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    Methods for making leads with segmented electrodes for electrical stimulation systems
    2.
    发明授权
    Methods for making leads with segmented electrodes for electrical stimulation systems 有权
    用于电刺激系统的分段电极的引线方法

    公开(公告)号：US08560085B2

    公开(公告)日：2013-10-15

    申请号：US13369013

    申请日：2012-02-08

    申请人： Michael Adam Moffitt ,  Anne Margaret Pianca ,  Andrew DiGiore

    发明人： Michael Adam Moffitt ,  Anne Margaret Pianca ,  Andrew DiGiore

    IPC分类号： A61N1/00

    CPC分类号： A61N1/0529 ,  A61B2090/3937 ,  A61B2090/3966 ,  A61N1/0534 ,  A61N1/086 ,  A61N1/36182

    摘要： One embodiment is a stimulation lead including a lead body comprising a longitudinal surface, a distal end, and a proximal end; and multiple electrodes disposed along the longitudinal surface of the lead body near the distal end of the lead body. The multiple electrodes include multiple segmented electrodes. At least a first portion of the lead body, proximal to the electrodes, is transparent or translucent and at least a second portion of the lead body, separating two or more of the segmented electrodes, is opaque so that the segmented electrodes separated by the second portion of the lead body are visually distinct. Alternatively or additionally, the stimulation lead can include an indicator ring, a stripe, a groove, or a marking aligned with one or more of the segmented electrodes.

    摘要翻译： 一个实施例是包括包括纵向表面，远端和近端的引线主体的刺激引线; 以及沿引线本体的远端的纵向表面设置的多个电极。 多个电极包括多个分段电极。 引线本体的至少靠近电极的第一部分是透明或半透明的，并且分离两个或更多个分段电极的引线体的至少第二部分是不透明的，使得分段电极被第二部分分开 铅体的部分在视觉上不同。 或者或另外，刺激引线可以包括与一个或多个分段电极对准的指示环，条纹，凹槽或标记。

    System and method for avoiding, reversing, and managing neurological accommodation to electrical stimulation
    4.
    发明授权
    System and method for avoiding, reversing, and managing neurological accommodation to electrical stimulation 有权
    用于避免，逆转和管理神经系统适应电刺激的系统和方法

    公开(公告)号：US08315707B2

    公开(公告)日：2012-11-20

    申请号：US13423245

    申请日：2012-03-18

    申请人： Kristen Jaax ,  Andrew DiGiore

    发明人： Kristen Jaax ,  Andrew DiGiore

    IPC分类号： A61N1/00

    CPC分类号： A61N1/37235 ,  A61N1/36132 ,  A61N1/36146 ,  A61N1/37264

    摘要： A method of operating a neurostimulation device comprises varying a first stimulation parameter under user control while fixing a second stimulation parameter, generating a plurality of stimulation parameter sets from the varied first stimulation parameter and the fixed second stimulation parameter, outputting a pulsed electrical waveform from the neurostimulation device between electrodes in accordance with the stimulation parameter sets, such that a therapeutic effect is achieved while allowing neural tissue to undergo neurological accommodation, changing the second stimulation parameter, varying the first stimulation parameter under user control while fixing the second changed stimulation parameter, generating another plurality of stimulation parameter sets from the varied first stimulation parameter and the fixed changed second stimulation parameter, and outputting the pulsed electrical waveform from the neurostimulation device between the electrodes in accordance with the other stimulation parameter sets to maintain the therapeutic effect while the neural tissue is neurologically accommodated.

    摘要翻译： 操作神经刺激装置的方法包括在固定第二刺激参数的同时改变用户控制下的第一刺激参数，从变化的第一刺激参数和固定的第二刺激参数产生多个刺激参数集，输出来自 神经刺激装置，根据刺激参数组，使得在允许神经组织经历神经学调节的同时实现治疗效果，改变第二刺激参数，在固定第二改变的刺激参数的同时改变用户控制下的第一刺激参数， 从变化的第一刺激参数和固定改变的第二刺激参数产生另外多个刺激参数集合，并且根据另一个st从电极之间的神经刺激装置输出脉冲电波形 模拟参数集，以在神经组织神经学适应的同时保持治疗效果。

    ANCHORING UNITS FOR LEADS OF IMPLANTABLE ELECTRIC STIMULATION SYSTEMS AND METHODS OF MAKING AND USING
    5.
    发明申请
    ANCHORING UNITS FOR LEADS OF IMPLANTABLE ELECTRIC STIMULATION SYSTEMS AND METHODS OF MAKING AND USING 有权
    可植入电刺激系统引导锚固单元及其制造和使用方法

    公开(公告)号：US20110295330A1

    公开(公告)日：2011-12-01

    申请号：US13207876

    申请日：2011-08-11

    申请人： Brett Schleicher ,  Andrew DiGiore ,  Rafael Carbunaru ,  Courtney Lane ,  Kristen N. Jaax

    发明人： Brett Schleicher ,  Andrew DiGiore ,  Rafael Carbunaru ,  Courtney Lane ,  Kristen N. Jaax

    IPC分类号： A61N1/36 ,  A61N1/05

    CPC分类号： A61N1/0558

    摘要： A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.

    摘要翻译： 神经刺激引线具有远端，近端和纵向长度。 神经刺激引线包括设置在远端的多个电极，设置在近端的多个端子，以及将多个电极电连接到多个端子的多个导线。 神经刺激引线还包括设置在神经刺激引线上的至少一个锚定单元。 所述至少一个锚定单元被配置和布置成用于将神经刺激引线抵靠骨结构锚定。

    BURR HOLE SEALING DEVICE FOR PREVENTING BRAIN SHIFT
    7.
    发明申请
    BURR HOLE SEALING DEVICE FOR PREVENTING BRAIN SHIFT 有权
    用于预防脑移位的双孔密封装置

    公开(公告)号：US20110054518A1

    公开(公告)日：2011-03-03

    申请号：US12549174

    申请日：2009-08-27

    申请人： Rafael Carbunaru ,  Todd K. Whitehurst ,  Andrew DiGiore ,  Kristen Jaax

    发明人： Rafael Carbunaru ,  Todd K. Whitehurst ,  Andrew DiGiore ,  Kristen Jaax

    IPC分类号： A61B17/08 ,  A61M5/00

    CPC分类号： A61N1/0539 ,  A61B17/3415 ,  A61B90/14 ,  A61B2017/3419 ,  A61B2090/103 ,  A61M2039/025 ,  A61M2039/0276 ,  A61M2039/0282

    摘要： A burr hole sealing device for preventing brain shift during a stimulation lead implantation procedure is provided. The device includes a suction cup ring and a self-sealing membrane positioned within the aperture of the ring. The sealing device is attached adjacent to a burr hole and over a dura layer that is exposed in the bottom of the burr hole. The stimulation lead is disposed through the burr hole, through the membrane, through the dura layer and into brain tissue. The membrane is configured to allow the lead to pass therethrough while maintaining a tight seal around the diameter of the lead, thereby hindering leakage of cerebrospinal fluid out of the cranial cavity and maintaining a substantially fixed intracranial pressure. In one embodiment, the sealing device includes a syringe for adding fluid to, or removing fluid from, the cranial cavity in response to a detected change in intracranial pressure.

    摘要翻译： 提供了一种用于在刺激引线植入程序期间防止脑移位的钻孔密封装置。 该装置包括吸盘环和位于环的孔内的自密封膜。 密封装置邻近毛刺孔并暴露在钻孔底部的硬脑膜层上。 刺激引线通过毛刺孔穿过膜，穿过硬脑膜层并进入脑组织。 膜被配置为允许引线通过，同时保持围绕铅直径的紧密密封，从而阻止脑脊液从脑腔中泄漏并保持基本上固定的颅内压。 在一个实施例中，密封装置包括用于响应于检测到的颅内压变化而将流体添加到颅腔或从头颅腔移除流体的注射器。

    ANCHORING UNITS FOR LEADS OF IMPLANTABLE ELECTRIC STIMULATION SYSTEMS AND METHODS OF MAKING AND USING
    8.
    发明申请
    ANCHORING UNITS FOR LEADS OF IMPLANTABLE ELECTRIC STIMULATION SYSTEMS AND METHODS OF MAKING AND USING 有权
    可植入电刺激系统引导锚固单元及其制造和使用方法

    公开(公告)号：US20090248095A1

    公开(公告)日：2009-10-01

    申请号：US12413081

    申请日：2009-03-27

    申请人： Brett Schleicher ,  Andrew DiGiore ,  Rafael Carbunaru ,  Courtney Lane ,  Kristen N. Jaax

    发明人： Brett Schleicher ,  Andrew DiGiore ,  Rafael Carbunaru ,  Courtney Lane ,  Kristen N. Jaax

    IPC分类号： A61N1/00 ,  A61N1/04

    CPC分类号： A61N1/0558

    摘要： A nerve stimulation lead has a distal end, a proximal end, and a longitudinal length. The nerve stimulation lead includes a plurality of electrodes disposed at the distal end, a plurality of terminals disposed at the proximal end, and a plurality of conductive wires electrically coupling the plurality of electrodes electrically to the plurality of terminals. The nerve stimulation lead also includes at least one anchoring unit disposed on the nerve stimulation lead. The at least one anchoring unit is configured and arranged for anchoring the nerve stimulation lead against a bony structure.

    摘要翻译： 神经刺激引线具有远端，近端和纵向长度。 神经刺激引线包括设置在远端的多个电极，设置在近端的多个端子，以及将多个电极电连接到多个端子的多个导线。 神经刺激引线还包括设置在神经刺激引线上的至少一个锚定单元。 所述至少一个锚定单元被配置和布置成用于将神经刺激引线抵靠骨结构锚定。

    External charger for an implantable medical device having at least one moveable charging coil
    10.
    发明授权
    External charger for an implantable medical device having at least one moveable charging coil 有权
    用于具有至少一个可移动充电线圈的可植入医疗装置的外部充电器

    公开(公告)号：US08994325B2

    公开(公告)日：2015-03-31

    申请号：US13277522

    申请日：2011-10-20

    申请人： Rafael Carbunaru ,  Andrew DiGiore ,  Todd Whitehurst

    发明人： Rafael Carbunaru ,  Andrew DiGiore ,  Todd Whitehurst

    IPC分类号： H01M10/44 ,  H01M10/46 ,  H02J7/02 ,  H02J7/00 ,  H01F38/14

    CPC分类号： H02J50/40 ,  A61N1/3787 ,  H01F38/14 ,  H02J7/0042 ,  H02J7/025 ,  H02J50/12 ,  H02J50/90

    摘要： Improved external chargers for charging an implantable medical device, and particularly useful in charging a plurality of such devices, are disclosed. Each of the various embodiments include design elements for mechanically manipulating the position of one or more charging coils within the external charger to customize the magnetic charging field as appropriate for the charger/implantable device environment. For example, a single charging coil may be moved within a housing of the external charger to direct the charging field of the coil towards the currently “coldest” implant, i.e., the implant with the lowest coupling to the external charger. The one or more charging coils may be mechanically manipulated within the external charger housing in a number of ways, including by using linear actuators, by inflatable bladders, or even by hand.

    摘要翻译： 公开了改进的用于对植入式医疗装置进行充电的外部充电器，并且对于多个这种装置的充电特别有用。 各种实施例中的每一个都包括用于机械地操纵外部充电器内的一个或多个充电线圈的位置的设计元件，以适应充电器/可植入装置环境来定制磁充电场。 例如，单个充电线圈可以在外部充电器的壳体内移动以将线圈的充电场引向当前“最冷”的植入物，即具有与外部充电器的最低耦合的植入物。 一个或多个充电线圈可以以多种方式在外部充电器壳体内机械地操作，包括通过使用线性致动器，可膨胀气囊，或甚至手动操作。