公开(公告)号：US12127863B2

公开(公告)日：2024-10-29

申请号：US17308337

申请日：2021-05-05

申请人： WARSAW ORTHOPEDIC INC.

发明人： Roger P. Jackson

IPC分类号： A61G13/02 ,  A61B6/04 ,  A61G7/00 ,  A61G7/008 ,  A61G13/00 ,  A61G13/04 ,  A61G13/06 ,  A61G13/08 ,  A61G13/10

CPC分类号： A61B6/0407 ,  A61G7/001 ,  A61G7/008 ,  A61G13/0036 ,  A61G13/0054 ,  A61G13/02 ,  A61G13/04 ,  A61G13/06 ,  A61G13/08 ,  A61G13/104 ,  A61G2200/325

摘要： A patient support system includes independently adjustable end columns supporting a centrally hinged, jointed or breaking patient support structure. At least one column includes a powered rotation assembly. The patient support includes at least two sections. A coordinated drive system provides for both upwardly and downwardly breaking or jointed orientations of the two sections in various inclined and tilted positions. Cable, cantilevered and pull-rod systems are included.

公开(公告)号：US12114845B2

公开(公告)日：2024-10-15

申请号：US17606010

申请日：2019-04-23

申请人： Warsaw Orthopedic, Inc.

发明人： Loic Josse ,  Bertrand Peultier

IPC分类号： A61B17/02 ,  A61B17/70 ,  A61B90/00

CPC分类号： A61B17/0206 ,  A61B17/025 ,  A61B17/708 ,  A61B17/7085 ,  A61B2017/0256 ,  A61B2090/061

摘要： A surgical system includes an implant support engageable, in operation of the system, with a receiver of a bone fastener having a shaft fixed with vertebral tissue. The receiver being connectable to at least one extender tab. The implant support including a connector being releasably engageable with the at least one extender tab. The implant support further including an adaptor. At least a portion of the adaptor being movable relative to the connector to releasably engage a surgical instrument to distract and/or compress the vertebral tissue. Surgical instruments, constructs, implants and methods are disclosed.

公开(公告)号：US12076105B2

公开(公告)日：2024-09-03

申请号：US17308319

申请日：2021-05-05

申请人： WARSAW ORTHOPEDIC INC.

发明人： Thomas V. McGahan ,  Roy K. Lim

IPC分类号： A61B46/00 ,  A61B46/20 ,  A61B46/27 ,  A61B17/00

CPC分类号： A61B46/27 ,  A61B46/00 ,  A61B46/20 ,  A61B46/40 ,  A61B2017/00946 ,  A61B2046/205

摘要： A surgical drape includes a seal connectable with a selected surface of a body to define a sterile region that includes access to at least two surgical approaches. A sleeve is connected with the seal and a draping is disposed with the body. The sleeve defines a cavity in communication with the region. Surgical instruments, systems and methods are disclosed.

公开(公告)号：US12064157B2

公开(公告)日：2024-08-20

申请号：US17217510

申请日：2021-03-30

申请人： MEDTRONIC HOLDING COMPANY SÀRL

发明人： Hester Chan ,  Amy L. Arthur ,  Trevor T. Seck

IPC分类号： A61B17/88 ,  A61B17/34

CPC分类号： A61B17/8811 ,  A61B17/3421 ,  A61B17/3472 ,  A61B17/8855 ,  A61B2017/3454

摘要： A method of treating a bone of a patient includes identifying a portion of the patient to be protected. A cannula is provided that includes a shaft extending between opposite first and second end surfaces. The shaft incudes an inner surface defining a lumen. The cannula includes a scoop extending from the second end surface. The scoop includes an inner surface that is continuous with the inner surface of the shaft and an opposite outer surface. The cannula is inserted into the bone such that the outer surface of the scoop is positioned adjacent to the portion of the patient to be protected. A balloon is inserted into the cannula such that the balloon is positioned within the scoop. The balloon is inflated such that the balloon expands away from the scoop as the balloon is inflated and creates a void in the bone. Systems are disclosed.

公开(公告)号：US12064143B2

公开(公告)日：2024-08-20

申请号：US17975725

申请日：2022-10-28

申请人： Warsaw Orthopedic, Inc.

发明人： Keith E. Miller

IPC分类号： A61B17/70 ,  A61B17/00

CPC分类号： A61B17/7019 ,  A61B17/7011 ,  A61B2017/00407

摘要： A spinal implant includes a first member having an arcuate portion and a second member having an arcuate portion. The first member is connected with a first portion of vertebrae and the second member is connected with a second portion of vertebrae such that the second portion of vertebrae is disposed at a first angle relative to the first portion of vertebrae in a sagittal plane of the vertebrae. A ratchet is disposed with the members such that the first member is incrementally movable relative to the second member from the first angle to a selected angle of the second portion relative to the first portion in the sagittal plane. Systems, implants and methods are disclosed.

公开(公告)号：US12060591B2

公开(公告)日：2024-08-13

申请号：US16822906

申请日：2020-03-18

申请人： Oligomerix, Inc.

发明人： James G. Moe ,  Eliot J. Davidowitz ,  Patricia Lopez

IPC分类号： C12N9/64 ,  A61K38/00 ,  A61K38/48 ,  A61K39/395 ,  C07K16/40 ,  C12Q1/37 ,  G01N33/573 ,  G01N33/68

CPC分类号： C12N9/6424 ,  A61K38/482 ,  A61K39/3955 ,  C07K16/40 ,  C12Q1/37 ,  G01N33/573 ,  G01N33/6896 ,  A61K38/00 ,  G01N2800/2821

摘要： Disclosed are mammalian tau proteases, as well as proteolytically-active fragments, variants, and mutants thereof. Also disclosed are polynucleotides and recombinant expression vectors that encode these polypeptides, as well as methods for producing such proteins in selected recombinant host cells, and for using the compositions in a variety of diagnostic and analytical assays.

公开(公告)号：US12060194B2

公开(公告)日：2024-08-13

申请号：US18190248

申请日：2023-03-27

申请人： RING CONTAINER TECHNOLOGIES, LLC

发明人： Douglas Miles Dygert ,  Douglas Alan Woodring

IPC分类号： B65D1/02 ,  B29C49/06 ,  B65D41/06 ,  B29K67/00

CPC分类号： B65D1/0246 ,  B29C49/06 ,  B65D1/0276 ,  B65D41/06 ,  B29K2067/003 ,  B65D2501/0036

摘要： A plastic, hot-fillable container is provided. The container comprises a blow molded body defining a longitudinal axis. The body including a base and a neck having at least one rib disposed about at least a portion of a circumference of the neck and transverse to the axis, and at least one angled thread. The at least one rib defining a cross section having a first portion and a second angled portion. Container systems and methods of manufacturing containers are provided.

公开(公告)号：US12023468B2

公开(公告)日：2024-07-02

申请号：US16980253

申请日：2019-03-12

申请人： MYLAN UK HEALTHCARE LTD. ,  COALESCE PRODUCT DEVELOPMENT LIMITED

发明人： Michael John Holroyd ,  Robin Craig Cocker ,  James Terrence Collins ,  Paul Christopher Edward Mutti ,  Daniel Colin Jackson ,  Michael Edgar Newton

IPC分类号： A61M5/20 ,  A61M5/315 ,  A61M5/32 ,  A61M5/24

CPC分类号： A61M5/20 ,  A61M5/2033 ,  A61M5/31591 ,  A61M5/3202 ,  A61M5/3204 ,  A61M5/326 ,  A61M2005/2013 ,  A61M2005/2403 ,  A61M2005/2488 ,  A61M2005/3267

摘要： A device for injecting a medicament is provided. The device has a housing with a container within it which can hold a medicament. At its proximal end the container has a needle and a stopper. The device includes a plunger which at one end can engage the stopper. At the opposite end, the plunger can engage a first resilient member to move the stopper within the container to inject the medicament from the container. The device includes a collar with distal and proximal ends, the distal end engaging with a carriage and causing its rotation and the proximal end engaging with a second resilient member. The second resilient member can engage with a skin sensor which has distal and proximal ends. At the proximal end, the skin sensor can contact an injection site. The housing has a cap which can reduce or prevent movement of the skin sensor.

公开(公告)号：US12011358B2

公开(公告)日：2024-06-18

申请号：US17185046

申请日：2021-02-25

申请人： WARSAW ORTHOPEDIC INC.

发明人： Jeffrey W. Beale ,  Keith E. Miller ,  William Alan Rezach ,  Richard A. Hynes

IPC分类号： A61F2/44 ,  A61B17/70 ,  A61F2/46 ,  A61F2/30

CPC分类号： A61F2/44 ,  A61B17/70 ,  A61B17/7077 ,  A61F2/442 ,  A61F2/4455 ,  A61F2/4611 ,  A61F2002/30171 ,  A61F2002/30224 ,  A61F2002/30232 ,  A61F2002/30235 ,  A61F2002/30242 ,  A61F2002/30299 ,  A61F2002/305 ,  A61F2002/30538 ,  A61F2002/30556 ,  A61F2002/30563 ,  A61F2002/30607 ,  A61F2002/30616 ,  A61F2002/30841 ,  A61F2002/30904 ,  A61F2002/443 ,  A61F2002/4693 ,  A61F2002/4694

摘要： A method for treating a spine includes the steps of: creating a surgical pathway in a body along a first surgical approach to a surgical site including vertebral tissue; creating a surgical pathway in the body along a second surgical approach to the surgical site including the vertebral tissue; disposing a fulcrum with an intervertebral disc space of the vertebral tissue via the first surgical approach; and manipulating the vertebral tissue via the second surgical approach. Spinal implants, surgical instruments and systems are disclosed.

公开(公告)号：US12005160B2

公开(公告)日：2024-06-11

申请号：US16996245

申请日：2020-08-18

申请人： WARSAW ORTHOPEDIC INC.

发明人： Anthony J. Melkent ,  Brian R. Thoren ,  Timothy J. N. Smith ,  Ian D. Grant ,  Ian R. Dunkley

IPC分类号： A61L31/12 ,  A61F2/44 ,  A61L27/42 ,  A61L27/56 ,  A61L27/58 ,  B05D1/18 ,  B05D3/02 ,  B29C45/00 ,  B29C45/14 ,  C04B38/00 ,  C04B41/45 ,  C04B41/81 ,  C08L71/12 ,  A61F2/30 ,  A61L27/46 ,  B29K71/00 ,  B29L31/00

CPC分类号： A61L31/121 ,  A61F2/4455 ,  A61L27/425 ,  A61L27/56 ,  A61L27/58 ,  B05D1/18 ,  B05D3/0272 ,  B29C45/0055 ,  B29C45/14795 ,  C04B38/0051 ,  C04B41/4586 ,  C04B41/81 ,  C08L71/12 ,  A61F2002/30028 ,  A61F2002/30032 ,  A61F2002/30062 ,  A61F2002/30187 ,  A61F2002/30593 ,  A61F2/30724 ,  A61F2002/30957 ,  A61F2002/30973 ,  A61L27/46 ,  A61L2400/08 ,  A61L2400/18 ,  A61L2420/02 ,  A61L2420/04 ,  B29C2045/0058 ,  B29K2071/00 ,  B29L2031/7532 ,  C04B2235/606 ,  A61L27/425 ,  C08L71/12

摘要： Implantable medical devices are provided. In one embodiment, a device includes a body having an external surface defining an outer profile of the device. The body includes a porous matrix including a series of interconnected macropores defined by a plurality of interconnected struts each including a hollow interior. A filler material substantially fills at least a portion of the series of interconnected macropores. The external surface of the body includes a plurality of openings communicating with the hollow interior of at least a portion of the plurality of interconnected struts. In a further aspect of this embodiment, the external surface includes exposed areas of the filler material and porous matrix in addition to the exposed openings. In another aspect, the porous matrix is formed from a bioresorbable ceramic and the filler material is a biologically stable polymeric material. Still, other aspects related to this and other embodiments are also disclosed.