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    Servo control circuit for detecting analytes via nanoparticle-labeled substances with electromagnetic read-write heads
    4.
    发明授权
    Servo control circuit for detecting analytes via nanoparticle-labeled substances with electromagnetic read-write heads 有权
    用于通过具有电磁读写头的纳米颗粒标记物质检测分析物的伺服控制电路

    公开(公告)号：US08694280B2

    公开(公告)日：2014-04-08

    申请号：US12888403

    申请日：2010-09-22

    Applicant: Tara L. Awezec ,  Dylan Joseph Boday ,  Stephen Leonard Schwartz ,  Anna W. Topol ,  Daniel James Winarski

    Inventor： Tara L. Awezec ,  Dylan Joseph Boday ,  Stephen Leonard Schwartz ,  Anna W. Topol ,  Daniel James Winarski

    IPC: G01C9/00

    CPC classification number: G01N33/54346 ,  B82Y15/00 ,  G01N33/54326 ,  G01N33/54333

    Abstract: A circuit for controlling an electromagnetic head module to detect antigens on a biosample track comprising a processor for receiving position-error-servo signal from the PES read sensor, a write head for magnetizing nanoparticles attached to antigens, and a read sensor for detecting the nanoparticle-labeled antigens. The circuit may further comprise an X-axis actuator for controlling the head module in the direction perpendicular to the track and an Y-axis actuator coupled to the head module and the X-axis actuator for controlling the head module in the direction of the track. Target antigens are attached to the biosample track and nanoparticles via antibodies.

    Abstract translation: 一种用于控制电磁头模块以检测生物样本轨道上的抗原的电路，包括用于从PES读取传感器接收位置误差伺服信号的处理器，用于磁化附着于抗原的纳米颗粒的写入头和用于检测纳米颗粒的读取传感器 标记的抗原。 电路还可以包括用于在垂直于轨道的方向上控制头模块的X轴致动器，以及耦合到头模块的Y轴致动器和用于在轨道方向上控制头模块的X轴致动器 。 靶抗原通过抗体连接到生物样品轨道和纳米颗粒上。

    Power-up of device via optical serial interface
    5.
    发明授权
    Power-up of device via optical serial interface 有权
    通过光串行接口上​​电设备

    公开(公告)号：US08542991B2

    公开(公告)日：2013-09-24

    申请号：US13453654

    申请日：2012-04-23

    Applicant: Louie Arthur Dickens ,  Timothy A Johnson ,  Craig Anthony Klein ,  Gregg Steven Lucas ,  Daniel James Winarski

    Inventor： Louie Arthur Dickens ,  Timothy A Johnson ,  Craig Anthony Klein ,  Gregg Steven Lucas ,  Daniel James Winarski

    IPC: H04B10/08 ,  H04B17/00 ,  H04B10/00 ,  H04J14/00

    CPC classification number: H04B10/40

    Abstract: An optical communication serial interface is employed to power up a device from a powered down state to a powered on state. An optical receiver element receives serial optical signals transmitted by at least one optical fiber and converts the received serial optical signals to electrical signals. A low level reception converter detects and decodes the electrical signals to provide data and control words from detected and decoded normal electrical signals for a high level command processor. A power supply maintains low level power to at least the optical receiver element and the low level reception converter of the optical communication serial interface while the device is in the powered down state. The low level reception converter detects a particular abnormal sequence of electrical signals; and in response to detecting the particular abnormal sequence of electrical signals, asserts a control signal to power up the device controllable power supply.

    Abstract translation: 采用光通信串行接口将设备从掉电状态加电到上电状态。 光接收器元件接收由至少一个光纤传输的串行光信号，并将接收到的串行光信号转换为电信号。 低电平接收转换器检测并解码电信号，以提供来自用于高级命令处理器的检测和解码的正常电信号的数据和控制字。 当设备处于掉电状态时，电源至少保持光接收器元件和光通信串行接口的低电平接收转换器的低电平功率。 低电平接收转换器检测电信号的特定异常序列; 并且响应于检测到电信号的特定异常序列，断言控制信号以使设备可控电源上电。

    'Method for Calibrating Read Sensors of Electromagnetic Read-Write Heads'
    8.
    发明申请
    'Method for Calibrating Read Sensors of Electromagnetic Read-Write Heads' 有权
    “电磁读写头读取传感器校准方法”

    公开(公告)号：US20120283976A1

    公开(公告)日：2012-11-08

    申请号：US13099360

    申请日：2011-05-03

    Applicant: David Berman ,  Dylan Joseph Boday ,  Icko E.T. Iben ,  Wayne Isami Imaino ,  Stephen Leonard Schwartz ,  Anna Wanda Topol ,  Daniel James Winarski

    Inventor： David Berman ,  Dylan Joseph Boday ,  Icko E.T. Iben ,  Wayne Isami Imaino ,  Stephen Leonard Schwartz ,  Anna Wanda Topol ,  Daniel James Winarski

    IPC: G06F19/00

    CPC classification number: G01R35/00 ,  G01N27/04 ,  G01N27/72 ,  G01N33/53 ,  G01R33/0035 ,  G01R33/1207

    Abstract: Described are embodiments to ensure that the equipment utilized to detect antigens is reliable and accurate. If it is determined that a read sensor is degraded a method of calibrating a read sensor of a read head is described. In one embodiment, a method of calibrating a magnetic read sensor includes measuring a first resistance of the magnetic read sensor upon an application of a forward bias current to the magnetic read sensor and measuring a second resistance of the magnetic read sensor upon an application of a reverse bias current to the magnetic read sensor. A calibration constant is determined based on at least the first measured resistance and the second measured resistance. In one embodiment the method further includes storing the determined calibration constant for the magnetic read sensor in memory. Further, in one embodiment the head module having the magnetic read sensor is swept over at least one nanoparticle to obtain a read response of the magnetic read sensor to the nanoparticle. The read response from the magnetic read sensor of the at least one nanoparticle is adjusted based on the determined calibration constant. Calibration of each individual read sensor allows for uniform read responses from each of the read sensors on a read head, and prevents unreliable an inaccurate detection of analytes due to sensor degradation.

    Abstract translation: 描述了确保用于检测抗原的设备是可靠和准确的实施方案。 如果确定读取传感器劣化，则描述校准读取头的读取传感器的方法。 在一个实施例中，一种校准磁性读取传感器的方法包括：在向磁性读取传感器施加正向偏置电流时测量磁性读取传感器的第一个电阻，并测量磁性读取传感器的应用时的第二个电阻 反向偏置电流到磁性读取传感器。 基于至少第一测量电阻和第二测量电阻来确定校准常数。 在一个实施例中，该方法还包括将所确定的磁读取传感器的校准常数存储在存储器中。 此外，在一个实施例中，具有磁读取传感器的头模块扫过至少一个纳米颗粒，以获得磁读取传感器对纳米颗粒的读取响应。 基于所确定的校准常数来调整来自至少一个纳米颗粒的磁读取传感器的读取响应。 每个单独的读取传感器的校准允许来自读取头上的每个读取传感器的均匀的读取响应，并且防止由于传感器劣化而导致的分析物不可靠的检测不可靠。

    Convolution-encoded RAID with trellis-decode-rebuild
    9.
    发明授权
    Convolution-encoded RAID with trellis-decode-rebuild 有权
    卷积编码的RAID与格状解码重建

    公开(公告)号：US08245113B2

    公开(公告)日：2012-08-14

    申请号：US12115455

    申请日：2008-05-05

    Applicant: Daniel James Winarski ,  Craig A. Klein ,  Nils Haustein

    Inventor： Daniel James Winarski ,  Craig A. Klein ,  Nils Haustein

    IPC: G11C29/00

    CPC classification number: G06F11/1088

    Abstract: A Redundant Array of Independent Devices uses convolution encoding to provide redundancy of the striped data written to the devices. No parity is utilized in the convolution encoding process. Trellis decoding is used for both reading the data from the RAID and for rebuilding missing encoded data from one or more failed devices, based on a minimal, and preferably zero, Hamming distance for selecting the connected path through the trellis diagram.

    Abstract translation: 独立设备的冗余阵列使用卷积编码来提供写入设备的条带数据的冗余。 在卷积编码过程中没有使用奇偶校验。 基于用于选择通过网格图的连接路径的最小且优选为零的汉明距离，网格解码用于从RAID读取数据和从一个或多个故障设备重建丢失的编码数据。

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