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公开(公告)号：US07846198B2
公开(公告)日：2010-12-07
申请号：US10342427
申请日：2003-01-13
申请人： Michael Hogendijk
发明人： Michael Hogendijk
CPC分类号： A61F2/88 , A61F2/91 , A61F2/95 , A61F2/966 , A61F2002/828 , A61F2220/0041 , A61F2220/0058 , A61F2230/0054 , A61F2250/0068
摘要： The present invention is directed to an implantable vascular prosthesis configured for use in a wide range of applications, such as treating aneurysms, maintaining patency in a vessel, and allowing for the controlled delivery of therapeutic agents to a vessel wall. The prosthesis comprises a helical proximal section coupled to a distal anchoring section having a generally zig-zag configuration. The prosthesis is configured to comply to a vessel wall without substantially remodeling the vessel, and further is configured to be precisely deployed in a vessel without shifting during deployment. The prosthesis also has a substantially small delivery profile compared to other known stents, while having an increased surface area to enhance delivery of therapeutic agents.
摘要翻译： 本发明涉及一种可植入血管假体，其被配置用于广泛的应用中，例如治疗动脉瘤，维持血管中的开放性，并允许将治疗剂控制递送到血管壁。 假体包括联接到具有大致Z字形配置的远侧锚固部分的螺旋近端部分。 假体构造成符合血管壁而不会使血管基本上重塑，并且进一步构造成在展开期间精确地展开在容器中而不发生变化。 与其他已知的支架相比，假体也具有相当小的输送轮廓，同时具有增加的表面积以增强治疗剂的递送。
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公开(公告)号：US20080221657A1
公开(公告)日：2008-09-11
申请号：US11716478
申请日：2007-03-09
IPC分类号： A61F2/84
CPC分类号： A61F2/885 , A61F2/91 , A61F2/95 , A61F2002/9505 , A61F2002/9511 , A61F2220/0058 , A61F2250/0039
摘要： A delivery system for an implantable vascular prosthesis is provided for a vascular prosthesis including at least first and second helical sections having alternating directions of rotation that are coupled to one another at apices. The delivery system includes an elongate body, a plurality of retainers and an outer sheath. The plurality of retainers are configured to temporarily retain a plurality of inner wound apices of the vascular prosthesis. The outer sheath is configured to retain the vascular prosthesis in a contracted state on the elongate body.
摘要翻译： 提供了一种用于可植入血管假体的输送系统，用于血管假体，其包括具有交替的旋转方向的至少第一和第二螺旋部分，其在顶点彼此连接。 输送系统包括细长体，多个保持器和外护套。 多个保持器构造成临时保持血管假体的多个内部缠绕顶点。 外护套构造成将细长体上的血管假体保持在收缩状态。
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公开(公告)号：US20060052861A1
公开(公告)日：2006-03-09
申请号：US11241341
申请日：2005-09-30
申请人： Eric Leopold , Tim Huynh
发明人： Eric Leopold , Tim Huynh
IPC分类号： A61F2/06
CPC分类号： A61F2/88 , A61F2/91 , A61F2/95 , A61F2/966 , A61F2002/828 , A61F2250/0067 , A61F2250/0068
摘要： The present invention is directed to an implantable vascular prosthesis configured for use in a wide range of applications, such as treating aneurysms, maintaining patency in a vessel, and providing controlled delivery of therapeutic agents to a vessel wall. The prosthesis comprises a helical body having a plurality of turns, wherein the proximal and distal edges of the turns of the prosthesis has a pattern that interdigitates when the prosthesis assumes the deployed configuration. The prosthesis optionally may comprise a radially expanding distal portion coupled to the helical body for facilitating placement of the prosthesis within a body vessel.
摘要翻译： 本发明涉及一种可植入血管假体，其配置用于广泛的应用中，例如治疗动脉瘤，维持血管中的开放性，以及提供治疗剂到血管壁的受控输送。 假体包括具有多个匝的螺旋体，其中假体的匝的近端和远端边缘具有当假体呈现展开构型时相互交叉的图案。 假体任选地可以包括联接到螺旋体的径向扩张的远侧部分，以便于将假体放置在体内容器内。
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公开(公告)号：US20050246008A1
公开(公告)日：2005-11-03
申请号：US10925756
申请日：2004-08-25
申请人： Michael Hogendijk , Eric Leopold , Tim Huynh , Miles Alexander
发明人： Michael Hogendijk , Eric Leopold , Tim Huynh , Miles Alexander
摘要： The present invention is directed to a delivery system for delivering a vascular prosthesis within a vessel, the vascular prosthesis having a contracted delivery configuration and a deployed configuration. The delivery system comprises a loader tube having a lumen preloaded with a delivery wire carrying a vascular prosthesis in the contracted delivery configuration. A separately inserted sheath includes a lumen configured to accept the vascular prosthesis, while retaining it in the contracted delivery configuration. The delivery wire is used to translate the vascular prosthesis to a distal end of the sheath for deployment in a vessel.
摘要翻译： 本发明涉及一种用于在血管内递送血管假体的输送系统，所述血管假体具有收缩的输送构型和展开构型。 递送系统包括装载管，其具有预先装载有在收缩递送构型中的血管假体的输送线的内腔。 单独插入的护套包括构造成接受血管假体的腔，同时将其保持在收缩的输送构型中。 输送线用于将血管假体平移到护套的远端以展开在血管中。
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公开(公告)号：US20130103130A1
公开(公告)日：2013-04-25
申请号：US13279724
申请日：2011-10-24
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2002/9517 , A61F2230/0019 , A61F2230/0091 , A61F2250/0018
摘要： A catheter assembly includes a catheter, including an inner member and a sheath, extending from a handle. The handle includes a housing, a braking assembly, a carriage and a carriage driver. The braking assembly comprises a braking element within the housing interior and a braking element rotator. The carriage comprises at least one carriage braking surface engaging the braking element. The carriage driver, such as a spring, biases the carriage towards the proximal end of the handle. The inner member has a proximal end secured to the housing. The sheath has a proximal end secured to the carriage. Rotating the braking element causes the carriage to move proximally as the carriage braking surface slides along the braking element. This causes the sheath to move proximally relative to the inner member.
摘要翻译： 导管组件包括从手柄延伸的包括内部构件和护套的导管。 手柄包括壳体，制动组件，滑架和滑架驱动器。 制动组件包括壳体内部的制动元件和制动元件旋转器。 滑架包括与制动元件接合的至少一个滑架制动表面。 诸如弹簧的滑架驱动器将滑架偏向手柄的近端。 内部构件具有固定到壳体的近端。 护套具有固定到托架的近端。 当滑架制动表面沿着制动元件滑动时，转动制动元件使滑架向近侧移动。 这使得护套相对于内部构件向近侧移动。
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公开(公告)号：US20080221658A1
公开(公告)日：2008-09-11
申请号：US11716512
申请日：2007-03-09
IPC分类号： A61F2/82
CPC分类号： A61F2/885 , A61F2/91 , A61F2220/0058
摘要： An implantable vascular prosthesis is provided for use in a wide range of applications wherein at least first and second helical sections having alternating directions of rotation are coupled to one another. The prosthesis is configured to conform to a vessel wall without substantially remodeling the vessel, and permits accurate deployment in a vessel without shifting or foreshortening.
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7.发明申请公开(公告)号：US20060004438A1
公开(公告)日：2006-01-05
申请号：US11154056
申请日：2005-06-15
申请人： Miles Alexander , Eric Leopold , David Chi
发明人： Miles Alexander , Eric Leopold , David Chi
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/88 , A61F2/91 , A61F2/915 , A61F2002/91525 , A61F2002/91533 , A61F2220/005 , A61F2220/0058 , A61F2230/0054
摘要： The present invention is directed to a prosthesis for treating an aneurysm, and delivery systems and methods therefor. The prosthesis includes a radially expanding distal section coupled to a helical section, the helical section including a localized feature configured to exclude or retard blood flow into an aneurysm. Methods of loading the prosthesis onto a specially-designed delivery system that facilitates proper orientation of the prosthesis within a target vessel, and methods of using the delivery system to deliver the prosthesis, also are provided.
摘要翻译： 本发明涉及一种用于治疗动脉瘤的假体及其输送系统及其方法。 所述假体包括联接到螺旋部分的径向扩张的远端部分，所述螺旋部分包括被配置为排除或阻止血液流入动脉瘤的局部特征。 还提供了将假体装载到促进假体在靶容器内的正确取向的专门设计的输送系统上的方法，以及使用输送系统输送假体的方法。
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8.发明申请Ribbon-type vascular prosthesis having stress-relieving articulation and methods of use 审中-公开具有应力消除关节的丝带型血管假体和使用方法公开(公告)号：US20040158314A1
公开(公告)日：2004-08-12
申请号：US10772840
申请日：2004-02-04
发明人： Michael Hogendijk
IPC分类号： A61F002/06
CPC分类号： A61F2/88 , A61F2/91 , A61F2/95 , A61F2/966 , A61F2002/828 , A61F2230/0054 , A61F2250/0068
摘要： A vascular prosthesis is provided having a self-expanding radial distal section joined to a ribbon-type helical section by a stress-relieving articulation. The stress-relieving articulation preferably comprises first and second connection members, each having a hinge and interconnected between the distal and helical sections, proximal ends of the first and second connection members also interconnected by a hinge, so that the articulation permits relatively independent rotation and compression of the distal and helical sections.
摘要翻译： 提供血管假体，其具有通过减轻压力的关节连接到带状螺旋部分的自扩张径向远端部分。 减轻应力的关节优选地包括第一和第二连接构件，每个连接构件具有铰链并且在远侧螺旋区段和螺旋区段之间互连，第一和第二连接构件的近端也通过铰链互连，使得铰接允许相对独立的旋转和 远端和螺旋段的压缩。
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公开(公告)号：US08348994B2
公开(公告)日：2013-01-08
申请号：US11716472
申请日：2007-03-09
申请人： Eric W. Leopold , Gerald Ray Martin , Michael Hogendijk , John Peckham , Mary Ann Parker, legal representative
IPC分类号： A61F2/06
CPC分类号： A61F2/95 , A61F2/885 , A61F2/91 , A61F2210/0076 , A61F2220/0058
摘要： An implantable vascular prosthesis is provided for use in a wide range of applications wherein at least first and second helical sections having alternating directions of rotation are coupled to one another. The prosthesis is configured to conform to a vessel wall without substantially remodeling the vessel, and permits accurate deployment in a vessel without shifting or foreshortening.
摘要翻译： 提供可植入血管假体用于广泛的应用，其中具有交替的旋转方向的至少第一和第二螺旋部分彼此联接。 假体构造成符合血管壁而不会使血管基本上重塑，并允许在血管内准确地展开而不需要移位或缩短。
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公开(公告)号：US20110218608A1
公开(公告)日：2011-09-08
申请号：US12879436
申请日：2010-09-10
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9511
摘要： A vascular prosthesis delivery system comprises a radially self expandable vascular prosthesis and a delivery sheath with a lumen with a smaller diameter storage region and a larger diameter delivery region. A prosthesis is housed within the storage region and is movable into the delivery region for delivery at a target site within a patient. The delivery force required to move the prosthesis from the delivery region into the patient can be less than the force required to move the prosthesis from the storage region into the delivery region. In some examples, the storage region defines a tapered lumen expanding in diameter in a distal direction. In some examples, the storage and delivery regions are generally coextensive and define a tapered lumen expanding in diameter in a distal direction. A method stores a vascular prosthesis in the storage region and delivers it to a target site from the delivery region.
摘要翻译： 血管假体递送系统包括径向自扩张血管假体和具有较小直径存储区域和较大直径递送区域的内腔的递送鞘。 假体容纳在存储区域内并且可移动到输送区域中以在患者体内的目标部位输送。 将假体从输送区域移动到患者中所需的输送力可以小于将假体从储存区域移动到输送区域中所需的力。 在一些示例中，存储区域限定在远端方向上直径膨胀的锥形腔。 在一些示例中，存储和传送区域通常是共同延伸的并且限定了在远端方向上直径膨胀的锥形腔。 一种方法将血管假体存储在存储区域中并将其从递送区域递送到目标部位。
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