摘要:
Methods and apparatus, including computer program products, for a multi-purpose configuration model. A computer program product, tangibly stored on a machine-readable medium, for defining a configuration model for a configurable product, includes instructions operable to cause a programmable processor to receive input. The product includes instructions to define, based on the input, a base component of the configuration model, the base component including information that describes the product. The product includes instructions to include, as a child object of the base component, a reused subcomponent that was previously defined, the reused subcomponent including information that describes the product.
摘要:
The virtual screening of a database of molecules is based on explicit three-dimensional molecular superpositions. The torsional flexibility of the database molecules is taken fully into account, and an arbitrary number of conformation-dependent molecular features may be considered. A fragmentation-reassembly approach is utilized, which allows for an efficient sampling of the conformational space. A fast clique-based pattern-matching algorithm generates alignments of pairs of adjacent molecular fragments on the (rigid) query molecule that are subsequently reassembled to complete database molecules. Using conventional molecular features (hydrogen bond donors and acceptors, charges, and hydrophobic groups), it is possible to rapidly produce accurate alignments of medium-sized drug-like molecules. Examples with a test database containing a diverse set of 1780 drug-like molecules (including all conformers) show that average query processing times of the order of 0.1 seconds per molecule can be achieved on a PC, depending on the size of the query molecule.
摘要:
A countertop connecting fastener securing device, comprising: a first portion, wherein the first portion abuts a countertop section, wherein the first portion engages the countertop section to apply a force in a first direction; a second portion, wherein the second portion abuts the countertop section, wherein the second portion engages the countertop section to apply a force in a second direction, wherein the second direction is a direction that is different from the first direction; and a fastener connection, wherein the fastener connection couples the countertop connecting fastener securing device to a countertop connecting fastener.
摘要:
Methods and apparatus, including computer program products, for a multi-purpose configuration model. A computer program product for defining a configuration model for a configurable product includes instructions operable to cause a programmable processor to receive a first input, and define, based on the first input, a first version of a first subcomponent to be used in the configuration model, the first version including information that describes the configurable product. The computer program product includes instructions to receive a second input, and define, based on the second input, a second version of the first subcomponent to be used in the configuration model, the second version including information that describes the configurable product. The computer program product designates one of the first or second versions to be an active version, and designates the other to be an inactive version. The computer program product also includes instructions to define a first component based at least in part on the active version.
摘要:
Methods and apparatus, including computer program products, for a multi-purpose configuration model. A computer program product for defining a configuration model for a configurable product includes instructions operable to cause a programmable processor to receive a first input, and define, based on the first input, a first version of a first subcomponent to be used in the configuration model, the first version including information that describes the product. The product includes instructions to receive a second input, and define, based on the second input, a second version of the first subcomponent to be used in the configuration model, the second version including information that describes the product. The product designates one of the first or second versions to be an active version, and designates the other to be an inactive version. The product also includes instructions to define a first component based at least in part on the active version.