的前药提供了用于治疗目的的现有技术类固醇的改进递送,特别是在减轻炎症中,并且可以通过已知方法制备,例如通过使相应的3-酮类固醇与形成噻唑烷的试剂例如L-半胱氨酸 烷基酯。

    System for selecting the tracking technique for tracking a user device based on user device proximity to location beacons

    公开(公告)号:US11835635B2

    公开(公告)日:2023-12-05

    申请号:US17511941

    申请日:2021-10-27

    申请人: Intrex

    发明人: Ted Tzirimis

    IPC分类号: G01S19/48 G01S19/46 G01S19/45

    CPC分类号: G01S19/48 G01S19/46 G01S19/45

    摘要: A computer-implemented method includes: selecting between a first location tracking technique and a second location tracking technique used to track a user device. The selecting includes: receiving a communications signal emitted from the user device via one or more network devices; selecting the first tracking location technique based on receiving the communications signal; determining that the user device is outside communications range of the one or more network devices; and selecting the second tracking location technique based on the determining that the user device is outside communications range of the one or more network devices. The method further includes monitoring location information of the user device based on the selecting between the first location tracking technique and the second location tracking technique; and storing or outputting the location information.

    SYSTEM FOR TRACING REGISTERED AND NON-REGISTERED DEVICES

    公开(公告)号:US20210400440A1

    公开(公告)日:2021-12-23

    申请号:US17352955

    申请日:2021-06-21

    申请人: Intrex

    发明人: Ted Tzirimis

    摘要: A computer-implemented method includes: receiving, by a computing device, a first type of communication signal data object comprising an identifier of a registered user device, an identifier of a network device, and a measure of signal strength of a communication signal emitted by the registered user device and received by the network device; determining, by the computing device, a location of the registered used device based on a known location of the network device and the measure of the signal strength; generating, by the computing device, a first location data record identifying the determined location of the registered used device and a user registered to the registered user device; and storing or outputting, by the computing device, the first location data record.

    SYSTEM FOR SELECTING THE TRACKING TECHNIQUE FOR TRACKING A USER DEVICE BASED ON USER DEVICE PROXIMITY TO LOCATION BEACONS

    公开(公告)号:US20220128710A1

    公开(公告)日:2022-04-28

    申请号:US17511941

    申请日:2021-10-27

    申请人: Intrex

    发明人: Ted Tzirimis

    IPC分类号: G01S19/48

    摘要: A computer-implemented method includes: selecting between a first location tracking technique and a second location tracking technique used to track a user device. The selecting includes: receiving a communications signal emitted from the user device via one or more network devices; selecting the first tracking location technique based on receiving the communications signal; determining that the user device is outside communications range of the one or more network devices; and selecting the second tracking location technique based on the determining that the user device is outside communications range of the one or more network devices. The method further includes monitoring location information of the user device based on the selecting between the first location tracking technique and the second location tracking technique; and storing or outputting the location information.

    Rules-based area access management system using personal area networks

    公开(公告)号:US11495071B2

    公开(公告)日:2022-11-08

    申请号:US17162312

    申请日:2021-01-29

    申请人: Intrex

    发明人: Ted Tzirimis

    IPC分类号: G07C9/00 G07C9/27

    摘要: A computer-implemented method, a system that performs the computer-implemented method, and a computer program product that stores instructions to perform the computer-implemented method are disclosed. The computer-implemented includes receiving a device ID and a door ID; retrieving a dynamic set of access rules for the door ID; determining whether the device ID is authorized based on the dynamic set of access rules; outputting an indication indicating that the device ID is authorized to effectuate unlocking or opening of a door associated with the door ID; outputting an indication indicating that the device ID is not authorized to prevent unlocking or opening of the door.

    RULES-BASED AREA ACCESS MANAGEMENT SYSTEM USING PERSONAL AREA NETWORKS

    公开(公告)号:US20210241554A1

    公开(公告)日:2021-08-05

    申请号:US17162312

    申请日:2021-01-29

    申请人: Intrex

    发明人: Ted Tzirimis

    IPC分类号: G07C9/00 G07C9/27

    摘要: A computer-implemented method, a system that performs the computer-implemented method, and a computer program product that stores instructions to perform the computer-implemented method are disclosed. The computer-implemented includes receiving a device ID and a door ID; retrieving a dynamic set of access rules for the door ID; determining whether the device ID is authorized based on the dynamic set of access rules; outputting an indication indicating that the device ID is authorized to effectuate unlocking or opening of a door associated with the door ID; outputting an indication indicating that the device ID is not authorized to prevent unlocking or opening of the door.