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    IMMUNOGENIC APOPTOSIS INDUCING COMPOSITIONS AND METHODS OF USE THEREOF
    1.
    发明申请
    IMMUNOGENIC APOPTOSIS INDUCING COMPOSITIONS AND METHODS OF USE THEREOF 审中-公开
    免疫组织化学诱导组合物及其使用方法

    公开(公告)号：US20130273113A1

    公开(公告)日：2013-10-17

    申请号：US13836617

    申请日：2013-03-15

    Applicant: James R. Baker, JR. ,  Paul Makidon ,  Andrzej Myc

    Inventor： James R. Baker, JR. ,  Paul Makidon ,  Andrzej Myc

    IPC: A61K39/39

    CPC classification number: A61K39/39 ,  A61K39/12 ,  A61K2039/543 ,  A61K2039/55566 ,  C12N2730/10134

    Abstract: The present invention provides methods and compositions for the stimulation of immune responses. In particular, the present invention provides nanoemulsion compositions and methods of using the same for the induction of immune responses (e.g., immunologic cell death/apoptosis (e.g., for the induction of innate and/or adaptive immune responses)). Compositions and methods of the invention find use in, among other things, clinical (e.g. therapeutic and preventative medicine (e.g., for infectious disease, cancer, autoimmunity, and/or tissue injury (e.g., via alteration of host immune responses))) and research applications.

    Abstract translation: 本发明提供了用于刺激免疫应答的方法和组合物。 特别地，本发明提供纳米乳剂组合物及其使用于诱导免疫应答的方法（例如，免疫细胞死亡/凋亡（例如，用于诱导先天和/或适应性免疫应答））。 本发明的组合物和方法尤其可用于临床（例如治疗和预防性药物（例如用于感染性疾病，癌症，自身免疫和/或组织损伤（例如通过改变宿主免疫应答）））和 研究应用。

    Methods of preventing and treating microbial infections
    7.
    发明授权
    Methods of preventing and treating microbial infections 有权
    预防和治疗微生物感染的方法

    公开(公告)号：US06506803B1

    公开(公告)日：2003-01-14

    申请号：US09561111

    申请日：2000-04-28

    Applicant: James R. Baker, Jr. ,  Tarek Hamouda ,  Amy Shih ,  Andrzej Myc

    Inventor： James R. Baker, Jr. ,  Tarek Hamouda ,  Amy Shih ,  Andrzej Myc

    IPC: A01N2500

    CPC classification number: A61K9/1075 ,  A61K45/06 ,  Y02A50/475 ,  Y02A50/481 ,  Y10S514/938

    Abstract: The present invention provides methods and compositions for inactivating bacteria including bacterial spores using an oil-in-water emulsion are provided. The oil-in-water emulsion comprises an oil, a surfactant and an organic phosphate-based solvent. These methods can be used to inactivate a wide variety of microorganisms including bacteria, bacterial spores, fungi, fungal spores and enveloped viruses.

    Abstract translation: 本发明提供了使用水包油乳液灭活包括细菌孢子在内的细菌的方法和组合物。 水包油乳液包含油，表面活性剂和有机磷酸盐基溶剂。 这些方法可用于灭活多种微生物，包括细菌，细菌孢子，真菌，真菌孢子和包膜病毒。

    Antimicrobial compositions and methods of use
    9.
    发明申请
    Antimicrobial compositions and methods of use 审中-公开
    抗微生物组合物和使用方法

    公开(公告)号：US20110091556A1

    公开(公告)日：2011-04-21

    申请号：US11507084

    申请日：2006-08-18

    Applicant: James R. Baker, JR. ,  Tarek Hamouda ,  Amy Shih ,  Andrzej Myc

    Inventor： James R. Baker, JR. ,  Tarek Hamouda ,  Amy Shih ,  Andrzej Myc

    IPC: A61K9/107 ,  A61K31/4425 ,  A61K31/14 ,  A61P31/00

    CPC classification number: A61K9/1075 ,  A61K45/06

    Abstract: The present invention relates to compositions and methods for decreasing the infectivity, morbidity, and rate of mortality associated with a variety of pathogenic organisms and viruses. The present invention also relates to methods and compositions for decontaminating areas colonized or otherwise infected by pathogenic organisms and viruses. Moreover, the present invention relates to methods and compositions for decreasing the infectivity of pathogenic organisms in foodstuffs. In particular, decreased pathogenic organism infectivity, morbidity, and mortality is accomplished by contacting the pathogenic organism with an oil-in-water nanoemulsion comprising an oil, an organic solvent, and a surfactant dispersed in an aqueous phase.

    Abstract translation: 本发明涉及用于降低与各种致病生物体和病毒有关的感染性，发病率和死亡率的组合物和方法。 本发明还涉及用于对由致病菌和病毒定殖或以其它方式感染的区域进行净化的方法和组合物。 此外，本发明涉及用于降低食品中病原生物体的感染性的方法和组合物。 特别地，通过使致病生物与包含分散在水相中的油，有机溶剂和表面活性剂的水包油纳米乳液接触来实现降低的致病生物体的感染性，发病率和死亡率。

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