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公开(公告)号：US08460214B2
公开(公告)日：2013-06-11
申请号：US12579267
申请日：2009-10-14
IPC分类号： A61M25/09 , A61M25/092
CPC分类号： A61M25/09033 , A61M25/09041 , A61M2025/09116 , A61M2205/0266
摘要： A vascular guidewire system includes a tubular member which at least partially encloses a core wire. A first or distal gripper is connected with a handle to grip a proximal end portion of the tubular member. A second or proximal gripper is disposed in the handle and grips a proximal end portion of the core wire. A first or distal motor is disposed in the handle and is operable to rotate the core wire relative to the outer tubular member. A second or proximal motor is disposed in the handle and is operable to move the first or distal motor longitudinally relative to the handle to thereby move the core wire longitudinally relative to the outer tubular member. The second or proximal motor is disposed in a coaxial relationship with the first or distal motor. Rotational and/or longitudinally directed forces may be manually applied to the handle to move the tubular member and core wire relative to a patient's body.
摘要翻译： 血管导丝系统包括至少部分地包围芯线的管状构件。 第一或远端夹持器与手柄连接以夹紧管状构件的近端部分。 第二或近端夹持器设置在手柄中并且夹持芯线的近端部分。 第一或远端马达设置在手柄中并且可操作以相对于外管状构件转动芯线。 第二或近端马达设置在手柄中并且可操作以相对于手柄纵向移动第一或远端马达，从而相对于外管状构件纵向移动芯线。 第二或近端电动机以与第一或远端电动机同轴的关系设置。 旋转和/或纵向力可以手动地施加到手柄以使管状构件和芯线相对于患者的身体移动。
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公开(公告)号：US08303503B2
公开(公告)日：2012-11-06
申请号：US11445679
申请日：2006-06-01
IPC分类号： A61B8/00
CPC分类号： A61B8/12 , A61B5/02007 , A61B5/7257 , A61B5/726 , A61B8/0833 , G06T7/0012 , G06T2207/30101
摘要： A system and method is provided for using backscattered data and known parameters to characterize vascular tissue. Specifically, in one embodiment of the present invention, an ultrasonic device is used to acquire RF backscattered data (i.e., IVUS data) from a blood vessel. The IVUS data is then transmitted to a computing device and used to create an IVUS image. The blood vessel is then cross-sectioned and used to identify its tissue type and to create a corresponding image (i.e., histology image). A region of interest (ROI), preferably corresponding to the identified tissue type, is then identified on the histology image. The computing device, or more particularly, a characterization application operating thereon, is then adapted to identify a corresponding region on the IVUS image. To accurately match the ROI, however, it may be necessary to warp or morph the histology image to substantially fit the contour of the IVUS image. After the corresponding region is identified, the IVUS data that corresponds to this region is identified. Signal processing is then performed and at least one parameter is identified. The identified parameter and the tissue type (e.g., characterization data) is stored in a database. In another embodiment of the present invention, the characterization application is adapted to receive IVUS data, determine parameters related thereto (either directly or indirectly), and use the parameters stored in the database to identify a tissue type or a characterization thereof.
摘要翻译： 提供了一种使用背散射数据和已知参数来表征血管组织的系统和方法。 具体地，在本发明的一个实施例中，使用超声波装置从血管获取RF背散射数据（即，IVUS数据）。 然后将IVUS数据传输到计算设备并用于创建IVUS图像。 然后将血管切片并用于识别其组织类型并产生相应的图像（即，组织学图像）。 然后在组织学图像上识别优选对应于所识别的组织类型的感兴趣区域（ROI）。 然后，计算设备，或更具体地，在其上操作的表征应用程序适用于识别IVUS图像上的对应区域。 然而，为了精确地匹配ROI，可能需要使组织学图像变形或变形以基本上适合IVUS图像的轮廓。 识别对应区域后，识别与该区域对应的IVUS数据。 然后执行信号处理，并且识别至少一个参数。 所识别的参数和组织类型（例如表征数据）被存储在数据库中。 在本发明的另一个实施例中，表征应用适于接收IVUS数据，确定与其相关的参数（直接或间接），并且使用存储在数据库中的参数来识别组织类型或其表征。
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公开(公告)号：US07978916B2
公开(公告)日：2011-07-12
申请号：US12102661
申请日：2008-04-14
CPC分类号： G06T7/0012 , A61B5/02007 , A61B8/12 , G06T7/12 , G06T2207/10132 , G06T2207/20101 , G06T2207/30101
摘要： A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. Specifically, in one embodiment of the present invention, an IVUS console is electrically connected to a computing device and adapted to acquire IVUS data. The IVUS data (or multiple sets thereof) is then provided to (or acquired by) the computing device. In one embodiment of the present invention, the computing device includes a plurality of applications operating thereon—i.e., a border-detection application, an extrapolation application, and an active-contour application. These applications are used to (i) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e., another IVUS image), (iii) identify a border on the second IVUS image, and (iv) adjust the border on the second IVUS image in accordance with at least one factor. In one embodiment of the present invention, the at least one factor is selected from a group consisting of gradient factor, continuity factor, and curvature factor.
摘要翻译： 提供了一种系统和方法，用于使用位于其上的第一血管图像，或更具体地多个控制点来识别第二血管图像上的边界。 本发明的实施例根据血管内超声（IVUS）装置和与其电连接的计算装置进行操作。 具体地，在本发明的一个实施例中，IVUS控制台电连接到计算设备并适于获取IVUS数据。 然后将IVUS数据（或其多组）提供给计算设备（或由其获取）。 在本发明的一个实施例中，计算设备包括在其上操作的多个应用，即边界检测应用，外推应用和主动轮廓应用。 这些应用用于（i）识别第一IVUS图像（即，任何IVUS图像）上的边界和控制点，（ii）将控制点外推到第二IVUS图像（即另一IVUS图像），（iii） 识别第二IVUS图像上的边界，以及（iv）根据至少一个因素调整第二IVUS图像上的边界。 在本发明的一个实施例中，至少一个因素选自由梯度因子，连续性因子和曲率因子组成的组。
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公开(公告)号：US07874990B2
公开(公告)日：2011-01-25
申请号：US10758477
申请日：2004-01-14
IPC分类号： A61B8/00
CPC分类号： A61B5/02007 , A61B5/726 , A61B8/12
摘要： A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter (including components attached thereto—e.g., IVUS console, transducer, etc.). Specifically, in accordance with a first embodiment of the present invention, a computing device is electrically connected to a catheter and used to acquire RF backscattered data from a vascular structure (e.g., a blood vessel, etc.). The backscattered ultrasound data is then used, together with an algorithm, to estimate the transfer function. The transfer function can then be used (at least in a preferred embodiment) to calculate response data for the vascular tissue (i.e., the tissue component of the backscattered ultrasound data). In a second embodiment of the present invention, an IVUS console is electrically connected to a catheter and a computing device and is used to acquire RF backscattered data from a vascular structure. The backscattered data is then transmitted to the computing device, where it is used to estimate the catheter's transfer function and to calculate response data for the vascular tissue. The response data and histology data are then used to characterize at least a portion of the vascular tissue (e.g., identify tissue type, etc.).
摘要翻译： 提供了一种系统和方法，用于使用从血管组织反向散射的超声数据来估计导管（包括与其连接的部件，例如，IVUS控制台，换能器等）的传递功能。 具体地，根据本发明的第一实施例，计算设备电连接到导管并用于从血管结构（例如，血管等）获取RF背散射数据。 然后将后向散射的超声数据与算法一起用于估计传递函数。 然后可以使用传递函数（至少在一个优选实施例中）来计算血管组织的反应数据（即背散射超声数据的组织分量）。 在本发明的第二实施例中，IVUS控制台电连接到导管和计算设备，并用于从血管结构获取RF背散射数据。 然后将背散射数据传输到计算设备，其中其用于估计导管的传递函数并计算血管组织的反应数据。 然后使用响应数据和组织学数据来表征血管组织的至少一部分（例如，识别组织类型等）。
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公开(公告)号：US08449465B2
公开(公告)日：2013-05-28
申请号：US11580342
申请日：2006-10-14
IPC分类号： A61B8/00
CPC分类号： A61B8/0891 , A61B5/02007 , A61B5/7203 , A61B5/726 , A61B8/0833 , A61B8/12 , A61B8/4461 , A61B8/4488 , A61B8/461 , A61B8/467 , A61B8/52 , A61B8/5238 , G01S7/5205 , G01S7/52087 , G01S15/8977 , G06F19/00
摘要： A system and method is provided for using ultrasound data backscattered from vascular tissue to estimate the transfer function of a catheter and/or substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. In one embodiment, a computing device and catheter acquire RF backscattered data from a vascular structure. The backscattered ultrasound data is then used to estimate at least one transfer function. The transfer function(s) can then be used to calculate response data for the vascular tissue. Another embodiment includes an IVUS console connected to a catheter and a computing device that acquires RF backscattered data from a vascular structure. Based on the backscattered data, the computing device estimates the catheter's transfer function and to calculate response data for the vascular tissue. The response data and histology data are then used to characterize at least a portion of the vascular tissue.
摘要翻译： 提供了一种用于使用从血管组织反向散射的超声数据来估计导管的传递功能和/或使血管数据的获取基本上同步到心跳数据的可识别部分的系统和方法。 在一个实施例中，计算装置和导管从血管结构获取RF背散射数据。 然后使用后向散射超声数据来估计至少一个传递函数。 然后可以使用传递函数来计算血管组织的反应数据。 另一个实施例包括连接到导管的IVUS控制台和从血管结构获取RF背散射数据的计算设备。 基于背散射数据，计算装置估计导管的传递函数并计算血管组织的反应数据。 然后使用响应数据和组织学数据来表征血管组织的至少一部分。
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公开(公告)号：US20130028497A1
公开(公告)日：2013-01-31
申请号：US13563299
申请日：2012-07-31
IPC分类号： G06K9/00
CPC分类号： G06T7/0012 , A61B5/02007 , A61B8/12 , G06T7/12 , G06T2207/10132 , G06T2207/20101 , G06T2207/30101
摘要： A system and method are provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. In one embodiment, the computing device includes a plurality of applications operating thereon that are used to (I) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e., another IVUS image), (iii) identify a border on the second IVUS image, and (iv) adjust the border on the second IVUS image in accordance with at least one factor.
摘要翻译： 提供了一种系统和方法，用于使用位于其上的第一血管图像，或更具体地多个控制点来识别第二血管图像上的边界。 本发明的实施例根据血管内超声（IVUS）装置和与其电连接的计算装置进行操作。 在一个实施例中，计算设备包括多个在其上操作的应用，其用于（I）识别第一IVUS图像（即，任何IVUS图像）上的边界和控制点，（ii）将控制点外推到第二IVUS IVUS图像（即另一IVUS图像），（iii）识别第二IVUS图像上的边界，以及（iv）根据至少一个因素调整第二IVUS图像上的边界。
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公开(公告)号：US07769470B1
公开(公告)日：2010-08-03
申请号：US11641860
申请日：2006-12-20
申请人： Ali Rezai , John Hall , Barry D. Kuban , Ken Baker
发明人： Ali Rezai , John Hall , Barry D. Kuban , Ken Baker
IPC分类号： A61N1/04
CPC分类号： A61N1/0529 , A61N1/0534
摘要： A device for modulating a volume of neural tissue comprising: a cannula having a proximal end, a distal end, and a lumen extending to at least the distal end, an actuator mechanism at least partially disposed in the lumen of the cannula; a plurality of leads having at least one electrode disposed thereon, the plurality of leads being coupled to the actuator mechanism to reciprocate between a retracted position wherein the plurality of leads are radially constrained within the lumen and an extended position; and a guide provided at the distal end of the cannula to deflect the plurality of leads radially outwardly into the neural tissue when the actuator mechanism is moved to the extended position.
摘要翻译： 一种用于调节神经组织的体积的装置，包括：套管，其具有近端，远端和至少延伸到所述远端的内腔，致动器机构至少部分地设置在所述套管的内腔中; 多个引线，其上设置有至少一个电极，所述多个引线联接到所述致动器机构以在缩回位置之间往复运动，在所述缩回位置，所述多个引线径向地限制在所述内腔内和延伸位置; 以及引导件，其设置在套管的远端处，以在致动器机构移动到伸出位置时将多个引线径向向外偏转进入神经组织。
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公开(公告)号：US07678064B2
公开(公告)日：2010-03-16
申请号：US11874571
申请日：2007-10-18
申请人： Barry D. Kuban
发明人： Barry D. Kuban
IPC分类号： A61B19/00
CPC分类号： A61B5/0053 , A61B5/4824 , A61B5/4827 , A61B2560/0223
摘要： An apparatus for helping to determine tactile sensitivity of a patient includes a housing and a probe supported by the housing and having a probe tip. The probe is adapted for selective longitudinal movement relative to the housing between a first probe position, wherein the probe tip is substantially extended from the housing, and a second probe position, wherein the probe tip is substantially retracted into the housing. A first biasing means is adapted to urge the probe toward the first probe position. A predetermined motive force is selectively exerted between the probe tip and the patient to move the probe from the first probe position to the second probe position. The motive force is indicative of tactile sensitivity of the patient. A method for helping to determine tactile sensitivity of a patient is also described.
摘要翻译： 用于帮助确定患者的触觉灵敏度的装置包括壳体和由壳体支撑并具有探针尖端的探针。 该探针适于在第一探针位置（其中探针尖端基本上从壳体延伸）和第二探针位置之间相对于壳体的选择性纵向移动，其中探针尖端基本上缩回到壳体中。 第一偏压装置适于将探针推向第一探针位置。 选择性地在探针尖端和患者之间施加预定的动力，以将探针从第一探针位置移动到第二探针位置。 动力表示患者的触觉敏感性。 还描述了帮助确定患者的触觉敏感性的方法。
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公开(公告)号：US20080287795A1
公开(公告)日：2008-11-20
申请号：US12102661
申请日：2008-04-14
IPC分类号： A61B8/12
CPC分类号： G06T7/0012 , A61B5/02007 , A61B8/12 , G06T7/12 , G06T2207/10132 , G06T2207/20101 , G06T2207/30101
摘要： A system and method is provided for using a first vascular image, or more particularly a plurality of control points located thereon, to identify a border on a second vascular image. Embodiments of the present invention operate in accordance with an intra-vascular ultrasound (IVUS) device and a computing device electrically connected thereto. Specifically, in one embodiment of the present invention, an-IVUS console is electrically connected to a computing device and adapted to acquire IVUS data. The IVUS data (or multiple sets thereof) is then provided to (or acquired by) the computing device. In one embodiment of the present invention, the computing device includes a plurality of applications operating thereon—i.e., a border-detection application, an extrapolation application, and an active-contour application. These applications are used to (i) identify a border and control points on a first IVUS image (i.e., any IVUS image), (ii) extrapolate the control points to a second IVUS image (i.e., another IVUS image), (iii) identify a border on the second IVUS image, and (iv) adjust the border on the second IVUS image in accordance with at least one factor. In one embodiment of the present invention, the at least one factor is selected from a group consisting of gradient factor, continuity factor, and curvature factor.
摘要翻译： 提供了一种系统和方法，用于使用位于其上的第一血管图像，或更具体地多个控制点来识别第二血管图像上的边界。 本发明的实施例根据血管内超声（IVUS）装置和与其电连接的计算装置进行操作。 具体来说，在本发明的一个实施例中，-IVUS控制台电连接到计算设备并适于获取IVUS数据。 然后将IVUS数据（或其多组）提供给计算设备（或由其获取）。 在本发明的一个实施例中，计算设备包括在其上操作的多个应用，即边界检测应用，外推应用和主动轮廓应用。 这些应用用于（i）识别第一IVUS图像（即，任何IVUS图像）上的边界和控制点，（ii）将控制点外推到第二IVUS图像（即另一IVUS图像），（iii） 识别第二IVUS图像上的边界，以及（iv）根据至少一个因素调整第二IVUS图像上的边界。 在本发明的一个实施例中，至少一个因素选自由梯度因子，连续性因子和曲率因子组成的组。
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公开(公告)号：US20110208017A1
公开(公告)日：2011-08-25
申请号：US13066659
申请日：2011-04-19
IPC分类号： A61B5/02
CPC分类号： A61B8/543 , A61B8/12 , A61B8/445 , G06T7/0012 , G06T2207/30101
摘要： A system and method is provided for substantially synchronizing the acquisition of blood-vessel data to an identifiable portion of heartbeat data. Specifically, a data-gathering device is adapted to acquire heartbeat data and blood-vessel data from a heart-monitoring device and a data-gathering probe, respectively. In a preferred embodiment of the present invention, the blood-vessel data is acquired during a cyclical portion of the heartbeat data. By identifying a cyclical (or commonly reoccurring) portion of the heartbeat data and acquiring blood-vessel data during this cyclical portion (or during an interval that substantially corresponds thereto), the blood vessel can be analyzed as if it were standing still—i.e., not expanding and relaxing. In one embodiment of the present invention, the heart-monitoring device includes an EKG device, the data-gathering device includes an intra-vascular ultrasound (IVUS) device and a computing device, and the data-gathering probe includes at least one transducer. In another embodiment of the present invention, the data-gathering system further includes a retraction device adapted to move the data-gathering probe though a blood vessel at a substantially steady speed.
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