-
1.发明授权公开(公告)号：US09339650B2
公开(公告)日：2016-05-17
申请号：US13365549
申请日：2012-02-03
申请人： Ali Rezai , Andre Machado , Keith Carlton
发明人： Ali Rezai , Andre Machado , Keith Carlton
CPC分类号： A61N1/36103 , A61N1/00 , A61N1/0529 , A61N1/36 , A61N1/36067 , A61N1/37229
摘要： A method is provided for neuromodulation to treat stroke. One step of the method includes recording an input waveform from a first site in the nervous system in a source subject. The first site is healthy or at least partially functioning. Next, an output waveform is applied to a second site in the nervous system of a target subject suffering from the stoke. The second site is diseased due to the stroke.
摘要翻译： 提供神经调节治疗中风的方法。 该方法的一个步骤包括从源对象中的神经系统中的第一位点记录输入波形。 第一个网站是健康的或至少部分功能。 接下来，输出波形被施加到遭受脚蹬的目标对象的神经系统中的第二位置。 第二个部位由于中风而患病。
-
2.发明授权Neural stimulation delivery device with independently moveable delivery structures 有权具有独立可移动输送结构的神经刺激输送装置公开(公告)号：US07831308B2
公开(公告)日：2010-11-09
申请号：US10502348
申请日：2003-01-31
申请人： Ali Rezai , Ashwini Sharan
发明人： Ali Rezai , Ashwini Sharan
IPC分类号： A61N1/372
CPC分类号： A61N1/0534 , A61N1/0531 , A61N1/0539
摘要： The present invention relates to a neural stimulation delivery device to deliver electrical and/or chemical stimulation to target sites in the central and peripheral nervous system. The device generally includes a tubular body defining a plurality of ports along the longitudinal axis thereof, a plurality of delivery structures insertable in the body, and a control mechanism in communication with the plurality of delivery structures to independently move each of the plurality of delivery structures through a respective one of the plurality of ports with respect to each other of the plurality of delivery structures. The ability of each delivery structure to be independently moveable through a respective port allows each delivery structure to be selectively advanced or retracted independent of the movement of another delivery structure.
摘要翻译： 本发明涉及一种神经刺激递送装置，用于向中枢和周围神经系统的靶位点递送电和/或化学刺激。 该装置通常包括：管状体，其沿其纵向轴线限定多个端口;多个输送结构，其可插入本体;以及控制机构，与所述多个输送结构连通，以独立地移动所述多个输送结构 通过所述多个端口中的相应一个端口相对于所述多个递送结构中的彼此。 每个输送结构独立地通过相应端口可移动的能力允许独立于另一个输送结构的运动而选择性地提前或缩回每个输送结构。
-
公开(公告)号：US07532938B2
公开(公告)日：2009-05-12
申请号：US11222774
申请日：2005-09-12
申请人： Sandra Machado , Andre Machado , Ali Rezai
发明人： Sandra Machado , Andre Machado , Ali Rezai
IPC分类号： A61N1/05
CPC分类号： A61N1/32 , A61B5/0215 , A61B5/029 , A61B5/412 , A61N1/05 , A61N1/0558
摘要： A minimally invasive intraluminal electrode assembly that includes a cannulated tube and a plurality of wires disposed within the cannulated tube. Each of the plurality of wires has one of a plurality of electrical contacts on a distal end thereof. The distal portion of the plurality of wires assumes a radially constrained configuration within the cannulated tube in a retracted position and a radially extended position outward of the cannulated tube in a deployed position. The electrode assembly further comprises a spring electrode connecting the plurality of electrical contacts to collectively form a substantially circular configuration in a deployed position.
摘要翻译： 一种微创管腔内电极组件，其包括插管和设置在插管内的多根线。 多个电线中的每一个在其远端具有多个电接触中的一个。 多根丝线的远端部分在缩回位置内的管状管内呈径向约束的构型，并且在展开位置中呈放射状延伸位置。 电极组件还包括连接多个电触头的弹簧电极，以在展开位置中共同形成大致圆形的构造。
-
4.发明申请公开(公告)号：US20050161052A1
公开(公告)日：2005-07-28
申请号：US10502611
申请日：2003-01-31
申请人： Ali Rezai , Ashwini Sharan
发明人： Ali Rezai , Ashwini Sharan
IPC分类号： A61B20060101 , A61B19/00 , A61M20060101 , A61M3/00
摘要： A method and apparatus (10) for advancing a device (12) underneath the skin (102) in a mammalian body comprises a casing (50) made of a magnetic material. The casing (50) has a closed tip (64) at one end and an aperture (65) in an opposite end. The casing (50) includes an annular inner surface (70) that defines a cavity (76) within the casing for receiving a device (12) that projects through the aperture (65). The casing (50) further includes structure for attaching to the device (12). The casing (50) is operable to advance the device (12) through tissue (100) underlying the skin (102) in response to movement of a magnetic field across the skin.
摘要翻译： 用于使哺乳动物体内的皮肤（102）下方的装置（12）前进的方法和装置（10）包括由磁性材料制成的壳体（50）。 壳体（50）在一端具有封闭的尖端（64）和相对端的孔（65）。 壳体（50）包括在壳体内限定空腔（76）的环形内表面（70），用于接收突出穿过孔（65）的装置（12）。 壳体（50）还包括用于附接到装置（12）的结构。 壳体（50）可操作以响应于穿过皮肤的磁场的移动而将装置（12）推进穿过皮肤（102）下方的组织（100）。
-
公开(公告)号：US20050131506A1
公开(公告)日：2005-06-16
申请号：US10503160
申请日：2003-02-03
申请人： Ali Rezai , Ashwini Sharan
发明人： Ali Rezai , Ashwini Sharan
CPC分类号： A61N1/0553 , A61N1/0531 , A61N1/0534 , A61N1/36071 , A61N1/375 , G06F9/4494
摘要： A device and method for stimulating neural tissue in a patient comprising: providing a lead having opposed first and second ends defining a longitudinal axis therebetween wherein the lead having at least one electrode provided thereon for delivering electrical stimulation; implanting the lead adjacent the neural tissue; applying electrical signals to the at least one electrode to provide electrical stimulation to the neural tissue; closing all incisions made to implant the lead so that the lead is completely implanted in the patient; and adjusting, at any time after the step of closing all the incisions, the position of the lead so that it moves in a direction substantially perpendicular to the longitudinal axis of the lead.
摘要翻译： 一种用于刺激患者中的神经组织的装置和方法，包括：提供具有相对的第一和第二端的引线，所述第一和第二端在其间限定纵向轴线，其中所述引线具有设置在其上的至少一个电极， 将铅插入邻近神经组织; 将电信号施加到所述至少一个电极以向所述神经组织提供电刺激; 关闭所有切口以植入引线，使铅完全植入患者; 并且在关闭所有切口的步骤之后的任何时间调整引线的位置，使得其在基本上垂直于引线的纵向轴线的方向上移动。
-
公开(公告)号：US20050065574A1
公开(公告)日：2005-03-24
申请号：US10900301
申请日：2004-07-28
申请人： Ali Rezai
发明人： Ali Rezai
CPC分类号： A61N1/18 , A61N1/205 , A61N1/36071
摘要： The present invention relates to a method of affecting a hypothalamic-related condition by electrically and/or chemically stimulating the hypothalamus. Also provided are methods of stimulating a hypothalamic-related target site by responding to a sensor signal relating to a physiological activity of the body associated with the hypothalamic-related condition desired to be affected. The present invention also describes a method of directly or indirectly modulating hormones synthesized or released by the hypothalamus to affect hypothalamic-related conditions involving hormonal function, dysfunction or imbalance.
摘要翻译： 本发明涉及通过电和/或化学刺激下丘脑来影响下丘脑相关病症的方法。 还提供了通过响应与期望受影响的与下丘脑相关病症相关的身体的生理活性相关的传感器信号来刺激下丘脑相关靶位点的方法。 本发明还描述了直接或间接调节由下丘脑合成或释放的激素以影响涉及激素功能，功能障碍或不平衡的下丘脑相关病症的方法。
-
公开(公告)号：US20050065573A1
公开(公告)日：2005-03-24
申请号：US10989489
申请日：2004-11-17
申请人： Ali Rezai
发明人： Ali Rezai
CPC分类号： A61N1/0553 , A61N1/05 , A61N1/0509 , A61N1/326 , A61N1/36007 , A61N1/36017 , A61N1/36021 , A61N1/36071
摘要： The present invention provides a method of affecting physiological disorders by stimulating a specific location along the sympathetic nerve chain. Preferably, the present invention provides a method of affecting a variety of physiological disorders or pathological conditions by placing an electrode adjacent to or in communication with at least one ganglion along the sympathetic nerve chain and stimulating the at least one ganglion until the physiological disorder or pathological condition has been affected.
-
公开(公告)号：US20050010262A1
公开(公告)日：2005-01-13
申请号：US10502349
申请日：2003-01-31
申请人： Ali Rezai , Ashwini Sharan
发明人： Ali Rezai , Ashwini Sharan
IPC分类号： A61N20060101 , A61N1/05 , A61N1/18 , A61N1/34 , A61N1/36
CPC分类号： A61N1/36071
摘要： The present invention relates to methods of affecting chronic pain by electrically and/or chemically stimulating target sites of the pain circuitry associated with chronic pain. Such target sites include cerebral target sites, including limbic structures, associated with the emotional and suffering components of chronic pain, as well as deep brain target sites associated with the affective and sensory components of chronic pain. Also provided is a method of affecting chronic pain by stimulating a target site of the pain circuitry associated with chronic pain to stimulate the synthesis or release of endogenous opioids.
摘要翻译： 本发明涉及通过电和/或化学刺激与慢性疼痛相关的疼痛电路的靶位点来影响慢性疼痛的方法。 这些目标地点包括与慢性疼痛的情绪和痛苦成分相关的脑部靶点，包括边缘结构，以及与慢性疼痛的情感和感觉成分相关的深层脑靶点。 还提供了通过刺激与慢性疼痛相关的疼痛电路的靶位点以刺激内源性阿片样物质的合成或释放而影响慢性疼痛的方法。
-
9.发明申请公开(公告)号：US20120136410A1
公开(公告)日：2012-05-31
申请号：US13365549
申请日：2012-02-03
申请人： Ali Rezai , Andre Machado , Keith Carlton
发明人： Ali Rezai , Andre Machado , Keith Carlton
IPC分类号： A61N1/36
CPC分类号： A61N1/36103 , A61N1/00 , A61N1/0529 , A61N1/36 , A61N1/36067 , A61N1/37229
摘要： A method is provided for neuromodulation to treat stroke. One step of the method includes recording an input waveform from a first site in the nervous system in a source subject. The first site is healthy or at least partially functioning. Next, an output waveform is applied to a second site in the nervous system of a target subject suffering from the stoke. The second site is diseased due to the stroke.
摘要翻译： 提供神经调节治疗中风的方法。 该方法的一个步骤包括从源对象中的神经系统中的第一位置记录输入波形。 第一个网站是健康的或至少部分功能。 接下来，输出波形被施加到遭受脚蹬的目标对象的神经系统中的第二位置。 第二个部位由于中风而患病。
-
10.发明授权公开(公告)号：US08112154B2
公开(公告)日：2012-02-07
申请号：US11943344
申请日：2007-11-20
申请人： Ali Rezai , Andre Machado , Keith Carlton
发明人： Ali Rezai , Andre Machado , Keith Carlton
IPC分类号： A61N1/05
CPC分类号： A61N1/36067 , A61B5/0476 , A61B5/11 , A61B5/1106 , A61B5/4047 , A61B5/4052 , A61B5/6814 , A61N1/0529 , A61N1/36071
摘要： Methods for neuromodulation using waveform signals. In certain embodiments, an input waveform is obtained from a signal source site in a source subject and an output waveform is applied to a target site in a target subject. The source subject is a human or animal and the signal source site is in the nervous system, including the brain. The source subject and target subject are the same subjects or different subjects. The output waveform is identical to the input waveform or derived from the input waveform. In some embodiments, the output waveform is modified in response to physiologic feedback. Also provided are systems for neuromodulation using waveform signals.
摘要翻译： 使用波形信号进行神经调节的方法。 在某些实施例中，从源对象中的信号源站点获得输入波形，并且将输出波形应用于目标对象中的目标位置。 来源主题是人或动物，信号源位置在神经系统中，包括大脑。 来源科目和目标科目是相同的科目或不同科目。 输出波形与输入波形相同或从输入波形导出。 在一些实施例中，响应于生理反馈修改输出波形。 还提供了使用波形信号进行神经调节的系统。
-
-
-
-
-
-
-
-
-
搜索结果
46 条记录 (耗时 0.022 秒)
