公开(公告)号：US06214325B1

公开(公告)日：2001-04-10

申请号：US08988534

申请日：1997-12-10

Applicant: Michel Philippe ,  Alain Campos ,  Didier Semeria

Inventor： Michel Philippe ,  Alain Campos ,  Didier Semeria

IPC: A61K706

CPC classification number: A61Q5/02 ,  A61K8/44 ,  A61Q5/12 ,  A61Q19/10 ,  C07C219/06 ,  Y10S514/88 ,  Y10S514/881

Abstract: Hydroxypropyl quaternary ammonium compounds containing an ester function, in particular containing a fatty acid ester function, of formula (I): in which R denotes a branched C7-C35 alkyl chain; R1, R2 and R3 independently denote a C1-C18 alkyl chain; X− denotes a halide or another anion chosen from: in which R4 and R5 independently denote a C1-C8 alkyl chain are disclosed. Cosmetic or dermatological compositions containing these compounds, in particular haircare products in which the quaternary compounds are used as treatment agents for improving the surface condition of the hair as well as for protecting the hair under the action of atmospheric agents or mechanical or chemical treatments are disclosed.

Abstract translation: 含有酯官能团的羟丙基季铵化合物，特别是含有式（I）的脂肪酸酯官能团：其中R表示支链C7-C35烷基链; R1，R2和R3独立地表示C1-C18烷基链; X-表示卤素或选自其中的另一阴离子：其中R4和R5独立地表示C1-C8烷基链。 公开了包含这些化合物的化妆品或皮肤病学组合物，特别是其中使用四元化合物作为用于改善头发表面状态的治疗剂以及在大气剂或机械或化学处理作用下保护毛发的护发产品 。

公开(公告)号：US6046344A

公开(公告)日：2000-04-04

申请号：US988216

申请日：1997-12-10

Applicant: Michel Philippe ,  Alain Campos

Inventor： Michel Philippe ,  Alain Campos

IPC: C07C213/00 ,  C07C213/10 ,  C07C219/02 ,  C07C219/06 ,  C07C303/24 ,  C07C303/32 ,  C07C303/44 ,  C07C305/06 ,  C07C305/14 ,  C07C309/04 ,  C07C309/20 ,  C07F9/11 ,  C07F9/113 ,  C07C227/00

CPC classification number: C07C213/00

Abstract: A process for the preparation of hydroxypropylated quaternary ammonium compounds containing an ester functional group, preferably a fatty acid ester functional group, of formula (I): ##STR1## in which: R denotes a saturated or unsaturated, linear or branched C.sub.7 -C.sub.35 alkyl chain;R.sub.1, R.sub.2 and R.sub.3 independently denote a saturated or unsaturated, linear or branched C.sub.1 -C.sub.18 alkyl chain;X.sup.- denotes a halide or another anion chosen from: ##STR2## in which: R.sub.4 and R.sub.5 independently denote a saturated or unsaturated, linear or branched C.sub.1 -C.sub.8 alkyl chain, wherein the process comprises reacting, in a single step and in an alcoholic solvent at reflux, an aliphatic carboxylic acid (RCOOH) salt or an aliphatic carboxylic acid under basic catalysis conditions with a compound of formula (II): ##STR3## in which R.sub.1, R.sub.2, R.sub.3 and X.sup.- are defined as above.

Abstract translation: 制备含有式（I）的酯官能团，优选脂肪酸酯官能团的羟丙基化季铵化合物的方法：其中：R表示饱和或不饱和的直链或支链C 7 -C 35烷基链; R1，R2和R3独立地表示饱和或不饱和的直链或支链C1-C18烷基链; X-表示选自以下的卤化物或另一阴离子：其中：R 4和R 5独立地表示饱和或不饱和的直链或支链C 1 -C 8烷基链，其中所述方法包括在单一步骤和在醇溶剂中在回流下 ，碱性催化条件下的脂族羧酸（RCOOH）盐或脂族羧酸与式（II）化合物反应：其中R 1，R 2，R 3和X如上定义。