Re-usable elements of a configuration model
    1.
    发明授权
    Re-usable elements of a configuration model 有权
    配置模型的可重用元素

    公开(公告)号:US06988014B2

    公开(公告)日:2006-01-17

    申请号:US10366627

    申请日:2003-02-12

    IPC分类号: G06F19/00

    摘要: Methods and apparatus, including computer program products, for a multi-purpose configuration model. A computer program product, tangibly stored on a machine-readable medium, for defining a configuration model for a configurable product, includes instructions operable to cause a programmable processor to receive input. The product includes instructions to define, based on the input, a base component of the configuration model, the base component including information that describes the product. The product includes instructions to include, as a child object of the base component, a reused subcomponent that was previously defined, the reused subcomponent including information that describes the product.

    摘要翻译: 方法和设备,包括计算机程序产品,用于多用途配置模型。 有形地存储在机器可读介质上的用于定义可配置产品的配置模型的计算机程序产品包括可操作以使可编程处理器接收输入的指令。 该产品包括基于输入定义配置模型的基本组件的指令,基本组件包括描述产品的信息。 该产品包括作为基础组件的子对象包括之前定义的重用子组件的指令,重用的子组件包括描述产品的信息。

    Method of performing three-dimensional molecular superposition and similarity searches in databases of flexible molecules
    2.
    发明授权
    Method of performing three-dimensional molecular superposition and similarity searches in databases of flexible molecules 有权
    在柔性分子数据库中执行三维分子叠加和相似性检索的方法

    公开(公告)号:US07672791B2

    公开(公告)日:2010-03-02

    申请号:US10462056

    申请日:2003-06-13

    IPC分类号: G06F17/00 G06G7/58

    CPC分类号: G06F19/705

    摘要: The virtual screening of a database of molecules is based on explicit three-dimensional molecular superpositions. The torsional flexibility of the database molecules is taken fully into account, and an arbitrary number of conformation-dependent molecular features may be considered. A fragmentation-reassembly approach is utilized, which allows for an efficient sampling of the conformational space. A fast clique-based pattern-matching algorithm generates alignments of pairs of adjacent molecular fragments on the (rigid) query molecule that are subsequently reassembled to complete database molecules. Using conventional molecular features (hydrogen bond donors and acceptors, charges, and hydrophobic groups), it is possible to rapidly produce accurate alignments of medium-sized drug-like molecules. Examples with a test database containing a diverse set of 1780 drug-like molecules (including all conformers) show that average query processing times of the order of 0.1 seconds per molecule can be achieved on a PC, depending on the size of the query molecule.

    摘要翻译: 分子数据库的虚拟筛选基于显式的三维分子叠加。 充分考虑数据库分子的扭转灵活性,并且可以考虑任意数量的构象依赖性分子特征。 利用碎片重组方法,可以对构象空间进行有效的采样。 基于快速基于组合的模式匹配算法产生对(刚性)查询分子上的相邻分子片段对的比对,随后重新组装以完成数据库分子。 使用常规分子特征(氢键供体和受体,电荷和疏水基团),可以快速产生中等大小的药物样分子的精确对准。 包含1780种药物样分子(包括所有构象异构体)的测试数据库的示例显示,根据查询分子的大小,可以在PC上实现每分子0.1秒的平均查询处​​理时间。

    COUNTERTOP CONNECTING FASTENER SECURING DEVICE
    3.
    发明申请
    COUNTERTOP CONNECTING FASTENER SECURING DEVICE 审中-公开
    计数器连接紧固件安全装置

    公开(公告)号:US20090010733A1

    公开(公告)日:2009-01-08

    申请号:US12127796

    申请日:2008-05-27

    IPC分类号: F16B37/04

    摘要: A countertop connecting fastener securing device, comprising: a first portion, wherein the first portion abuts a countertop section, wherein the first portion engages the countertop section to apply a force in a first direction; a second portion, wherein the second portion abuts the countertop section, wherein the second portion engages the countertop section to apply a force in a second direction, wherein the second direction is a direction that is different from the first direction; and a fastener connection, wherein the fastener connection couples the countertop connecting fastener securing device to a countertop connecting fastener.

    摘要翻译: 一种台面连接紧固件固定装置,包括:第一部分,其中第一部分邻接台面部分,其中第一部分接合台面部分以在第一方向上施加力; 第二部分,其中第二部分邻接台面部分,其中第二部分接合台面部分以在第二方向施加力,其中第二方向是不同于第一方向的方向; 和紧固件连接件,其中所述紧固件连接件将所述对接件连接紧固件固定装置连接到对接件连接紧固件。

    Versioning of elements in a configuration model
    4.
    发明授权
    Versioning of elements in a configuration model 有权
    配置模型中元素的版本控制

    公开(公告)号:US07930149B2

    公开(公告)日:2011-04-19

    申请号:US10742506

    申请日:2003-12-19

    IPC分类号: G06F17/50

    摘要: Methods and apparatus, including computer program products, for a multi-purpose configuration model. A computer program product for defining a configuration model for a configurable product includes instructions operable to cause a programmable processor to receive a first input, and define, based on the first input, a first version of a first subcomponent to be used in the configuration model, the first version including information that describes the configurable product. The computer program product includes instructions to receive a second input, and define, based on the second input, a second version of the first subcomponent to be used in the configuration model, the second version including information that describes the configurable product. The computer program product designates one of the first or second versions to be an active version, and designates the other to be an inactive version. The computer program product also includes instructions to define a first component based at least in part on the active version.

    摘要翻译: 方法和设备,包括计算机程序产品,用于多用途配置模型。 用于定义可配置产品的配置模型的计算机程序产品包括可操作以使可编程处理器接收第一输入并且基于第一输入定义要在配置模型中使用的第一子组件的第一版本的指令 ,第一个版本包括描述可配置产品的信息。 计算机程序产品包括接收第二输入的指令,并且基于第二输入定义要在配置模型中使用的第一子组件的第二版本,第二版本包括描述可配置产品的信息。 计算机程序产品将第一或第二版本中的一个指定为活动版本,并将另一个指定为不活动版本。 计算机程序产品还包括至少部分地基于活动版本来定义第一组件的指令。

    Versioning of elements in a configuration model
    5.
    发明申请
    Versioning of elements in a configuration model 有权
    配置模型中元素的版本控制

    公开(公告)号:US20050137731A1

    公开(公告)日:2005-06-23

    申请号:US10742506

    申请日:2003-12-19

    IPC分类号: G06F19/00

    摘要: Methods and apparatus, including computer program products, for a multi-purpose configuration model. A computer program product for defining a configuration model for a configurable product includes instructions operable to cause a programmable processor to receive a first input, and define, based on the first input, a first version of a first subcomponent to be used in the configuration model, the first version including information that describes the product. The product includes instructions to receive a second input, and define, based on the second input, a second version of the first subcomponent to be used in the configuration model, the second version including information that describes the product. The product designates one of the first or second versions to be an active version, and designates the other to be an inactive version. The product also includes instructions to define a first component based at least in part on the active version.

    摘要翻译: 方法和设备,包括计算机程序产品,用于多用途配置模型。 用于定义可配置产品的配置模型的计算机程序产品包括可操作以使可编程处理器接收第一输入并且基于第一输入定义要在配置模型中使用的第一子组件的第一版本的指令 ,第一个版本包括描述该产品的信息。 该产品包括接收第二输入的指令,并且基于第二输入定义要在配置模型中使用的第一子组件的第二版本,第二版本包括描述产品的信息。 该产品将第一或第二版本中的一个指定为活动版本,并将另一个版本指定为不活动版本。 该产品还包括至少部分地基于活动版本来定义第一组件的指令。