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公开(公告)号:US20100311767A1
公开(公告)日:2010-12-09
申请号:US12529331
申请日:2008-02-27
申请人: Volker Nimmrich , Stefan Barghorn , Ulrich Ebert , Heinz Hillen , Gerhard Gross , Andreas Draguhn , Claus Bruhl , Christine Grimm , Carsten Krantz
发明人: Volker Nimmrich , Stefan Barghorn , Ulrich Ebert , Heinz Hillen , Gerhard Gross , Andreas Draguhn , Claus Bruhl , Christine Grimm , Carsten Krantz
IPC分类号: A61K31/52 , A61K31/519 , A61K31/137 , A61P3/00 , A61P25/28 , A61P25/00
CPC分类号: A61K31/015 , A61K31/05 , A61K31/519 , A61K39/3955
摘要: The present invention relates to a method for the treatment of an amyloidosis such as Alzheimer's disease in a subject in need thereof, characterized in that it comprises administering an agonist of the P/Q type voltage-gated presynaptic calcium channel to said subject.
摘要翻译: 本发明涉及在有需要的受试者中治疗淀粉样变性如阿尔茨海默氏病的方法,其特征在于其包括向所述受试者施用P / Q型电压门控突触前钙通道的激动剂。
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公开(公告)号:US08895004B2
公开(公告)日:2014-11-25
申请号:US12529467
申请日:2008-02-27
申请人: Volker Nimmrich , Stefan Barghorn , Ulrich Ebert , Heinz Hillen , Gerhard Gross , Andreas Draguhn , Claus Bruhl , Christine Grimm , Carsten Krantz
发明人: Volker Nimmrich , Stefan Barghorn , Ulrich Ebert , Heinz Hillen , Gerhard Gross , Andreas Draguhn , Claus Bruhl , Christine Grimm , Carsten Krantz
IPC分类号: A61K39/395 , A61K31/015 , A61K31/05 , A61K31/519
CPC分类号: A61K31/015 , A61K31/05 , A61K31/519 , A61K39/3955
摘要: The present invention relates to a method for the treatment of an amyloidosis such as Alzheimer's disease in a subject in need thereof, characterized in that it comprises administering an inhibitor of the interaction between Aβ globulomer and the P/Q type voltage-gated presynaptic calcium channel to said subject.
摘要翻译: 本发明涉及在有需要的受试者中治疗淀粉样变性如阿尔茨海默病的方法,其特征在于其包括施用A&Bgr之间相互作用的抑制剂; 球聚体和P / Q型电压门控突触前钙通道。
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