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    Packaging system for tissue grafts
    1.
    发明授权
    Packaging system for tissue grafts 有权

    公开(公告)号：US11375710B2

    公开(公告)日：2022-07-05

    申请号：US16903663

    申请日：2020-06-17

    申请人： Musculoskeletal Transplant Foundation

    发明人： Kevin Wu ,  Elizabeth Ann Poyss ,  Todd Nilsen ,  Alison Ling

    IPC分类号： A01N1/02 ,  B65B25/00 ,  B65D33/01 ,  B65B9/02

    摘要： A tissue graft container is provided having an interior space and including a vent which allows fluid (liquid and vapor) to escape from the container during drying of the tissue graft. The vent may be one or more apertures, one or more elongated openings, or a combination thereof, through one or more components of the container. A tissue graft packaging system having a retainer including first and second members with respective first and second pluralities of channels, and configured to removeably interconnect the first and second members in a closed configuration. The first and second pluralities of channels create a continuous interior space. The retainer further includes a vent, such as apertures, slits, etc., through one or both of the first and second retainers, for allowing moisture to escape from the retainer during the drying of a tissue graft contained within the continuous interior space of the retainer.

    ACELLULAR SOFT TISSUE-DERIVED MATRICES AND METHODS FOR USING SAME
    3.
    发明申请
    ACELLULAR SOFT TISSUE-DERIVED MATRICES AND METHODS FOR USING SAME 有权

    公开(公告)号：US20220079994A1

    公开(公告)日：2022-03-17

    申请号：US17536841

    申请日：2021-11-29

    申请人： Musculoskeletal Transplant Foundation

    发明人： Yen-Chen Huang ,  Asia Ivery ,  Bryan Choi ,  Benjamin Schilling ,  Manh-Dan Ngo

    IPC分类号： A61K35/35 ,  A61L27/36

    摘要： Methods are provided for treatment of several conditions of one or more body features, where the method comprises implanting an acellular soft tissue-derived matrix in, on, proximate to, or a combination thereof, the body feature, wherein the acellular soft tissue-derived matrix comprises a delipidated, decellularized adipose matrix. The delipidated, decellularized adipose tissue matrix is produced by delipidating an adipose tissue sample, followed by decellularizing the delipidated adipose tissue sample. The resulting matrix contains a proportion of lipids which is less than the proportion of lipids contained in a matrix produced by decellularizing an adipose tissue sample prior to delipidating. The delipidated, decellularized adipose matrix may be provided as particles, a slurry, a paste, a gel, an injectable form, or in some other form.

    Asymmetric tissue graft
    4.
    发明授权
    Asymmetric tissue graft 有权

    公开(公告)号：US10945831B2

    公开(公告)日：2021-03-16

    申请号：US15173286

    申请日：2016-06-03

    申请人： MUSCULOSKELETAL TRANSPLANT FOUNDATION

    发明人： Antonio M. Bunce ,  Todd J. Nilsen ,  Evangelia Chnari ,  Aldona J. Spiegel ,  Michael Locarno ,  Gregory P. Adams

    IPC分类号： A61F2/12 ,  A61F2/10

    摘要： A dermal tissue allograft includes a dermal matrix having a profile including first and second vertices, a first imaginary axis extending between the first and second vertices, a first peripheral edge extending along a continuous path from the first vertex to the second vertex on a first side of the first imaginary axis, and a second peripheral edge extending along a continuous path from the first vertex to the second vertex on a second side of the first imaginary axis. The first peripheral edge includes an apogee, a convex portion, and a concave portion. The convex and concave portions meet at a transition point located on the first peripheral edge between its apogee and the second vertex. The second peripheral edge includes an apogee and is convex. The second perpendicular distance is greater than the first perpendicular distance. The dermal matrix has a substantially uniform thickness across its profile.

    Packaging system for tissue grafts
    6.
    发明授权
    Packaging system for tissue grafts 有权

    公开(公告)号：US10695157B2

    公开(公告)日：2020-06-30

    申请号：US15402806

    申请日：2017-01-10

    申请人： MUSCULOSKELETAL TRANSPLANT FOUNDATION

    发明人： Elizabeth Ann Poyss ,  Todd J. Nilsen ,  Alison Ling ,  Kevin Wu

    IPC分类号： A61F2/00 ,  A01N1/02 ,  B65B25/00 ,  B65B9/04

    摘要： A tissue graft packaging system having a retainer including first and second members with respective first and second pluralities of channel sidewalls that define first and second pluralities of channels, and first and second engagement means configured to removeably interconnect the first and second members. The first and second pluralities of channel sidewalls are configured to create a continuous interior space between the first and second members. A tissue graft, such as a cryopreserved viable tissue graft, is contained within the continuous interior space of the retainer. Processes for packaging, thawing and rinsing the tissue graft using the tissue graft packaging system and its retainer are also disclosed.