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公开(公告)号:US20100210682A1
公开(公告)日:2010-08-19
申请号:US12709125
申请日:2010-02-19
申请人: Connie R. Faltynek , Arthur R. Gomtsyan , Marie P. Honore , Michael F. Jarvis , Shailen K. Joshi , Michael E. Kort , Philip R. Kym , Torben R. Neelands , Regina M. Reilly , Carol S. Surowy
发明人: Connie R. Faltynek , Arthur R. Gomtsyan , Marie P. Honore , Michael F. Jarvis , Shailen K. Joshi , Michael E. Kort , Philip R. Kym , Torben R. Neelands , Regina M. Reilly , Carol S. Surowy
IPC分类号: A61K31/4725 , A61K31/416 , A61K31/444 , A61K31/421 , A61P29/00
CPC分类号: A61K31/416 , A61K31/421 , A61K31/444 , A61K31/4725
摘要: Disclosed herein are methods for increasing analgesic potency of TRPV1 antagonists, said methods comprise of repeated administration of the TRPV1 antagonists in a subject. Methods for treating or preventing pain by repeated administration of a TRPV1 antagonist are also discussed.
摘要翻译: 本文公开了增加TRPV1拮抗剂的止痛效力的方法,所述方法包括在受试者中重复施用TRPV1拮抗剂。 还讨论了通过重复施用TRPV1拮抗剂治疗或预防疼痛的方法。