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公开(公告)号：US08590567B2
公开(公告)日：2013-11-26
申请号：US13488842
申请日：2012-06-05
IPC分类号： F16K7/00
CPC分类号： F16K27/003 , B01D15/1842 , F16J15/3236 , Y10T137/2224 , Y10T137/7754 , Y10T137/87249 , Y10T137/87885 , Y10T436/117497
摘要： A device to enhance sealing is provided. The device includes a body and a pressure cup. The pressure cup includes a channel, a first pressure channel, and a second pressure channel. The channel is formed in a surface of the body to surround a first portion of the surface. The channel is configured to hold an o-ring. The first pressure channel extends through the body and opens into the first portion of the surface. The second pressure channel extends through the body and opens into the channel. Pneumatic pressure within the second pressure channel is controlled to hold the o-ring in the channel when a second pressure within the first pressure channel changes.
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公开(公告)号：US08807164B2
公开(公告)日：2014-08-19
申请号：US11847971
申请日：2007-08-30
申请人： Joerg Werner Baier , Robert Charles Mierendorf , Anthony Charles Grabski , Andrew Paul Wilke , Anil Rajaram Oroskar
发明人： Joerg Werner Baier , Robert Charles Mierendorf , Anthony Charles Grabski , Andrew Paul Wilke , Anil Rajaram Oroskar
IPC分类号： F16K11/10
CPC分类号： G01N30/44 , B01D15/1821 , B01D15/1842 , B01D15/3804 , G01N30/20 , G01N2030/202 , Y10T137/86509 , Y10T137/86533 , Y10T137/86549 , Y10T137/8667 , Y10T137/87249 , Y10T137/87885
摘要： The present invention provides devices and methods for micro-scale simulated moving bed chromatography (SMB) for continuous preparation of analytic quantities of highly pure fractions of target molecules. The present apparatus and method of the invention is adapted in a preferred embodiment to separations by affinity chromatography involving three discontinuous liquid flow loops. An alternative embodiment of affinity chromatography utilizes standard SMB operating under isocratic conditions.
摘要翻译： 本发明提供用于连续制备分析量高的目标分子的高纯度级分的微尺度模拟移动床层析（SMB）的装置和方法。 本发明的本发明的装置和方法在优选实施方案中适用于通过亲和层析分离，涉及三个不连续的液体流动循环。 亲和层析的另一个实施方案利用在等度条件下操作的标准SMB。
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公开(公告)号：US20120241034A1
公开(公告)日：2012-09-27
申请号：US13488842
申请日：2012-06-05
IPC分类号： G05D7/03
CPC分类号： F16K27/003 , B01D15/1842 , F16J15/3236 , Y10T137/2224 , Y10T137/7754 , Y10T137/87249 , Y10T137/87885 , Y10T436/117497
摘要： A device to enhance sealing is provided. The device includes a body and a pressure cup. The pressure cup includes a channel, a first pressure channel, and a second pressure channel. The channel is formed in a surface of the body to surround a first portion of the surface. The channel is configured to hold an o-ring. The first pressure channel extends through the body and opens into the first portion of the surface. The second pressure channel extends through the body and opens into the channel. Pneumatic pressure within the second pressure channel is controlled to hold the o-ring in the channel when a second pressure within the first pressure channel changes.
摘要翻译： 提供了一种增强密封性的装置。 该装置包括主体和压力杯。 压力杯包括通道，第一压力通道和第二压力通道。 通道形成在主体的表面中以包围表面的第一部分。 通道配置为保持O形环。 第一压力通道延伸穿过主体并且通向表面的第一部分。 第二压力通道延伸穿过主体并且通向通道。 当第一压力通道内的第二压力改变时，第二压力通道内的气压被控制以将O形环保持在通道中。
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公开(公告)号：US20100043891A1
公开(公告)日：2010-02-25
申请号：US12194927
申请日：2008-08-20
IPC分类号： G05D7/03 , G05D16/18 , F16K31/126
CPC分类号： F16K27/003 , B01D15/1842 , F16J15/3236 , Y10T137/2224 , Y10T137/7754 , Y10T137/87249 , Y10T137/87885 , Y10T436/117497
摘要： A device to enhance sealing is provided. The device includes a body and a pressure cup. The pressure cup includes a channel, a first pressure channel, and a second pressure channel. The channel is formed in a surface of the body to surround a first portion of the surface. The channel is configured to hold an o-ring. The first pressure channel extends through the body and opens into the first portion of the surface. The second pressure channel extends through the body and opens into the channel. Pneumatic pressure within the second pressure channel is controlled to hold the o-ring in the channel when a second pressure within the first pressure channel changes.
摘要翻译： 提供了一种增强密封性的装置。 该装置包括主体和压力杯。 压力杯包括通道，第一压力通道和第二压力通道。 通道形成在主体的表面中以包围表面的第一部分。 通道配置为保持O形环。 第一压力通道延伸穿过主体并且通向表面的第一部分。 第二压力通道延伸穿过主体并且通向通道。 当第一压力通道内的第二压力改变时，第二压力通道内的气压被控制以将O形环保持在通道中。
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公开(公告)号：US08196603B2
公开(公告)日：2012-06-12
申请号：US12194927
申请日：2008-08-20
IPC分类号： F16K11/20
CPC分类号： F16K27/003 , B01D15/1842 , F16J15/3236 , Y10T137/2224 , Y10T137/7754 , Y10T137/87249 , Y10T137/87885 , Y10T436/117497
摘要： A device to enhance sealing is provided. The device includes a body and a pressure cup. The pressure cup includes a channel, a first pressure channel, and a second pressure channel. The channel is formed in a surface of the body to surround a first portion of the surface. The channel is configured to hold an o-ring. The first pressure channel extends through the body and opens into the first portion of the surface. The second pressure channel extends through the body and opens into the channel. Pneumatic pressure within the second pressure channel is controlled to hold the o-ring in the channel when a second pressure within the first pressure channel changes.
摘要翻译： 提供了一种增强密封性的装置。 该装置包括主体和压力杯。 压力杯包括通道，第一压力通道和第二压力通道。 通道形成在主体的表面中以包围表面的第一部分。 通道配置为保持O形环。 第一压力通道延伸穿过主体并且通向表面的第一部分。 第二压力通道延伸穿过主体并且通向通道。 当第一压力通道内的第二压力改变时，第二压力通道内的气压被控制以将O形环保持在通道中。
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