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公开(公告)号:US07488833B2
公开(公告)日:2009-02-10
申请号:US10525821
申请日:2003-08-01
IPC分类号: C07D333/20 , C07C215/00
CPC分类号: C07D333/20 , C07C213/00 , C07F9/5027 , C07C215/30
摘要: A process for the enantioselective preparation of amino alcohols of formula I by enantioselective hydrogenation of amino ketones of the formula II in the presence of a non-racemic catalyst. The catalyst is a transition-metal complex in which the transition metal is complexed to a chiral diphosphine ligand.
摘要翻译: 通过在非外消旋催化剂存在下对式II的氨基酮进行对映选择性氢化来对映体选择性制备式I的氨基醇的方法。 催化剂是过渡金属络合物,其中过渡金属与手性二膦配体络合。