Concentration gradient profiles for control of agent release rates from polymer matrices
    2.
    发明申请
    Concentration gradient profiles for control of agent release rates from polymer matrices 审中-公开
    用于控制聚合物基质的试剂释放速率的浓度梯度曲线

    公开(公告)号:US20060246109A1

    公开(公告)日:2006-11-02

    申请号:US11119020

    申请日:2005-04-29

    IPC分类号: A61F2/00

    摘要: The present invention generally encompasses the control of the release rate of agents from a polymeric matrix. This control over the release rate of agents provides for control over, inter alia, the therapeutic, prophylactic, diagnostic, and ameliorative effects that are realized by a patient in need of such treatment. In addition, the control of the release rate of agents also has an effect upon the mechanical integrity of the polymeric matrix, as well as a relationship to a subject's absorption rate of the absorbable polymers.

    摘要翻译: 本发明通常包括对来自聚合物基质的试剂的释放速率的控制。 这种对药剂释放速率的控制提供了对需要这种治疗的患者实现的治疗,预防,诊断和改善效果的控制。 此外,试剂的释放速率的控制也对聚合物基质的机械完整性以及与受试者吸收聚合物的吸收速率的关系有影响。

    Apparatus and method for coating stents
    8.
    发明授权
    Apparatus and method for coating stents 有权
    用于涂层支架的装置和方法

    公开(公告)号:US07323209B1

    公开(公告)日:2008-01-29

    申请号:US10438378

    申请日:2003-05-15

    IPC分类号: B05D3/02

    CPC分类号: B05D3/0254 B05B13/0442

    摘要: An apparatus and method is provided for forming coatings on stents. The apparatus includes a temperature adjusting element that can increase or decrease the temperature of the stent. The apparatus can support a stent during the application of a coating composition to the stent. The apparatus can include a mandrel to support a stent and a temperature element integrated with the mandrel to adjust the temperature of the mandrel. The temperature element can include a heating coil or a heating pin, for example, disposed in the mandrel.

    摘要翻译: 提供了用于在支架上形成涂层的装置和方法。 该装置包括能够增加或降低支架温度的温度调节元件。 该装置可以在将涂层组合物施加到支架时支撑支架。 该装置可以包括支撑支架的心轴和与心轴一体化的温度元件以调节心轴的温度。 温度元件可以包括加热线圈或加热销,例如设置在心轴中。

    Packaging sheath for drug coated stent
    9.
    发明申请
    Packaging sheath for drug coated stent 审中-公开
    用于药物涂层支架的包装护套

    公开(公告)号:US20070061001A1

    公开(公告)日:2007-03-15

    申请号:US11225746

    申请日:2005-09-13

    IPC分类号: A61F2/06

    CPC分类号: A61F2/958 A61F2002/9583

    摘要: A sheath for temporarily protecting the drug coating on the surface of a stent after being mounted on a delivery catheter until just before use. The sheath is configured so as to enable its inner diameter to be temporarily increased to facilitate unrestricted fitment about and removal from the stent. Its inner diameter in its relaxed state is selected to be slightly less that the outer diameter of the mounted stent so as to positively grasp the stent and prevent dislodgement.

    摘要翻译: 一种护套,用于在安装在输送导管上之后暂时保护支架表面上的药物涂层,直到使用前。 护套被构造成使得其内径能够被暂时增加,以便于对支架的不受限制的配合和从支架移除。 其松弛状态的内径被选择为稍小于安装的支架的外径,以便正确地抓住支架并防止移位。