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27 条记录 (耗时 0.042 秒)

    Method for treatment of constipation-predominant irritable bowel syndrome
    2.
    发明授权
    Method for treatment of constipation-predominant irritable bowel syndrome 有权
    治疗便秘型肠易激综合征的方法

    公开(公告)号：US08067041B2

    公开(公告)日：2011-11-29

    申请号：US12476590

    申请日：2009-06-02

    申请人： Barry D. Quart ,  David P. Rosenbaum

    发明人： Barry D. Quart ,  David P. Rosenbaum

    IPC分类号： A61K36/00 ,  A61K31/353

    CPC分类号： A61K36/47

    摘要： The present invention provides methods for treating constipation-predominant irritable bowel syndrome comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat constipation-predominant irritable bowel syndrome (c-IBS). Treatment of c-IBS includes the treatment of the constipation component of c-IBS as well as the pain and abdominal discomfort associated with c-IBS. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in an alternative embodiment also provides methods for treating alternating constipation-predominant/diarrhea-predominant irritable bowel syndrome.

    摘要翻译： 本发明提供了治疗便秘型肠易激综合征综合征的方法，其包括向有需要的患者施用足以治疗便秘型肠易激综合征（c-IBS）的来自巴豆种或Calophyllum物种的聚合原花青素组合物， 。 c-IBS的治疗包括治疗c-IBS的便秘成分以及与c-IBS相关的疼痛和腹部不适。 在一个实施方案中，聚合物原花青素化合物是疏水剂。 在替代实施方案中的本发明还提供了治疗交替便秘型/腹泻型肠易激综合征的方法。

    Method for treatment of constipation-predominant irritable bowel syndrome
    5.
    发明授权
    Method for treatment of constipation-predominant irritable bowel syndrome 有权
    治疗便秘型肠易激综合征的方法

    公开(公告)号：US09138450B2

    公开(公告)日：2015-09-22

    申请号：US13271624

    申请日：2011-10-12

    申请人： Barry D. Quart ,  David P. Rosenbaum

    发明人： Barry D. Quart ,  David P. Rosenbaum

    IPC分类号： A61K36/00 ,  A61K36/47

    CPC分类号： A61K36/47

    摘要： The present invention provides methods for treating constipation-predominant irritable bowel syndrome comprising administering to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat constipation-predominant irritable bowel syndrome (c-IBS). Treatment of c-IBS includes the treatment of the constipation component of c-IBS as well as the pain and abdominal discomfort associated with c-IBS. In one embodiment, the polymeric proanthocyanidin compound is crofelemer. The present invention in an alternative embodiment also provides methods for treating alternating constipation-predominant/diarrhea-predominant irritable bowel syndrome.

    摘要翻译： 本发明提供了治疗便秘型肠易激综合征综合征的方法，其包括向有需要的患者施用足以治疗便秘型肠易激综合征（c-IBS）的来自巴豆种或Calophyllum物种的聚合原花青素组合物， 。 c-IBS的治疗包括治疗c-IBS的便秘成分以及与c-IBS相关的疼痛和腹部不适。 在一个实施方案中，聚合物原花青素化合物是疏水剂。 在替代实施方案中的本发明还提供了治疗交替便秘型/腹泻型肠易激综合征的方法。

    Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer
    6.
    发明授权
    Compositions and methods for treating or preventing inflammatory bowel disease, familial adenomatous polyposis and colon cancer 有权
    用于治疗或预防炎症性肠病，家族性腺瘤性息肉病和结肠癌的组合物和方法

    公开(公告)号：US08852649B2

    公开(公告)日：2014-10-07

    申请号：US11741797

    申请日：2007-04-30

    申请人： Barry D. Quart

    发明人： Barry D. Quart

    IPC分类号： A61K36/00 ,  A61K36/38 ,  A61K36/47

    CPC分类号： A61K31/353 ,  A61K36/185 ,  A61K36/38 ,  A61K36/47

    摘要： Methods for treating colon cancer include administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat colon cancer, which composition inhibits COX-2. Methods for treating inflammation locally in the intestines comprise administering, to a patient in need thereof, a polymeric proanthocyanidin composition from a Croton species or Calophyllum species in an amount sufficient to treat inflammation. In one embodiment, the polymeric proanthocyanidin compound is crofelemer.

    摘要翻译： 用于治疗结肠癌的方法包括向有需要的患者施用足以治疗结肠癌的量的来自巴豆属物种或Calophyllum物种的聚合物原花青素组合物，该组合物抑制COX-2。 用于在肠部局部治疗炎症的方法包括以足以治疗炎症的量向来自巴豆物种或Calophyllum物种的有需要的患者施用聚合物原花青素组合物。 在一个实施方案中，聚合物原花青素化合物是疏水剂。