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公开(公告)号:US20100210036A1
公开(公告)日:2010-08-19
申请号:US12768729
申请日:2010-04-28
申请人: James Arnold , Dean R. Artis , Clarence H. Hurt , Prabha N. Ibrahim , Heike Krupka , Jack Lin , Michael V. Milburn , Weiru Wang , Chao Zhang
发明人: James Arnold , Dean R. Artis , Clarence H. Hurt , Prabha N. Ibrahim , Heike Krupka , Jack Lin , Michael V. Milburn , Weiru Wang , Chao Zhang
IPC分类号: G01N33/566 , C07D231/56 , C07D209/04 , C07D413/12 , C07D401/12
CPC分类号: C07D471/04 , C04B35/632 , C07D209/08 , C07D209/12 , C07D209/18 , C07D209/22 , C07D209/26 , C07D231/56 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D487/04
摘要: Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.
摘要翻译: 描述了对PPARs有活性的化合物,包括泛活性化合物。 还描述了用于开发或鉴定具有所需选择性分布的化合物的方法。