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公开(公告)号:US20250059237A1
公开(公告)日:2025-02-20
申请号:US18804679
申请日:2024-08-14
Applicant: Boston Scientific Scimed, Inc.
Inventor: Joseph Thomas Delaney, JR. , Rick Dorn , Yen-Hao Hsu , Cristian Parisi
Abstract: In various aspects, the present disclosure pertains to methods of forming an iodinated peptide compound that comprises: (a) forming a multifunctional precursor compound comprising (i) a residue of an amine-protected peptide that comprises two or more amino acid residues with primary-amine-containing side groups and (ii) a multifunctional moiety linked to the amine-protected peptide residue through an amide group or an ester group; (b) reacting the multifunctional precursor compound in an amide coupling reaction or an esterification coupling reaction with an iodinated compound to form an iodinated, amine-protected peptide compound comprising n iodinated moieties that are covalently attached to the amine-protected peptide residue through a residue of the multifunctional moiety; and (c) deprotecting the iodinated, amine-protected peptide compound to form the iodinated peptide compound.
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公开(公告)号:US20250057407A1
公开(公告)日:2025-02-20
申请号:US18938545
申请日:2024-11-06
Applicant: Boston Scientific Scimed, Inc.
Inventor: Christopher L. OSKIN
Abstract: A medical device may include an insertion portion longitudinally extending between a proximal end and a distal end. The insertion portion may define a channel extending therethrough. The medical device may further include a handle coupled to the proximal end of the insertion portion. The handle may further include an irrigation port in fluid communication with the channel and coupled to a source of irrigation fluid. Additionally, the handle may include an actuator and a pressurizer. Manipulation of the actuator may be configured to actuate the pressurizer to urge irrigation fluid distally through the channel.
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公开(公告)号:US12226793B2
公开(公告)日:2025-02-18
申请号:US18496982
申请日:2023-10-30
Applicant: Boston Scientific Scimed, Inc.
Inventor: Andrew Pic , Joseph King , Amanda Smith , Jessica Grimsby , John Favreau , Lauren Lydecker
Abstract: A device for fluidizing and delivering a powdered agent, including a canister extending longitudinally from a first to a second end and defining a space within which a powdered agent is received, an inlet coupleable to a gas source for supplying gas to the space to fluidize the powdered agent to create a fluidized mixture, an outlet via which the gas mixture is delivered to a target area, a tube extending from the outlet into the interior space, the tube including a slot extending through a wall thereof so that gas mixture is passable from the interior space through the outlet via the second end and the slot, and a door movably coupled to the tube so that the door is movable over the slot to control a size of the slot open to the interior space of the canister.
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公开(公告)号:US20250049556A1
公开(公告)日:2025-02-13
申请号:US18928829
申请日:2024-10-28
Applicant: Boston Scientific Scimed, Inc.
Inventor: Kenneth F. Binmoeller , Sieu T. Duong , Hanh Huu Duong , Thao Vi Nguyen
Abstract: A tissue lumen stent is provided with a body having an elongated tubular configuration and a foreshortened configuration. In the foreshortened configuration, downstream and upstream ends of the body expand radially into downstream and upstream flange structures, leaving a generally cylindrical saddle region therebetween. In some embodiments, the flange structures are non-symmetrical with respect to one another. Systems and methods of using the stents are also disclosed.
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公开(公告)号:US20250049420A1
公开(公告)日:2025-02-13
申请号:US18796486
申请日:2024-08-07
Applicant: Boston Scientific Scimed, Inc.
Inventor: Paul SMITH , Scott E. BRECHBIEL , Andrew James SCHAUBHUT , Narunn SUON , Tony SOUKALOPOULOS , Naomi GANNON
IPC: A61B10/02
Abstract: A cytology brush including a base wire having a distal end; at least one coiled loop; and a plurality of bristles. The coiled loop is configured to at least partially surround a portion of a guide wire such that the cytology brush is longitudinally movable along and adjacent to the guide wire.
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公开(公告)号:US12220103B2
公开(公告)日:2025-02-11
申请号:US18240562
申请日:2023-08-31
Applicant: Boston Scientific Scimed, Inc.
Inventor: John B. Golden , John O. McWeeney , Christopher A. Benning , Robert Castoldi , John F. Howard , Brian Intoccia , Gary Kappel , William L. Churchill
Abstract: Various apparatuses to attach a first medical device to a second medical device are described that allow the physician to grasp only a single device while the other device remains securely attached to the one being grasped. The apparatuses, once they are attached to the first medical device, are designed to be easily and quickly attached and detached to a second medical device, normally only requiring the use of one hand. Furthermore, the apparatuses oftentimes include a base that can easily couple and decouple from the portion that is attached to the second medical device so that if the need arises to separately use the second medical device, it can be decoupled from the first medical device without completely removing the apparatus from the second medical device.
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公开(公告)号:US20250040916A1
公开(公告)日:2025-02-06
申请号:US18787258
申请日:2024-07-29
Inventor: Deepak Kumar SHARMA , Sharath Kumar G , Paul SMITH , Scott E. BRECHBIEL
IPC: A61B10/02
Abstract: A cytology brush includes a shaft including a fluid lumen configured for passage of a fluid; a brush body including: a fixed element; and a moveable element with a radial outward surface and a plurality of bristles, wherein the bristles protrude externally from the radial outward surface. The moveable element is configured to receive the fluid through the fluid lumen to expand from an unexpanded configuration to an expanded configuration and in the unexpanded configuration of the moveable element, the bristles are in a retracted configuration and in the expanded configuration the bristles are in a deployed configuration.
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公开(公告)号:US20250040893A1
公开(公告)日:2025-02-06
申请号:US18788657
申请日:2024-07-30
Applicant: Boston Scientific Scimed, Inc.
Inventor: Michael McGOVERN
IPC: A61B5/00 , A61B1/00 , A61B5/0205 , G16H40/63
Abstract: A medical system includes a processing unit, a medical device electrically coupled to the processing unit, and an electronic assembly disposed at a distal portion of the insertion portion. The medical device includes an insertion portion configured to be inserted into a body lumen of a subject. The electronic assembly includes at least a first sensor, a second sensor, and a switch. The electronic assembly is electrically coupled to the processing unit. The switch is configured to switch between the first sensor and the second sensor based on an instruction of the processing unit.
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9.
公开(公告)号:US20250040791A1
公开(公告)日:2025-02-06
申请号:US18792676
申请日:2024-08-02
Applicant: Boston Scientific Scimed, Inc.
Inventor: Kurt Nicholas ROBAKIEWICZ , Christopher A. BENNING , Ryan V. WALES , Scott E. BRECHBIEL , John B. GOLDEN , Paul SMITH
Abstract: A medical system may include a fluid source, a fluid reservoir, and a valve. The valve may be coupled to the fluid source and the fluid reservoir so as to permit fluid flow between the fluid source and the fluid reservoir. The valve may include a first opening configured to receive a medical instrument. Upon insertion of the medical instrument into the first opening of the valve, the medical instrument may be lubricated with a fluid from the fluid source.
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公开(公告)号:US12214184B2
公开(公告)日:2025-02-04
申请号:US17114720
申请日:2020-12-08
Applicant: Boston Scientific Scimed, Inc.
Inventor: Joel B. Artmann , Bo Zhang , Eric A. Schilling , David I. Siegfried , Stephen M. Nelson
IPC: A61M60/873 , A61M60/178 , H02J7/00 , H02J50/10
Abstract: In an implanted medical device system, an internal controller, external power transmitter and methods for performing battery conditioning are disclosed. According to one aspect, an internal controller includes processing circuitry configured to cause conditioning of an internal battery of the internal controller responsive to a direction from an external power transmitter in radio communication with the internal controller.
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