公开(公告)号：US12117307B2

公开(公告)日：2024-10-15

申请号：US17208769

申请日：2021-03-22

申请人： Beijing Didi Infinity Technology and Development Co., Ltd.

发明人： Yan Zhang ,  Tingbo Hou

IPC分类号： G01C21/36 ,  G01S17/89 ,  G06F3/04815

CPC分类号： G01C21/3638 ,  G01C21/3614 ,  G01S17/89 ,  G06F3/04815

摘要： Systems and methods are disclosed related to generating an interactive user interface that enables a user to move, rotate or otherwise edit 3D point cloud data in virtual 3D space to align or match point clouds captured from LiDAR scans prior to generation of a high definition map. A system may obtain point cloud data for two or more point clouds, render the point clouds for display in a user interface, then receive a user selection of one of the point clouds and commands from the user to move and/or rotate the selected point cloud. The system may adjust the displayed position of the selected point cloud relative to the other simultaneously displayed point cloud(s) in real time in response to the user commands, and store the adjusted point cloud position data for use in generating a new high definition map.

公开(公告)号：USD1042817S1

公开(公告)日：2024-09-17

申请号：US29829264

申请日：2022-03-03

申请人： ICU Medical, Inc.

设计人： Thomas F. Fangrow

摘要： FIG. 1 illustrates a front perspective view of a medical connector showing my new design.
FIG. 2 illustrates a rear perspective view thereof; and,
FIG. 3 illustrates a side view thereof, the other side being a mirror image.
The broken lines shown in the figures are included for the purpose of illustrating unclaimed portions of the medical connector and form no part of the claimed design.

公开(公告)号：US12059538B2

公开(公告)日：2024-08-13

申请号：US17161107

申请日：2021-01-28

申请人： Tangent Medical Technologies, Inc.

发明人： Nathan Farrell ,  Adrienne Rose Harris ,  Steven B. White ,  Ronald Dean Duis ,  Henry J. H. Brown

IPC分类号： A61M25/06 ,  A61M5/162 ,  A61M5/32

CPC分类号： A61M25/0631 ,  A61M5/1626 ,  A61M5/3204 ,  A61M5/326 ,  A61M25/0606 ,  A61M25/0618 ,  A61M25/0693

摘要： A safety needle system operable with a medical device includes: a housing with a needle mount having a needle; and a sheath telescopically engaged with the housing and surrounding the needle such that the sheath operates in a retracted position, in which the sheath exposes the needle, and an extended position, in which the sheath surrounds the needle. The sheath is coupleable to the medical device such that removal of the needle from the medical device draws the sheath over the needle, transitioning the sheath from the retracted position to the extended position. The system can include a slider engaged with the sheath and/or housing and including a restraint that engages and disengages the sheath to respectively reinforce and weaken the coupling of the sheath and medical device. The sheath can include a longitudinal track that slidingly engages a setting of the housing between sheath positions.

公开(公告)号：US12054529B2

公开(公告)日：2024-08-06

申请号：US17048928

申请日：2019-04-17

申请人： MEDIZINISCHE HOCHSCHULE HANNOVER ,  HELMHOLTZ ZENTRUM MÜNCHEN—DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH)

发明人： Renata Stripecke ,  Constanze Slabik ,  Reinhard Zeidler ,  Wolfgang Hammerschmidt

IPC分类号： C07K14/725 ,  A61K35/17 ,  A61P31/22 ,  C07K14/705 ,  C07K16/08 ,  A61K39/00

CPC分类号： C07K14/7051 ,  A61K35/17 ,  A61P31/22 ,  C07K14/70517 ,  C07K14/70521 ,  C07K14/70578 ,  C07K16/087 ,  A61K2039/505

摘要： An isolated chimeric antigen receptor (CAR) polypeptide, wherein the CAR includes an extracellular antigen-binding domain, including an antibody or antibody fragment that binds to a protein encoded by a herpes virus, or to a protein complex including the protein (herpes virus antigen), wherein the herpes virus antigen is present on the surface of a human cell that is latently infected with said herpes virus and supports the lytic phase of viral replication. The invention further relates to a nucleic acid molecule encoding the CAR of the invention, a genetically modified immune cell, preferably a T cell, expressing the CAR of the invention and the use of the cell in the treatment of a medical disorder associated with human herpesvirus, such as herpes virus-associated cancers, chronic active herpes virus infections or primary herpes virus infections. In preferred embodiments the herpes virus is Epstein-Barr virus (EBV) and a preferred herpes virus antigen target of the CAR is the EBV glycoprotein 350/220 (gp350/gp220).

公开(公告)号：US11896415B2

公开(公告)日：2024-02-13

申请号：US17654883

申请日：2022-03-15

申请人： CLEERLY, INC.

发明人： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques

IPC分类号： A61B6/00 ,  G06T7/00 ,  A61B5/055 ,  A61B6/03 ,  A61B8/14 ,  A61B8/12 ,  A61B5/00 ,  A61K49/04 ,  G06F18/10 ,  G06V10/74 ,  G06V10/764 ,  G06V10/82 ,  G06V10/20 ,  G06V10/24

CPC分类号： A61B6/504 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/055 ,  A61B5/7267 ,  A61B5/742 ,  A61B5/7475 ,  A61B6/032 ,  A61B6/037 ,  A61B6/463 ,  A61B6/467 ,  A61B6/481 ,  A61B6/5205 ,  A61B8/12 ,  A61B8/14 ,  A61K49/04 ,  G06F18/10 ,  G06T7/0012 ,  G06V10/20 ,  G06V10/245 ,  G06V10/761 ,  G06V10/764 ,  G06V10/82 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06V10/247

摘要： The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US11884469B2

公开(公告)日：2024-01-30

申请号：US16595216

申请日：2019-10-07

申请人： Fisher & Paykel Healthcare Limited

发明人： Jeroen Hammer ,  Mark Arvind McLaren ,  Abby Rebecca Farrow ,  Jonathan Neil Ritchie

IPC分类号： A61M16/06 ,  B65D73/00 ,  B65D75/00 ,  B65D77/04 ,  B65D65/46 ,  B65D85/18 ,  B65D25/10

CPC分类号： B65D73/0085 ,  A61M16/0683 ,  B65D25/10 ,  B65D65/466 ,  B65D75/008 ,  B65D77/04 ,  B65D85/18 ,  A61M2209/06 ,  B65D2203/02

摘要： A packaging system for a respiratory mask has a first compartment configured to receive at least a first portion of the respiratory mask, and a second compartment configured to receive at least a second portion of the respiratory mask, the first and second compartments being separated by an internal wall including at least respiratory mask retention feature that may be configured to retain at least the respiratory mask to the packaging system.

公开(公告)号：US11834045B2

公开(公告)日：2023-12-05

申请号：US17061438

申请日：2020-10-01

申请人： MOTIONAL AD LLC

发明人： Scott Drew Pendleton

IPC分类号： B60W30/18 ,  B60W60/00

CPC分类号： B60W30/18159 ,  B60W30/18154 ,  B60W60/00272 ,  B60W2552/53 ,  B60W2554/4044 ,  B60W2555/60 ,  B60W2720/106

摘要： The subject matter described in this specification is directed to a system and techniques for operating an autonomous vehicle (AV) at a multi-way stop intersection. After detecting the AV is at a primary stopline of the multi-way stop intersection, a planned travel path though the multi-way stop intersection is obtained. If the planned travel path of the AV through the multi-way stop intersection satisfies a set of one or more clearance criteria, the AV proceeds past the primary stopline. The clearance criteria include a criterion that is satisfied in response to detecting the AV is clear to safely merge into a travel lane corresponding to the planned travel path.

公开(公告)号：US11766229B2

公开(公告)日：2023-09-26

申请号：US18148697

申请日：2022-12-30

申请人： CLEERLY, INC.

发明人： James K. Min ,  James P. Earls ,  Hugo Miguel Rodrigues Marques

IPC分类号： A61B6/00 ,  G06T7/00 ,  A61B5/055 ,  A61B6/03 ,  A61B8/14 ,  A61B8/12 ,  A61B5/00 ,  A61K49/04 ,  G06F18/10 ,  G06V10/74 ,  G06V10/764 ,  G06V10/82 ,  G06V10/20 ,  G06V10/24

CPC分类号： A61B6/504 ,  A61B5/0066 ,  A61B5/0075 ,  A61B5/055 ,  A61B5/7267 ,  A61B5/742 ,  A61B5/7475 ,  A61B6/032 ,  A61B6/037 ,  A61B6/463 ,  A61B6/467 ,  A61B6/481 ,  A61B6/5205 ,  A61B8/12 ,  A61B8/14 ,  A61K49/04 ,  G06F18/10 ,  G06T7/0012 ,  G06V10/20 ,  G06V10/245 ,  G06V10/761 ,  G06V10/764 ,  G06V10/82 ,  G06T2207/10081 ,  G06T2207/10088 ,  G06T2207/10101 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30048 ,  G06T2207/30101 ,  G06V10/247

摘要： The disclosure herein relates to systems, methods, and devices for medical image analysis, diagnosis, risk stratification, decision making and/or disease tracking. In some embodiments, the systems, devices, and methods described herein are configured to analyze non-invasive medical images of a subject to automatically and/or dynamically identify one or more features, such as plaque and vessels, and/or derive one or more quantified plaque parameters, such as radiodensity, radiodensity composition, volume, radiodensity heterogeneity, geometry, location, and/or the like. In some embodiments, the systems, devices, and methods described herein are further configured to generate one or more assessments of plaque-based diseases from raw medical images using one or more of the identified features and/or quantified parameters.

公开(公告)号：US11759161B2

公开(公告)日：2023-09-19

申请号：US17662762

申请日：2022-05-10

申请人： Cleerly, Inc.

发明人： James K. Min

IPC分类号： A61B6/00 ,  A61B6/03 ,  G06T7/00

CPC分类号： A61B6/504 ,  A61B6/032 ,  A61B6/5217 ,  A61B6/5223 ,  G06T7/0012 ,  G06T7/97 ,  G06T2207/10028 ,  G06T2207/10072 ,  G06T2207/30101

摘要： A method for characterization of coronary plaque tissue data and perivascular tissue data using image data gathered from a computed tomography (CT) scan along a blood vessel, the image information including radiodensity values of coronary plaque and perivascular tissue located adjacent to the coronary plaque, the method comprising quantifying radiodensity in regions of coronary plaque, quantifying, radiodensity in at least one region of corresponding perivascular tissue adjacent to the coronary plaque, determining gradients of the quantified radiodensity values within the coronary plaque and the quantified radiodensity values within the corresponding perivascular tissue, and determining a ratio of the quantified radiodensity values within the coronary plaque and the corresponding perivascular tissue; and characterizing the coronary plaque by analyzing a gradient of the quantified radiodensity values in the coronary plaque and the corresponding perivascular, and/or the ratio of the coronary plaque radiodensity values and the radiodensity values of the corresponding perivascular tissue.

公开(公告)号：US11758695B2

公开(公告)日：2023-09-12

申请号：US17456288

申请日：2021-11-23

申请人： Digital Porpoise, LLC

发明人： Steven William Dumas ,  Jason Wilfred Clark ,  Michael Streich

IPC分类号： G06F1/16 ,  H05K5/00 ,  H05K7/00 ,  H05K7/20

CPC分类号： H05K7/208 ,  H05K7/20145 ,  H05K7/20172 ,  H05K7/20327 ,  H05K7/20718

摘要： A data center cooling system, including a support structure having a lower portion and an upper portion, one or more fans supported by the support structure at a height that is equal to or greater than a height of the electronics cabinets, and a heat exchanger having one or more cooling coils supported at the upper portion of the support structure. In some embodiments, the cooling coils can be supported by the upper portion of the support structure so as to be above the top of and/or over one or more of the electronics cabinets. The fans can be configured to draw air from the one or two rows of electronics cabinets and to cause the air to be passed through the heat exchanger to cool the warmer air from the electronics cabinets.