摘要:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要:
A multicore fiber includes cores located at vertexes of a polygonal ring and a cladding including sub medium regions and covering the cores. A refractive index of the cladding is lower than a refractive index of the cores and higher than a refractive index of the sub medium regions. The sub medium regions are arranged at positions to reduce a crosstalk between adjacent cores of the cores.
摘要:
There is provided a resin coated optical fiber, comprising at least: a glass optical fiber composed of a core and a clad for coating the core; a primary layer made of UV-curing resin in contact with the glass optical fiber; and a secondary layer made of the UV-curing resin disposed on an outer periphery of the primary layer, wherein the primary layer has a two-layer structure of an inner layer in contact with a surface of the clad, and an outer layer for coating the inner layer, wherein the UV-curing resin of the inner layer has Young's modulus of 0.9 MPa or more and 3.0 MPa or less at room temperature in a film state based on JIS standard K7113, and the UV-curing resin of the outer layer has Young's modulus of 0.1 MPa or more and 0.7 MPa or less at room temperature in a film state based on JIS standard K7113.
摘要:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要:
Chemical entities that modulate smooth muscle myosin and/or non-muscle myosin, pharmaceutical compositions and methods of treatment of diseases and conditions associated with smooth muscle myosin and/or non-muscle myosin are described.
摘要:
An optical fiber laser, according to the present invention, has an optical fiber including a core to which a rare earth element is added and a clad disposed around the core, and also has an excitation light source for emitting excitation light incident on a side of the optical fiber. The optical fiber has a corrugated shape on the outer circumference of the clad along the longitudinal direction thereof; and the optical fiber is wound in a spiral form and is bundled in such a way that adjacent sides of the clad are brought into contact with one another.
摘要:
The optical fiber 1 for an optical fiber laser is provided with a rare earth element doped core 2 doped with a rare earth element, and a cladding 3 formed at an outer periphery of the rare earth element doped core 2. In the optical fiber 1 for an optical fiber laser, the rare earth element doped core 2 is divided into a plurality of core regions 2a, 2b, . . . , 2n−1, 2n along a longitudinal direction of the optical fiber 1 and dopant concentrations of the rare earth element in respective core regions 2a, 2b, . . . , 2n−1, 2n are different from each other, in order to flatten a temperature distribution of the optical fiber 1 along the longitudinal direction.
摘要:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要:
Compounds useful for treating cellular proliferative diseases and disorders by modulating the activity of one or more mitotic kinesins are disclosed.
摘要:
A method of modulating KSP kinesin activity in vitro comprising contacting KSP kinesin with at least one chemical entity chosen from compounds represented by Formula I: and pharmaceutically acceptable salts thereof, where the variables are as defined further herein.