-
公开(公告)号:US20110144069A1
公开(公告)日:2011-06-16
申请号:US11873356
申请日:2007-10-16
CPC分类号: C07J53/00 , C07D213/40 , C07D213/56 , C07D213/78 , C07D213/89 , C07D215/26 , C07D215/42 , C07D333/40
摘要: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
摘要翻译: 本发明涉及可用于治疗病毒感染的化合物,药物组合物和方法。
-
公开(公告)号:US20090105203A1
公开(公告)日:2009-04-23
申请号:US11873342
申请日:2007-10-16
IPC分类号: A61K31/56 , C07J53/00 , A61P35/00 , A61P31/18 , C07D305/08 , C07D213/56
CPC分类号: C07J53/00 , C07D213/40 , C07D213/56 , C07D213/78 , C07D213/89 , C07D215/26 , C07D215/42 , C07D333/40
摘要: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
摘要翻译: 本发明涉及可用于治疗病毒感染的化合物,药物组合物和方法。
-
公开(公告)号:US20120122840A1
公开(公告)日:2012-05-17
申请号:US13243876
申请日:2011-09-23
申请人: Dange Vijay Kumar , Ian A. McAlexander , Matthew Gregory Bursavich , Christophe Hoarau , Paul M. Slattum , David A. Gerrish , Jeffrey W. Lockman , Weston R. Judd , Michael Saunders , Daniel P. Parker , Daniel Feodore Zigar , In Chul Kim , J. Adam Willardsen , Kraig M. Yager , Mark D. Shenderovich , Brandi L. Williams , Keith D. Tardif
发明人: Dange Vijay Kumar , Ian A. McAlexander , Matthew Gregory Bursavich , Christophe Hoarau , Paul M. Slattum , David A. Gerrish , Jeffrey W. Lockman , Weston R. Judd , Michael Saunders , Daniel P. Parker , Daniel Feodore Zigar , In Chul Kim , J. Adam Willardsen , Kraig M. Yager , Mark D. Shenderovich , Brandi L. Williams , Keith D. Tardif
IPC分类号: A61K31/541 , C07D473/32 , G01N33/567 , A61K31/5377 , A61P35/00 , C07D473/16 , A61K31/52
CPC分类号: C07D487/04 , C07D519/00
摘要: The invention relates to compounds, pharmaceutical compositions, and uses thereof, including therapeutic uses thereof, such as methods useful for treating cancer.
摘要翻译: 本发明涉及化合物,药物组合物及其用途,包括其治疗用途,例如可用于治疗癌症的方法。
-
公开(公告)号:US20110207939A1
公开(公告)日:2011-08-25
申请号:US13100058
申请日:2011-05-03
申请人: Daniel A. Dickman , Dange Vijay Kumar , Colin O'Bryan , Roopa Rai , William Dvorak Shrader , Kieron Wesson
发明人: Daniel A. Dickman , Dange Vijay Kumar , Colin O'Bryan , Roopa Rai , William Dvorak Shrader , Kieron Wesson
IPC分类号: C07D235/12 , C07C69/76
CPC分类号: C07D235/18
摘要: The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.
摘要翻译: 本发明涉及因子VIIa,IXa,Xa,XIa,特别是因子VIIa的新型抑制剂,包含这些抑制剂的药物组合物,以及使用这些抑制剂治疗或预防血栓栓塞性疾病,癌症或类风湿性关节炎的方法。 还公开了制备这些抑制剂的方法。
-
公开(公告)号:US20080207573A1
公开(公告)日:2008-08-28
申请号:US12116864
申请日:2008-05-07
CPC分类号: C07J53/00 , C07D213/40 , C07D213/56 , C07D213/78 , C07D213/89 , C07D215/26 , C07D215/42 , C07D333/40
摘要: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
摘要翻译: 本发明涉及可用于治疗病毒感染的化合物,药物组合物和方法。
-
公开(公告)号:US20100240630A1
公开(公告)日:2010-09-23
申请号:US12794300
申请日:2010-06-04
CPC分类号: C07J63/008
摘要: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
摘要翻译: 本发明涉及可用于治疗病毒感染的化合物,药物组合物和方法。
-
公开(公告)号:US08415328B2
公开(公告)日:2013-04-09
申请号:US13100058
申请日:2011-05-03
申请人: Daniel A. Dickman , Dange Vijay Kumar , Colin O'Bryan , Roopa Rai , William Dvorak Shrader , Kieron Wesson
发明人: Daniel A. Dickman , Dange Vijay Kumar , Colin O'Bryan , Roopa Rai , William Dvorak Shrader , Kieron Wesson
CPC分类号: C07D235/18
摘要: The present invention relates to novel inhibitors of Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.
-
公开(公告)号:US20090275583A1
公开(公告)日:2009-11-05
申请号:US12422767
申请日:2009-04-13
申请人: Kraig Yager , In Chul Kim , Michael Saunders , David Gerrish , Dange Vijay Kumar , Mark B. Anderson
发明人: Kraig Yager , In Chul Kim , Michael Saunders , David Gerrish , Dange Vijay Kumar , Mark B. Anderson
IPC分类号: A61K31/5375 , C07D265/30 , A61P31/18
CPC分类号: C07J63/008
摘要: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
摘要翻译: 本发明涉及可用于治疗病毒感染的化合物,药物组合物和方法。
-
公开(公告)号:US20090149429A1
公开(公告)日:2009-06-11
申请号:US11993519
申请日:2006-06-22
申请人: Esther Arranz Plaza , Kraig M. Yager , David Allen Gerrish , Mark B. Anderson , In Chul Kim , Dange Vijay Kumar
发明人: Esther Arranz Plaza , Kraig M. Yager , David Allen Gerrish , Mark B. Anderson , In Chul Kim , Dange Vijay Kumar
CPC分类号: C07J63/008
摘要: The invention relates to compounds, pharmaceutical compositions and methods useful for treating viral infection.
摘要翻译: 本发明涉及可用于治疗病毒感染的化合物,药物组合物和方法。
-
公开(公告)号:US20080275250A1
公开(公告)日:2008-11-06
申请号:US11597335
申请日:2005-06-02
申请人: Daniel A. Dickman , Dange Vijay Kumar , Colin O'Bryan , Roopa Rai , William Dvorak Shrader , Kieron Wesson
发明人: Daniel A. Dickman , Dange Vijay Kumar , Colin O'Bryan , Roopa Rai , William Dvorak Shrader , Kieron Wesson
IPC分类号: C07D235/18
CPC分类号: C07D235/18
摘要: The present invention relates to novel inhibitors or Factors VIIa, IXa, Xa, XIa, in particular Factor VIIa, pharmaceutical compositions comprising these inhibitors, and methods for using these inhibitors for treating or preventing thromboembolic disorders, cancer or rheumatoid arthritis. Processes for preparing these inhibitors are also disclosed.
摘要翻译: 本发明涉及新的抑制剂或因子VIIa,IXa,Xa,XIa,特别是因子VIIa,包含这些抑制剂的药物组合物,以及使用这些抑制剂治疗或预防血栓栓塞性疾病,癌症或类风湿性关节炎的方法。 还公开了制备这些抑制剂的方法。
-
-
-
-
-
-
-
-
-