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    IL-12 production inhibitor
    2.
    发明授权
    IL-12 production inhibitor 有权
    IL-12生产抑制剂

    公开(公告)号：US06436911B1

    公开(公告)日：2002-08-20

    申请号：US09620747

    申请日：2000-07-21

    申请人： Akira Asari ,  Hitoshi Kurihara ,  Heping Xu ,  Satoshi Miyauchi ,  Toshikazu Minamisawa

    发明人： Akira Asari ,  Hitoshi Kurihara ,  Heping Xu ,  Satoshi Miyauchi ,  Toshikazu Minamisawa

    IPC分类号： A01N4304

    CPC分类号： A61K31/7024

    摘要： An IL-12 production inhibitor which comprises, as an active ingredient, a keratan sulfate oligosaccharide or a derivative thereof, for example, a keratan sulfate oligosaccharide comprising at least one repeating unit of either one of the disaccharides represented by the following formulas: Gal (6s)-GlcNAc (6s) and Gal (6s)-GlcNAc wherein Gal represents a galactose residue, GlcNAc represents an N-acetylglucosamine residue, 6s indicates that 6-0-sulfate ester is formed at a Hydroxyl group at the 6-position, and - represents a glycosidic linkage.

    摘要翻译： 作为活性成分的含有硫酸角质素寡糖或其衍生物的IL-12产生抑制剂，例如硫酸角质素寡糖，其包含由下式表示的二糖中的至少一个重复单元：Gal（ 6s）-GlcNAc（6s）和Gal（6s）-GlcNAc，其中Gal表示半乳糖残基，GlcNAc表示N-乙酰葡糖胺残基，6s表示6位羟基上形成6-0-硫酸酯， 和 - 表示糖苷键。

    Method and apparatus for ejecting jammed billets from metal extrusion press
    4.
    发明授权
    Method and apparatus for ejecting jammed billets from metal extrusion press 失效
    从金属挤压机中排出卡塞坯料的方法和装置

    公开(公告)号：US4777814A

    公开(公告)日：1988-10-18

    申请号：US285287

    申请日：1981-07-20

    申请人： Akira Asari ,  Tsuneharu Masuda

    发明人： Akira Asari ,  Tsuneharu Masuda

    IPC分类号： B21C23/21 ,  B21C35/00 ,  B21C35/04 ,  B21C35/06

    CPC分类号： B21C35/06 ,  B21C23/218 ,  B21C35/00

    摘要： Method and apparatus for removing a jammed billet from a container on a metal extrusion press in which a billet in a container is extruded through a die at the fore end of a die stem by relative movement of the die stem admitted into the container while the billet and container are held stationary relative to each other. Should the billet in the container jam, pressure is applied on the rear end face of the billet in the axial pressing direction thereby extruding the billet in the counter-pressing axial direction.

    摘要翻译： 用于从金属挤压机上的容器中取出卡住的坯料的方法和装置，其中通过容纳在容器中的模头的相对运动将容器中的坯料挤出通过模头前端的模具，同时坯料 并且容器相对于彼此保持静止。 如果容器中的坯料堵塞，则沿着轴向按压方向对坯料的后端面施加压力，从而沿反向挤压轴向挤压坯料。

    Multiple-container type cold isostatic press
    5.
    发明授权
    Multiple-container type cold isostatic press 失效
    多容器式冷等静压机

    公开(公告)号：US4755119A

    公开(公告)日：1988-07-05

    申请号：US29999

    申请日：1987-03-26

    申请人： Akira Asari ,  Yoshikazu Kishi

    发明人： Akira Asari ,  Yoshikazu Kishi

    IPC分类号： B30B11/00 ,  B29C3/00

    CPC分类号： B30B11/001 ,  Y10S425/201

    摘要： A cold isostatic press of the multiple container type including a press frame and an upper plug movable toward and away from a plurality of shaping containers and adapted to perform an operation of loading or unloading a first shaping material from a container and a pressure-forming operation on a second container concurrently at different positions, characterized in that the cold isostatic press includes a plurality of stationary shaping containers securely mounted on a fixed container frame. The press frame is supported linearly reciprocably or swingably for movement to and from a plurality of containers on the fixed container frame.

    摘要翻译： 一种多容器式的冷等静压机，包括一个能够朝向和远离多个成形容器移动的按压框架和上部塞子，并且适于执行从容器装载或卸载第一成形材料的操作和压力成形操作 在第二容器上同时处于不同位置，其特征在于，所述冷等静压机包括牢固地安装在固定容器框架上的多个固定成型容器。 压框被线性地往复运动或可摆动地支撑以移动到固定容器框架上的多个容器。

    Ultra-high pressure solid pressing machine
    6.
    发明授权
    Ultra-high pressure solid pressing machine 失效
    超高压固压机

    公开(公告)号：US4740147A

    公开(公告)日：1988-04-26

    申请号：US839032

    申请日：1986-03-12

    申请人： Akira Asari ,  Shiro Sakamoto

    发明人： Akira Asari ,  Shiro Sakamoto

    IPC分类号： B01J3/06 ,  B30B7/02 ,  B30B11/00 ,  B29C33/02

    CPC分类号： B30B11/007 ,  B01J3/065 ,  B30B11/004 ,  B30B7/02 ,  Y10S425/013

    摘要： An ultra-high pressure solid pressing machine of the type having a pair of upper and lower platens mounted in a press frame and movable relatively toward and away from each other, a mold unit interposed between the upper and lower platens and including at least a cylindrical cavity for receiving raw material therein, upper and lower conical surfaces formed around the upper and lower ends of the cylindrical cavity, and upper and lower anvils fitted respectively in the upper and lower conical surfaces through a gasket to compress the raw material in the cylindrical cavity under an ultra-high pressure, characterized in that the pressing machine includes a plurality of mold units stacked one on another between the upper and lower platens through insulators with axes of cylindrical cavities of the respective mold units being in vertical alignment with each other and a current supply control separately connected to the mold units.

    摘要翻译： 一种超高压固体压制机，其具有安装在压机框架中并相对于彼此相对移动的一对上压板和下压板;插入在上压板和下压板之间的模具单元，并且至少包括圆柱形 用于在其中容纳原料的空腔，围绕圆柱形腔的上端和下端形成的上和下锥形表面，以及分别通过垫圈装配在上锥形表面和下圆锥形表面中的上砧和下砧，以压缩圆柱形腔中的原材料 在超高压下，其特征在于，所述压制机包括通过绝缘体在所述上压板和下压板之间彼此堆叠的多个模具单元，所述模具单元的圆柱形腔的轴线彼此垂直对准，并且 电源供应控制单独连接到模具单元。

    Hot isostatic press apparatus
    7.
    发明授权
    Hot isostatic press apparatus 失效
    热等静压机

    公开(公告)号：US4720256A

    公开(公告)日：1988-01-19

    申请号：US751593

    申请日：1985-07-03

    申请人： Akira Asari ,  Tsuneharu Masuda ,  Masanori Kurita ,  Tsuneya Ueno

    发明人： Akira Asari ,  Tsuneharu Masuda ,  Masanori Kurita ,  Tsuneya Ueno

    IPC分类号： B22F3/03 ,  B22F3/15 ,  B30B11/00 ,  B30B9/28

    CPC分类号： B30B11/002 ,  B22F3/03 ,  B22F3/15

    摘要： A hot isostatic press apparatus wherein a material to be processed such as preliminarily shaped metal powder is charged into a high pressure vessel provided with a heater and the material to be processed is pressed by superhigh pressure of fluid or gas sealed into the vessel and heating by a heater. The apparatus includes a main station including a high pressure vessel, a movable cover, a member for moving the material to be processed; one or more auxiliary stations including an inserting station, a preheating station, a removing station, etc.; a sealed tank; and transfer mechanisms for the material to be processed. The apparatus also includes a seal leakage detector.

    摘要翻译： 一种热等静压机，其中将预先形成的金属粉末的待处理材料装入设置有加热器的高压容器中，并且通过超高压流体或气体将被处理材料压入容器中并通过 一个加热器。 该装置包括主站，包括高压容器，可移动盖，用于移动待处理材料的构件; 一个或多个辅助站，包括插入站，预热站，移除站等; 密封罐; 以及待处理材料的转移机制。 该装置还包括密封泄漏检测器。

    High pressure apparatus
    8.
    发明授权
    High pressure apparatus 失效
    高压设备

    公开(公告)号：US4582212A

    公开(公告)日：1986-04-15

    申请号：US578081

    申请日：1984-02-08

    申请人： Akira Asari

    发明人： Akira Asari

    IPC分类号： F16J12/00 ,  B01J3/04 ,  B01J3/06 ,  B65D25/20

    CPC分类号： B30B15/042 ,  B01J3/048 ,  B01J3/06 ,  B30B11/002

    摘要： A high pressure apparatus including a container internally provided with a cylindrical space capable of being closed, which container is constituted by a unitary member or an integral assembly of a plurality of members joined throughout its full axial length; a cotter member or a pin inserted radially in the container at one or both axial end portions of the container, which cotter member or pin serves as a structure for bearing an axial force induced by a high pressure load; and a plurality of flexible members wound round the outer periphery of the container axially of the latter to thereby exert a precompression on the entirety of the container.

    摘要翻译： 一种高压装置，包括内部设置有能够关闭的圆筒形空间的容器，该容器由整体构件或在整个轴向长度上连接的多个构件的整体组件构成; 在容器的一个或两个轴向端部处径向插入容器中的开口部件或销，该开口部件或销用作用于承受由高压负荷引起的轴向力的结构; 以及多个柔性构件，其围绕容器的外周边卷绕在容器的外周上，从而在整个容器上施加预压缩。

    Die forging press
    9.
    发明授权
    Die forging press 失效
    锻压机

    公开(公告)号：US4444039A

    公开(公告)日：1984-04-24

    申请号：US371921

    申请日：1982-04-26

    申请人： Akira Asari ,  Toshio Kurosaki

    发明人： Akira Asari ,  Toshio Kurosaki

    IPC分类号： B21J9/02 ,  B21J9/08 ,  B21J13/08 ,  B21K29/00 ,  B21D37/16

    CPC分类号： B21J9/08 ,  B21J13/085 ,  B21J9/02 ,  B21K29/00 ,  Y10S100/918

    摘要： A die forging press which includes a press machine proper adapted to detachably mount a die set having an upper die and a lower die; an auxiliary station having a die opening mechanism for holding and moving the upper and lower dies of the die set toward and away from each other and a heater having a heating head retractably protrudable to a position between the upper and lower dies when opened by the die opening mechanism. A transfer mechanism for transferring a die set between the press machine and auxiliary station is provided.

    摘要翻译： 一种模锻机，包括适于可拆卸地安装具有上模和下模的模组的压力机; 具有用于保持和移动模具的上下模具朝向和远离的模具打开机构的辅助站和具有可由模具打开时可缩回地突出到上模和下模之间的位置的加热头的加热器 开放机制。 提供了一种用于在压机和辅助站之间传送模具组的传送机构。