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1.2-(amino-substituted)-4-aryl pyrimidines and related compounds useful for treating inflammatory diseases 失效
标题翻译: 2-(氨基取代的)-4-芳基嘧啶和可用于治疗炎性疾病的相关化合物公开(公告)号:US08268822B2
公开(公告)日:2012-09-18
申请号:US12767139
申请日:2010-04-26
申请人: Paul E. Fleming , Zhan Shi , Brendan Shaowu Chen , Jane F. Schmidt , John C. Reader , Neal D. Hone , Jeffrey P. Ciavarri
发明人: Paul E. Fleming , Zhan Shi , Brendan Shaowu Chen , Jane F. Schmidt , John C. Reader , Neal D. Hone , Jeffrey P. Ciavarri
IPC分类号: C07D239/42 , C07D401/12 , A61K31/506
CPC分类号: C07D239/42 , C07D401/10 , C07D403/10
摘要: A heterocyclic inhibitor having the formula I, with the variables defined herein, which is useful for treating inflammatory and other physiological disorders in which PKC-theta isoform plays a role:
摘要翻译: 具有式I的杂环抑制剂,其具有本文定义的变量,其可用于治疗其中PKC-θ同种型起作用的炎性和其他生理障碍: