QUILTED IMPLANTABLE GRAFT
    2.
    发明申请

    公开(公告)号:US20220296351A1

    公开(公告)日:2022-09-22

    申请号:US17833193

    申请日:2022-06-06

    摘要: Described are embodiments of a multilaminate or multiple layer implantable surgical graft with an illustrative graft comprising a remodelable collagenous sheet material, the graft including one or more interweaving members to stitch together the graft to help prevent the layers from delaminating or separating during handling and the initial stages of remodeling. The interweaving members may comprise lines of suture, thread, individual stitches, strips of material, etc. that are woven through the layers of biomaterial in a desired pattern. In one embodiment, the interweaving members comprise a pharmacologically active substance, such as a drug, growth factors, etc. to elicit a desired biological response in the host tissue. In another embodiment, the graft further comprises a reinforcing material, such as a synthetic mesh, within the layers of remodelable biomaterial and stitched together by one or more interweaving members.

    FIBRIN AND/OR DIALDEHYDE STARCH HYDROLYSATE MATERIALS, AND PREPARATION AND USE THEREOF

    公开(公告)号:US20190117825A1

    公开(公告)日:2019-04-25

    申请号:US16156340

    申请日:2018-10-10

    摘要: Various compositions of matter, methods of making compositions of matter, and methods of using compositions of matter, e.g. for inducing hemostasis, are disclosed. In some embodiments, a starting fibrin material is subjected to controlled hydrolysis, desirably base-catalyzed, to prepare a fibrin hydrolysate material with increased water sorption capacity. Such fibrin hydrolysate materials, alone or combined with one or more additional substances, can be used in the preparation of hemostasis promoting foams, powders or gels. In some embodiments, a starting dialdehyde starch material is subjected to controlled hydrolysis to prepare a dialdehyde starch hydrolysate material. Such dialdehyde starch hydrolysate materials, alone or combined with one or more additional substances, in some cases combined with a fibrin hydrolysate material, can be used in the preparation of hemostasis promoting foams, powders or gels.

    DEVICES AND METHODS USEFUL FOR SEALING BODILY OPENINGS
    10.
    发明申请
    DEVICES AND METHODS USEFUL FOR SEALING BODILY OPENINGS 审中-公开
    用于密封裸露开口的装置和方法

    公开(公告)号:US20160262737A1

    公开(公告)日:2016-09-15

    申请号:US15062749

    申请日:2016-03-07

    IPC分类号: A61B17/00

    摘要: Among other things, there are disclosed apparatuses and methods for medically sealing an opening in a vessel or wall. For example, in medical applications, a delivery tube is provided for insertion through a sheath into a vessel (e.g. a blood vessel). A dome-shaped seal fixed to a filament, an absorbent and/or compressible buffer, and a locking member are provided in the delivery tube. The delivery tube is configured so that it can be inserted into the vessel through a sheath. Tension is maintained on the filament to hold the seal against the tube or sheath. The sheath is pulled out, which pulls out the tube at the same time, leaving the seal over the opening in the vessel wall. The locking member compresses the buffer against the outside of the vessel and with the filament holds the seal in place against the inside of a vessel.

    摘要翻译: 除此之外,还公开了用于医​​疗密封容器或壁中的开口的装置和方法。 例如,在医疗应用中,提供输送管用于通过护套插入血管(例如血管)中。 固定在细丝上的圆顶形密封件,吸收性和/或可压缩缓冲器以及锁定构件设置在输送管中。 输送管被构造成使得其可以通过护套插入到容器中。 在灯丝上保持张力以将密封件保持在管或鞘上。 护套被拉出,同时拉出管子,将密封件留在血管壁的开口处。 锁定构件将缓冲器压靠在容器的外部,并且灯丝将密封件保持在与容器内部的适当位置。