Composition for protection against cell-damaging effects
    4.
    发明授权
    Composition for protection against cell-damaging effects 有权
    防止细胞损伤作用的组合物

    公开(公告)号:US09089548B2

    公开(公告)日:2015-07-28

    申请号:US14358365

    申请日:2012-11-15

    申请人: TIMA FOUNDATION

    发明人: Haruhiko Inufusa

    摘要: The present invention relates to a composition consisting of Vitamin C, L-glutamine, L-cystine or L-cysteine, riboflavin, succinic acid, fumaric acid, coenzyme Q10, and niacin. The present invention relates further to the use of the composition for minimizing the cell-damaging effect of radicals and harmful forms of oxygen, in particular of oxygen radicals or reactive oxygen species. The present invention relates to a composition comprising Vitamin C, L-glutamine, L-cystine or L-cysteine, riboflavin, succinic acid, fumaric acid, coenzyme Q10, and niacin, wherein the composition is administered in a concentration ranging from 10 to 20 mg/kg body weight. The present invention relates further to the composition for use in the treatment and/or prevention of radical and harmful forms of oxygen derived diseases, in particular of oxygen radical or reactive oxygen species derived diseases. The present invention relates further to the composition as a food supplement or dietary supplement.

    摘要翻译: 本发明涉及由维生素C,L-谷氨酰胺,L-胱氨酸或L-半胱氨酸,核黄素,琥珀酸,富马酸,辅酶Q10和烟酸组成的组合物。 本发明进一步涉及组合物的用途,以最大限度地减少自由基和有害形式的氧,特别是氧自由基或活性氧的细胞破坏作用。 本发明涉及包含维生素C,L-谷氨酰胺,L-胱氨酸或L-半胱氨酸,核黄素,琥珀酸,富马酸,辅酶Q10和烟酸的组合物,其中组合物以10至20的浓度施用 mg / kg体重。 本发明进一步涉及用于治疗和/或预防氧衍生疾病,特别是氧自由基或活性氧衍生疾病的自由基和有害形式的组合物。 本发明进一步涉及作为食物补充剂或膳食补充剂的组合物。

    Optimized oral glucose tolerance test
    7.
    发明授权
    Optimized oral glucose tolerance test 有权
    优化口服葡萄糖耐量试验

    公开(公告)号:US07886697B2

    公开(公告)日:2011-02-15

    申请号:US11951788

    申请日:2007-12-06

    申请人: Haruhiko Inufusa

    发明人: Haruhiko Inufusa

    IPC分类号: A01K1/03

    摘要: Described herein is a method of enhancing the reliability and reproducibility of animal experiments. As described herein, the method relates to an improved oral glucose tolerance test (OGTT) in animals, wherein the set up of the test has been optimized in comparison to the standard procedure for OGTT.

    摘要翻译: 本文描述了增强动物实验的可靠性和再现性的方法。 如本文所述,该方法涉及动物中改进的口服葡萄糖耐量试验(OGTT),其中与OGTT的标准程序相比,测试的建立已被优化。

    USE OF IEX-1 FOR THE TREATMENT OF GLIOMA TUMORS
    8.
    发明申请
    USE OF IEX-1 FOR THE TREATMENT OF GLIOMA TUMORS 审中-公开
    使用IEX-1治疗GLIOMA肿瘤

    公开(公告)号:US20090221675A1

    公开(公告)日:2009-09-03

    申请号:US12162097

    申请日:2007-03-12

    IPC分类号: A61K31/7088

    CPC分类号: C07K14/4747

    摘要: The present invention relates to a nucleic acid molecule encoding for IEX-1 polypeptide as a medicament. In a further aspect the present invention relates to a nucleic acid molecule encoding for IEX-1 polypeptide for the manufacture of a medicament for the treatment of gliomas.

    摘要翻译: 本发明涉及编码IEX-1多肽作为药物的核酸分子。 在另一方面,本发明涉及编码IEX-1多肽的核酸分子,用于制备用于治疗神经胶质瘤的药物。

    COMPOSITION FOR PROTECTION AGAINST CELL-DAMAGING EFFECTS
    9.
    发明申请
    COMPOSITION FOR PROTECTION AGAINST CELL-DAMAGING EFFECTS 有权
    用于保护细胞损伤作用的组合物

    公开(公告)号:US20140314731A1

    公开(公告)日:2014-10-23

    申请号:US14358365

    申请日:2012-11-15

    申请人: TIMA FOUNDATION

    发明人: Haruhiko Inufusa

    摘要: The present invention relates to a composition consisting of Vitamin C, L-glutamine, L-cystine or L-cysteine, riboflavin, succinic acid, fumaric acid, coenzyme Q10, and niacin. The present invention relates further to the use of the composition for minimizing the cell-damaging effect of radicals and harmful forms of oxygen, in particular of oxygen radicals or reactive oxygen species. The present invention relates to a composition comprising Vitamin C, L-glutamine, L-cystine or L-cysteine, riboflavin, succinic acid, fumaric acid, coenzyme Q10, and niacin, wherein the composition is administered in a concentration ranging from 10 to 20 mg/kg body weight. The present invention relates further to the composition for use in the treatment and/or prevention of radical and harmful forms of oxygen derived diseases, in particular of oxygen radical or reactive oxygen species derived diseases. The present invention relates further to the composition as a food supplement or dietary supplement.

    摘要翻译: 本发明涉及由维生素C,L-谷氨酰胺,L-胱氨酸或L-半胱氨酸,核黄素,琥珀酸,富马酸,辅酶Q10和烟酸组成的组合物。 本发明进一步涉及组合物的用途,以最大限度地减少自由基和有害形式的氧,特别是氧自由基或活性氧的细胞破坏作用。 本发明涉及包含维生素C,L-谷氨酰胺,L-胱氨酸或L-半胱氨酸,核黄素,琥珀酸,富马酸,辅酶Q10和烟酸的组合物,其中组合物以10至20的浓度施用 mg / kg体重。 本发明进一步涉及用于治疗和/或预防氧衍生疾病,特别是氧自由基或活性氧衍生疾病的自由基和有害形式的组合物。 本发明进一步涉及作为食物补充剂或膳食补充剂的组合物。