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    Aneurysm Occlusion Devices
    2.
    发明申请
    Aneurysm Occlusion Devices 审中-公开
    动脉瘤闭塞装置

    公开(公告)号：US20080281350A1

    公开(公告)日：2008-11-13

    申请号：US11956323

    申请日：2007-12-13

    申请人： Ivan Sepetka ,  Greg Mirigian ,  Arindam Datta ,  Steven Hochberg ,  Ricardo Aboytes ,  Trang Ngo

    发明人： Ivan Sepetka ,  Greg Mirigian ,  Arindam Datta ,  Steven Hochberg ,  Ricardo Aboytes ,  Trang Ngo

    IPC分类号： A61M29/02

    CPC分类号： A61B17/12022 ,  A61B17/0057 ,  A61B17/12113 ,  A61B17/12145 ,  A61B17/12172 ,  A61B17/12181 ,  A61B2017/00575 ,  A61B2017/00592 ,  A61B2017/00606 ,  A61B2017/00615 ,  A61B2017/00619 ,  A61B2017/12054 ,  A61B2017/12095 ,  A61M2025/0042

    摘要： An implantable occlusion device for bridging the neck of an aneurysm comprises a biocompatible matrix. The device is movable between a compressed position prior to implantation and a generally concave or cup-shaped position following implantation. The device may comprise a frame having a plurality of elements. The frame elements have a first pre-deployment position generally parallel to a major axis of the delivery lumen, and a second post-deployment position spread radially from the major axis of the delivery lumen. The biocompatible matrix and/or the frame elements may also form or be manipulated to form a generally concave or cupped shape. The matrix can be porous or semiporous, such as a foam or a reticulated matrix. The occlusion device can be folded, twisted and/or stretched to adopt a narrow profile for loading into a coaxial delivery device and expand in place as it adopts its original shape on release. The device may be released or manipulated to a desired shape to occlude an aneurysm. Methods of using the implantable device are also provided.

    摘要翻译： 用于桥接动脉瘤颈部的可植入闭塞装置包括生物相容性基质。 该装置可在植入之前的压缩位置和植入后的大致凹形或杯状位置之间移动。 该装置可以包括具有多个元件的框架。 框架元件具有大致平行于输送腔的长轴的第一预部署位置和从输送腔的长轴径向扩展的第二后部署位置。 生物相容性基质和/或框架元件也可以形成或被操作以形成大体上凹形或杯状的形状。 基质可以是多孔的或半孔的，例如泡沫或网状基质。 闭塞装置可以被折叠，扭曲和/或拉伸以采用狭窄的轮廓以装载到同轴输送装置中，并且在释放时采用其原始形状而扩展就位。 该装置可以被释放或操纵到期望的形状以阻塞动脉瘤。 还提供了使用可植入装置的方法。

    Medical devices containing high inherent viscosity poly(p-dioxanone)
    6.
    发明授权
    Medical devices containing high inherent viscosity poly(p-dioxanone) 失效
    含有高特性粘度的聚（对二氧杂环己酮）

    公开(公告)号：US5611986A

    公开(公告)日：1997-03-18

    申请号：US270712

    申请日：1994-07-05

    申请人： Arindam Datta ,  Rohit Tandon ,  I-Jen Chen ,  Bethany A. Canterberry ,  Scott E. Fitzgerald

    发明人： Arindam Datta ,  Rohit Tandon ,  I-Jen Chen ,  Bethany A. Canterberry ,  Scott E. Fitzgerald

    IPC分类号： A61L17/00 ,  A61L17/12 ,  A61L31/06 ,  C08G63/06 ,  C08G63/664 ,  B29F1/06 ,  B29F1/08

    CPC分类号： C08G63/664 ,  A61L17/12 ,  A61L31/06 ,  Y10T428/252

    摘要： The present invention discloses polymers of poly(p-dioxanone having an inherent viscosity in the range of from 2.3 dL/g to about 8 dL/g, as determined at a concentration of 0.1 g/dL in hexafluoroisopropanol at 25.degree. C. This invention also describes improved surgical devices and filaments made from poly(p-dioxanone) with an inherent viscosity in the range of from 2.3 dL/g to about 8 dL/g, determined at a concentration of 0.1 g/dL in hexafluoroisopropanol at 25.degree. C. Additionally, disclosed are processes for manufacturing poly(p-dioxanone) with an inherent viscosity in the range of from 2.3 dL/g to about 8 dL/g, as determined at a concentration of 0.1 g/dL in hexafluoroisopropanol at 25.degree. C., as well as, processes for molding surgical articles and extruding surgical filaments from these polymers.

    摘要翻译： 本发明公开了在25℃下在六氟异丙醇中以0.1g / dL的浓度测定的特性粘度范围为2.3dL / g至约8dL / g的聚对苯二甲酸酮的聚合物。本发明 还描述了在25℃下在六氟异丙醇中以0.1g / dL的浓度测定的具有2.3dL / g至约8dL / g范围内的特性粘度的由聚对二恶烷酮制成的改进的手术装置和细丝 此外，公开了在25℃下在六氟异丙醇中以0.1g / dL的浓度测定的特性粘度为2.3dL / g至约8dL / g的聚（对二恶烷酮）的方法 以及用于模制外科用品并从这些聚合物挤压外科长丝的方法。