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公开(公告)号:US10568943B2
公开(公告)日:2020-02-25
申请号:US16271686
申请日:2019-02-08
发明人: Glenn Pierce , Samantha Truex , Robert T. Peters , Haiyan Jiang
IPC分类号: A61K38/36 , A61K38/48 , A61K47/64 , A61K39/395 , C12N9/96 , A61K38/38 , C07K16/18 , C12N9/64 , C07K14/76 , A61K9/00 , A61P7/04
摘要: The present invention provides methods of administering Factor IX; methods of administering chimeric and hybrid polypeptides comprising Factor IX; polynucleotides encoding such chimeric and hybrid polypeptides; cells comprising such polynucleotides; and methods of producing such chimeric and hybrid polypeptides using such cells.
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公开(公告)号:US10566827B2
公开(公告)日:2020-02-18
申请号:US15561880
申请日:2017-01-07
发明人: Chen Tian , Jialiang Zhang
IPC分类号: H02J7/00 , H02J7/02 , G01R31/3842 , H02M3/335 , H02J7/04 , H02M7/217 , H02J7/06 , H02M1/08 , H02M7/06 , H01M10/0525 , H01M10/42 , H01M10/44 , H02M1/44 , H02M5/04 , H02M7/04 , H02M1/00 , H02J7/10
摘要: Disclosed are an adapter and a charging control method. The adapter includes a power conversion unit, a sampling and holding unit, and a current collecting and controlling unit. The power conversion unit is configured to convert input alternating current to obtain output voltage and output current, in which the output current is first current with first pulsating waveform. The sampling and holding unit is configured to sample the first current when the sampling and holding unit is in a sampling state, and to hold a peak value of the first current when the sampling and holding unit is in a holding state. The current collecting and controlling unit is configured to determine whether the sampling and holding unit is in the holding state, and to collect the peak value of the first current when the sampling and holding unit is in the holding state.
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公开(公告)号:USD874552S1
公开(公告)日:2020-02-04
申请号:US29700582
申请日:2019-08-02
设计人: Christopher Loew , James Siminoff , Spiro Sacre , Mark Siminoff
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公开(公告)号:USD874551S1
公开(公告)日:2020-02-04
申请号:US29700577
申请日:2019-08-02
设计人: Christopher Loew , James Siminoff , Spiro Sacre , Mark Siminoff
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公开(公告)号:US10552967B2
公开(公告)日:2020-02-04
申请号:US15907003
申请日:2018-02-27
申请人: Isolynx, LLC
摘要: A method for using tracking tags to control mobile cameras to determine and capture desired perspective views of objects of interest (OOIs), includes locating each OOI and determining an orientation of each OOI. A second location of each mobile camera is determined with an orientation of each mobile camera; the method includes controlling, based upon the first and second location, and the orientations, the mobile camera to maintain desired perspective views of the OOIs despite movement of the OOIs. The method executes on a system for controlling a mobile camera including tracking tags configured with each OOI and tracking tags configured with the mobile cameras. A tracking apparatus having at least three receivers positioned around an operational area receives locate signals from the tracking tags to determining location data and a processor determines movement plans for the mobile cameras.
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公开(公告)号:US10547618B2
公开(公告)日:2020-01-28
申请号:US15724779
申请日:2017-10-04
发明人: Miao Zhang , Xin Li , Guang Yao , Jiyang Zhang , Heyi Tang , Gongwei Wu
摘要: Disclosed are a method and an apparatus for setting an access privilege. The method includes: acquiring Internet Protocol (IP) addresses having a access frequency to a target application greater than or equal to a frequency threshold, selecting IP addresses accessing more than one applications per time unit from the IP addresses as to-be-processed IP addresses to generate a to-be-processed IP address set; acquiring access information, related to an access of a target application, of the to-be-processed IP address; acquiring a plurality of target IP addresses in the to-be-processed IP address set based on the access information, determining a probability of access through a gateway by a terminal pointed by each target IP address; and selecting a preset proportion or a preset number of target IP addresses from the plurality of target IP addresses in a descending order of the probability to set the access privilege.
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公开(公告)号:US10546369B2
公开(公告)日:2020-01-28
申请号:US15865880
申请日:2018-01-09
发明人: Fanbo Deng , Chengming Liu , Sarvesh Swami
摘要: A method for determining exposure levels of an image-sensor pixel array includes (a) storing a first plurality of pixel values representing a first captured image, captured with the image sensor in an applied exposure configuration, each distinct region of the pixel array having a respective first exposure level, (b) determining pixel-value global statistics, (c) estimating, from the global statistics, a global pixel value of the first captured image, (d) determining, for each distinct region, a respective local statistics of the first pixel values, (e) assigning, to each distinct region, a respective scale factor based on the local statistics of the distinct region, (f) determining a refined exposure configuration including, for each distinct region, a second exposure level proportional to a product of its respective first exposure level and its respective scale factor, and (g) capturing second pixel values with the image sensor configured in the refined exposure configuration.
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公开(公告)号:US10544232B2
公开(公告)日:2020-01-28
申请号:US14801384
申请日:2015-07-16
发明人: Marie Baccara-Dinet , Corinne Hanotin , Laurence Bessac , Umesh Chaudhari , Robert C. Pordy , William J. Sasiela , Daniel A. Schwemmer Gipe
IPC分类号: A61K39/395 , A61P3/06 , C07K16/40 , C07K14/705 , A61K39/00
摘要: The present invention provides methods for treating hypercholesterolemia. The methods of the present invention comprise administering to patients with heterozygous familial hypercholesterolemia a pharmaceutical composition comprising a PCSK9 inhibitor. In certain embodiments, the PCSK9 inhibitor is an anti-PCSK9 antibody such as the exemplary antibody referred to herein as mAb316P. The methods of the present invention are useful for treating patients with heterozygous familial hypercholesterolemia who are not adequately controlled by maximum tolerated dose statin therapy with or without other lipid lowering therapy.
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公开(公告)号:US10544141B2
公开(公告)日:2020-01-28
申请号:US16118760
申请日:2018-08-31
发明人: George D. Hartman , Scott Kuduk
IPC分类号: C07D471/04 , A61K38/21 , A61K39/29 , C12N7/00 , A61K31/437 , A61K31/5377 , A61K45/06 , A61K31/4545 , A61P31/12 , A61K31/501
摘要: Provided herein are compounds useful for the treatment of HBV infection in a subject in need thereof, pharmaceutical compositions thereof, and methods of inhibiting, suppressing, or preventing HBV infection in the subject.
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公开(公告)号:US10542814B2
公开(公告)日:2020-01-28
申请号:US16060457
申请日:2016-12-10
申请人: AIROSOLUTIONS NV
发明人: Quint Kelders , Mark Brouwer , Mervin Cleij
摘要: A new lip balm applicator comprises an upper portion and a lower portion that are interengageably connected to one another to define the applicator, and a support assembly for supporting a solidified lip balm material within the applicator. The support assembly comprises supporting ribs formed on an inner surface of the lower portion and a lower opening having a closing lid, whereby the solidified lip balm material circumvents at least part of the supporting ribs. A novel method for manufacturing the lip balm applicator comprises interengaging the upper and lower portions of the lip balm applicator and pouring a liquefied lip balm material into the lower opening until at least part of the projecting supporting ribs are covered by the liquefied balm material and solidified.
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