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1.发明授权公开(公告)号：US09723836B2
公开(公告)日：2017-08-08
申请号：US12622082
申请日：2009-11-19
Applicant: Bruce Spesard , Brian R. James , Guillaume Huchet , Raymond L. Cheek
Inventor： Bruce Spesard , Brian R. James , Guillaume Huchet , Raymond L. Cheek
CPC classification number: A01N37/38 , A01N37/40 , A01N39/02 , A01N39/04 , A01N43/68 , A01N43/80 , A01N25/00 , A01N43/40 , A01N2300/00
Abstract: Methods and compositions for synergistic pre-emergent and post-emergent weed control are disclosed. In particular, the present disclosure relates to an herbicidal composition comprising at least one pre-emergent herbicide and at least one post-emergent herbicide, wherein the pre-emergent herbicide and the post-emergent herbicide synergistically inhibit pre-emergent and post-emergent development of a weed. The disclosure further relates to herbicidal compositions comprising isoxaben, 2,4-D, mecoprop-P, and dicamba.
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公开(公告)号：US06252087B1
公开(公告)日：2001-06-26
申请号：US09123300
申请日：1998-07-28
Applicant: Cameron J. Koch , Alexander V. Kachur , Sydney M. Evans , Chyng-Yann Shiue , Ian R. Baird , Kirsten A. Skov , William R. Dolbier, Jr. , An-Rong Li , Brian R. James
Inventor： Cameron J. Koch , Alexander V. Kachur , Sydney M. Evans , Chyng-Yann Shiue , Ian R. Baird , Kirsten A. Skov , William R. Dolbier, Jr. , An-Rong Li , Brian R. James
IPC: C07D23391
CPC classification number: C07D233/91 , A61K49/001 , C07K16/44
Abstract: Nitroaromatic compounds and immunogenic conjugates comprising a novel nitroaromatic compound and a carrier protein are disclosed. The invention further presents monoclonal antibodies highly specific for the claimed nitroaromatic compounds, the compounds' protein conjugates, the compounds' reductive byproducts, and adducts formed between the compounds and mammalian hypoxic cell tissue proteins. The invention is further directed to methods for detecting tissue hypoxia using immunohistological techniques, non-invasive nuclear medicinal methods, or nuclear magnetic resonance. Diagnostic kits useful in practicing the methods of claimed invention are also provided.
Abstract translation: 公开了包含新型硝基芳族化合物和载体蛋白质的硝基芳族化合物和免疫原性缀合物。 本发明还提供对所要求保护的硝基芳族化合物，化合物的蛋白质缀合物，化合物的还原副产物以及化合物和哺乳动物缺氧细胞组织蛋白质之间形成的加合物高度特异性的单克隆抗体。 本发明还涉及使用免疫组织化学技术，非侵入性核医学方法或核磁共振来检测组织缺氧的方法。 还提供了可用于实践所要求保护的发明的方法的诊断试剂盒。
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公开(公告)号：US07496053B1
公开(公告)日：2009-02-24
申请号：US11287548
申请日：2005-11-23
Applicant: Aaron W. Seabaugh , Brian R. James , Joaquin Jares , Martin H. Rosalin
Inventor： Aaron W. Seabaugh , Brian R. James , Joaquin Jares , Martin H. Rosalin
IPC: H04L12/28
CPC classification number: H04M3/51 , G06F8/38 , H04M7/0024 , H04M2201/42 , H04M2201/54 , H04M2203/253
Abstract: A system and method for the rapid and visual web-based development of web-based customer service applications which render rich graphical user interfaces emulating the controls common to traditional desktop applications is disclosed. The rich user interface applications are comprised of scripting languages built with standard browser-based protocols and thus do not require the installation of any additional client-side or proprietary software applications. Not only is the user able to work on a rich user interface web application, but this application then allows the user to create, or develop, another web-based rich-thin-client application using visual programming tools.
Abstract translation: 公开了一种用于基于Web的客户服务应用程序的快速和可视化网络开发的系统和方法，其呈现模拟传统桌面应用程序通用控件的丰富图形用户界面。 丰富的用户界面应用程序由基于标准浏览器协议构建的脚本语言组成，因此不需要安装任何其他客户端或专有软件应用程序。 用户不仅可以在丰富的用户界面Web应用程序上工作，而且此应用程序允许用户使用可视化编程工具创建或开发另一个基于Web的富客户端应用程序。
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Patent Agency Ranking
公开(公告)号：US06855828B1
公开(公告)日：2005-02-15
申请号：US09648306
申请日：2000-08-25
Applicant: Cameron J. Koch , Alexander V. Kachur , Sydney M. Evans , Chyng-Yann Shiue , Ian R. Baird , Kirsten A. Skov , William R. Dolbier, Jr. , An-Rong Li , Brian R. James
Inventor： Cameron J. Koch , Alexander V. Kachur , Sydney M. Evans , Chyng-Yann Shiue , Ian R. Baird , Kirsten A. Skov , William R. Dolbier, Jr. , An-Rong Li , Brian R. James
IPC: A61K49/00 , C07D233/91 , C07K16/44
CPC classification number: C07D233/91 , A61K49/001 , C07K16/44 , Y10S436/905 , Y10T436/147777 , Y10T436/19
Abstract: Nitroaromatic compounds and immunogenic conjugates comprising a novel nitroaromatic compound and a carrier protein are disclosed. The invention further presents monoclonal antibodies highly specific for the claimed nitroaromatic compounds, the compounds' protein conjugates, the compounds' reductive byproducts, and adducts formed between the compounds and mammalian hypoxic cell tissue proteins. The invention is further directed to methods for detecting tissue hypoxia using immunohistological techniques, non-invasive nuclear medicinal methods, or nuclear magnetic resonance. Diagnostic kits useful in practicing the methods of claimed invention are also provided.
Abstract translation: 公开了包含新型硝基芳族化合物和载体蛋白质的硝基芳族化合物和免疫原性缀合物。 本发明还提供对所要求保护的硝基芳族化合物，化合物的蛋白质缀合物，化合物的还原副产物以及化合物和哺乳动物缺氧细胞组织蛋白质之间形成的加合物高度特异性的单克隆抗体。 本发明还涉及使用免疫组织化学技术，非侵入性核医学方法或核磁共振来检测组织缺氧的方法。 还提供了可用于实践所要求保护的发明的方法的诊断试剂盒。
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公开(公告)号：US4996361A
公开(公告)日：1991-02-26
申请号：US79625
申请日：1987-07-30
Applicant: William R. Cullen , Michael D. Fryzuk , Brian R. James , Guo-Jun Kang , James P. Kutney , Roberto Spogliarich , Ian S. Thorburn
Inventor： William R. Cullen , Michael D. Fryzuk , Brian R. James , Guo-Jun Kang , James P. Kutney , Roberto Spogliarich , Ian S. Thorburn
IPC: C07C209/44 , B01J31/24 , C07B31/00 , C07B43/04 , C07B53/00 , C07B61/00 , C07C67/00 , C07C209/00 , C07C209/52 , C07C213/00 , C07C213/02 , C07C217/08
CPC classification number: C07C209/52
Abstract: Asymmetric hydrogenation of prochiral N-arylketimines to give optically active secondary amines at a temperature from -40.degree. to 80.degree. C., under a hydrogen pressure of 10.sup.6 to 10.sup.8 Pa and with the addition of catalytic amounts of a rhodium compound of the formula III or IIIa ##STR1## in which X is 2 olefin ligands or a diene ligand, Y is a chiral diphosphine in which the secondary phosphine groups are linked by 2-4 C atoms and which, together with the Rh atom, forms a 5-membered, 6-membered or 7-membered ring, or Y is a chiral disphosphinite in which the phosphinite groups are linked via 2 C atoms and which, together with the Rh atom, forms a 7-membered ring, Z is Cl, Br or I and A.sup.- is the anion of an oxygen acid or complex acid.
Abstract translation: 在-40至80℃的温度下，在106至108Pa的氢气压力下加入催化量的式III的铑化合物，使前手性N-芳基酮亚胺不对称氢化得到光学活性仲胺 或其中X为2个烯属配体或二烯配体的IIIa [XRhYZ]（III）或[XRhY]（+）A（ - ）（IIIa），Y为手性二膦，其中仲膦基通过2- 4个C原子，并且其与Rh原子一起形成5元，6元或7元环，或Y是手性脱磷酸盐，其中所述膦基通过2个C原子连接，并且与 Rh原子形成7-元环，Z为Cl，Br或I，A-为氧酸或络合酸的阴离子。
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6.发明申请公开(公告)号：US20110118119A1
公开(公告)日：2011-05-19
申请号：US12622082
申请日：2009-11-19
Applicant: Bruce Spesard , Brian R. James , Guillaume Huchet , Raymond L. Cheek
Inventor： Bruce Spesard , Brian R. James , Guillaume Huchet , Raymond L. Cheek
CPC classification number: A01N37/38 , A01N37/40 , A01N39/02 , A01N39/04 , A01N43/68 , A01N43/80 , A01N25/00 , A01N43/40 , A01N2300/00
Abstract: Methods and compositions for synergistic pre-emergent and post-emergent weed control are disclosed. In particular, the present disclosure relates to an herbicidal composition comprising at least one pre-emergent herbicide and at least one post-emergent herbicide, wherein the pre-emergent herbicide and the post-emergent herbicide synergistically inhibit pre-emergent and post-emergent development of a weed. The disclosure further relates to herbicidal compositions comprising isoxaben, 2,4-D, mecoprop-P, and dicamba.
Abstract translation: 公开了用于协同出苗前和芽后杂草控制的方法和组合物。 特别地，本公开内容涉及包含至少一种芽前除草剂和至少一种芽后除草剂的除草组合物，其中芽前除草剂和芽后除草剂协同地抑制芽前和芽后发育 的杂草。 本公开还涉及除草组合物，其包含异恶草酮，2,4-D，甲基丙酸和麦草畏。
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7.发明授权公开(公告)号：US07285181B2
公开(公告)日：2007-10-23
申请号：US10770474
申请日：2004-02-04
Applicant: Thomas Qiuxiong Hu , Brian R. James , Dominggus Yawalata , Maria B. Ezhova
Inventor： Thomas Qiuxiong Hu , Brian R. James , Dominggus Yawalata , Maria B. Ezhova
CPC classification number: D21C9/1084 , D21C9/1047 , D21H21/32
Abstract: A method for the bleaching and brightness stabilization of lignocellulosic materials is described. The method involves the treatment of lignocellulosic materials, in particular, (a) wood pulps such as thermomechanical pulps (TMP) and chemithermomechanical pulps (CTMP), and (b) papers made from wood pulps, with a water-soluble phosphine or a phosphonium compound preferably containing at least one phosphorus hydroxyalkyl bond/linkage, for example a phosphorus hydroxymethyl bond/linkage (P—CH2OH). One example of such a water-soluble phosphine is the commercially available, tris(hydroxymethyl)phosphine (THP), P(CH2OH)3. One example of such a phosphonium compound is the commercially available, tetrakis(hydroxymethyl)phosphonium chloride (THPC), [P(CH2OH)4]Cl.
Abstract translation: 描述了用于木质纤维素材料的漂白和亮度稳定的方法。 该方法涉及木质纤维素材料的处理，特别是（a）木浆如热机械纸浆（TMP）和机械剪切纸浆（CTMP），和（b）由木浆制成的纸，其中含有水溶性膦或鏻 优选含有至少一个磷羟烷基键/键的化合物，例如磷羟甲基键/键（P-CH 2 OH）。 这种水溶性膦的一个实例是市售的三（羟甲基）膦（THP），P（CH 2 OH）3 3。 这种鏻化合物的一个实例是市售的氯化四（羟甲基）鏻（THPC），[P（CH 2 CH 2）4 Cl] Cl。
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公开(公告)号：US4693875A
公开(公告)日：1987-09-15
申请号：US900863
申请日：1986-08-27
Applicant: Brian R. James , Chung Li-Lee , Michael A. Lilga , David A. Nelson
Inventor： Brian R. James , Chung Li-Lee , Michael A. Lilga , David A. Nelson
CPC classification number: B01J31/4038 , B01J31/2404 , C01B17/05 , C01B3/04 , C07F15/0066 , B01J2231/70 , B01J2531/0216 , B01J2531/0219 , B01J2531/824 , B01J31/226 , Y02E60/364 , Y02P20/584
Abstract: A process of abstracting sulfur from H.sub.2 S and generating hydrogen is disclosed comprising dissolving Pd.sub.2 X.sub.2 (.mu.-dppm).sub.2 in a solvent and then introducing H.sub.2 S. The palladium complex abstracts sulfur, forming hydrogen and a (.mu.-S) complex. The (.mu.-S) complex is readily oxidizable to a (.mu.-SO.sub.2) adduct which spontaneously loses SO.sub.2 and regenerates the palladium complex.
Abstract translation: 公开了从H2S中提取硫并产生氢的方法，其包括将Pd 2 X 2（μ-Dppm）2溶解在溶剂中，然后引入H 2 S。 钯络合物提取硫，形成氢和（μ-S）络合物。 （μ-S）络合物易于氧化成自发失去SO 2并再生钯络合物的（μ--SO 2）加合物。
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