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公开(公告)号:US08685439B2
公开(公告)日:2014-04-01
申请号:US11796278
申请日:2007-04-26
IPC分类号: A61F13/02
CPC分类号: A61K31/40 , A61K9/0048 , A61K31/045 , A61K31/047 , A61K31/137 , A61K31/70 , A61K31/7016 , A61K33/14
摘要: The invention features novel topical ophthalmic formulations comprising an osmotically active agent and a vasoconstrictor. Suitable osmotically active agents for use in the ophthalmic formulations of the invention include, without limitation, sodium chloride, dextrose, glycerine, sucrose, mannitol, and sorbitol; suitable vasoconstritors include, without limitation, naphazoline and oxymetazoline. Also provided are methods of using the ophthalmic formulations of the invention for the treatment and prevention of eyelid swelling by administering the ophthalmic formulations of the invention to the eye surface of a subject in need thereof.
摘要翻译: 本发明的特征在于包含渗透活性剂和血管收缩剂的新型局部眼用制剂。 用于本发明的眼用制剂的合适的渗透活性剂包括但不限于氯化钠,葡萄糖,甘油,蔗糖,甘露糖醇和山梨糖醇; 合适的血管收缩剂包括但不限于萘并唑啉和羟甲唑啉。 还提供了使用本发明的眼用制剂用于治疗和预防眼睑肿胀的方法,其通过将本发明的眼用制剂施用于有需要的受试者的眼表。
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2.
公开(公告)号:US20120021072A1
公开(公告)日:2012-01-26
申请号:US13238891
申请日:2011-09-21
IPC分类号: A61K33/14 , A61K31/715 , A61P27/02 , A61K31/135 , A61K31/047 , A61K38/38 , A61K31/4164
CPC分类号: A61K31/40 , A61K9/0048 , A61K31/045 , A61K31/047 , A61K31/137 , A61K31/70 , A61K31/7016 , A61K33/14
摘要: The invention features topical formulations comprising an osmotically active agent and/or a vasoconstrictor and/or an astringent agent for the treatment and prevention of eyelid swelling, and methods of use thereof.
摘要翻译: 本发明的特征在于包含用于治疗和预防眼睑肿胀的渗透活性剂和/或血管收缩剂和/或收敛剂的局部制剂及其使用方法。
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公开(公告)号:US20070264318A1
公开(公告)日:2007-11-15
申请号:US11796278
申请日:2007-04-26
申请人: Matthew Chapin , Mark Abelson , Keith Lane , Akimitsu Makino
发明人: Matthew Chapin , Mark Abelson , Keith Lane , Akimitsu Makino
IPC分类号: A61K31/70 , A61K31/045 , A61K33/14
CPC分类号: A61K31/40 , A61K9/0048 , A61K31/045 , A61K31/047 , A61K31/137 , A61K31/70 , A61K31/7016 , A61K33/14
摘要: The invention features topical formulations comprising an osmotically active agent and/or a vasoconstrictor and/or an astringent agent for the treatment and prevention of eyelid swelling, and methods of use thereof.
摘要翻译: 本发明的特征在于包含用于治疗和预防眼睑肿胀的渗透活性剂和/或血管收缩剂和/或收敛剂的局部制剂及其使用方法。
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