公开(公告)号：US10426701B2

公开(公告)日：2019-10-01

申请号：US15410762

申请日：2017-01-19

申请人： Daniel Py

发明人： Daniel Py

IPC分类号： A61J1/20 ,  A61M5/162 ,  A61M39/10 ,  A61M39/18 ,  A61M39/26

摘要： Connector assembly including a piercing member having a flow port therein attached to a first piece, with the piercing member slidingly receivable within a second piece, wherein the piercing member and the second pierce are movable relative to each other between a first position where the second pieces closes the flow port and a second position where the flow port is open. The first piece contains a locking mechanism that lockingly engages with a device when connected thereto, preventing subsequent disconnection of first piece and the device. Upon initial connection of the first piece to the device, the second piece is moved from the first position to the second position.

公开(公告)号：US09737435B2

公开(公告)日：2017-08-22

申请号：US13745721

申请日：2013-01-18

申请人： Daniel Py

发明人： Daniel Py

IPC分类号： A61F9/00 ,  B23P15/00 ,  B05B11/00 ,  B65D83/00

CPC分类号： A61F9/0008 ,  B05B11/0056 ,  B05B11/0062 ,  B05B11/0067 ,  B05B11/007 ,  B05B11/0097 ,  B23P15/001 ,  B65D83/0022 ,  Y10T29/49412

摘要： A device has a first part with a valve seat and storage chamber, and a second part with a flexible valve cover and actuator. The storage chamber may be formed from a pre-form blow-molded into a flexible pouch defining a variable-volume storage chamber. The flexible valve cover and valve seat form a normally closed valve seam therebetween. The valve cover is movable in response to fluid at an inlet to the seam exceeding a valve opening pressure of the one-way valve between (i) a normally closed position with valve cover and valve seat in contact with each other and defining the normally closed seam, and (ii) a second position with at least a portion of the valve cover spaced away from the valve seat to allow the fluid to pass through the seam. The one-way valve may have anti-spritz features for using the device to dispense a substance, such as to the eye. The device may contain prostaglandins without the device material absorbing the prostaglandins material and/or without the material being adsorbed into the drug.

公开(公告)号：US09725228B2

公开(公告)日：2017-08-08

申请号：US13572145

申请日：2012-08-10

申请人： Daniel Py ,  Joseph M. Ting

发明人： Daniel Py ,  Joseph M. Ting

IPC分类号： B65D37/00 ,  B65D83/00 ,  A61F9/00 ,  B05B11/00 ,  B65D81/24

CPC分类号： B65D83/0055 ,  A61F9/0008 ,  B05B11/00412 ,  B05B11/0072 ,  B05B11/0097 ,  B05B11/3004 ,  B05B11/3074 ,  B05B11/3077 ,  B05B11/3092 ,  B05B11/3094 ,  B65D81/245

摘要： A dispenser for dispensing a fluid includes a rigid vial that has a main fluid chamber containing a fluid, and a pump assembly that is in fluid communication with the main fluid chamber and is configured to dispense a predetermined quantity of fluid from the main fluid chamber. A flexible bladder is provided which is located within the main fluid chamber and is configured to expand to fill the ullage created within the main fluid chamber during dispensing of fluid by the pump assembly. The resilient bladder tends to force itself outwardly toward the rigid vial and, in turn, increases the pressure within the main fluid chamber in comparison to the interior of the bladder to thereby prevent the ingress of air or vapors through the bladder or otherwise into the main fluid chamber.

公开(公告)号：US20170190456A1

公开(公告)日：2017-07-06

申请号：US15438231

申请日：2017-02-21

申请人： Daniel Py

发明人： Daniel Py

IPC分类号： B65D1/02 ,  B65D47/36 ,  B05B11/00 ,  B65B7/16 ,  B65B51/22 ,  A61J1/14 ,  B65D55/08 ,  B65B3/04

CPC分类号： B65D1/0215 ,  A61J1/05 ,  A61J1/1406 ,  A61J1/1412 ,  B05B11/00412 ,  B05B11/3028 ,  B29C48/0011 ,  B29C48/12 ,  B29C49/04 ,  B29C49/22 ,  B29C65/665 ,  B29C66/7371 ,  B29C2791/001 ,  B29C2793/0027 ,  B29K2101/12 ,  B29L2031/565 ,  B65B3/04 ,  B65B7/16 ,  B65B51/22 ,  B65D1/0223 ,  B65D1/0276 ,  B65D1/0284 ,  B65D47/36 ,  B65D55/0818 ,  B65D77/06 ,  B65D2501/0036 ,  B65D2501/0063 ,  B65D2501/0072 ,  B67C2003/227

摘要： A device that includes a first portion including a first polymer, a second portion including a second polymer, and a third portion defining a third polymer. The second polymer is substantially not bondable to the first polymer, and the third polymer is bondable to the first polymer and fixedly secures the first portion to the second portion. A device that includes a body and a closure and including and a first polymer, a second polymer and a third polymer, wherein the first polymer is bondable with the second polymer, and the third polymer is substantially not bondable to the first polymer.

公开(公告)号：US09211983B2

公开(公告)日：2015-12-15

申请号：US13847277

申请日：2013-03-19

申请人： Daniel Py

发明人： Daniel Py

IPC分类号： B65D35/56 ,  B65D47/24 ,  B65D23/02 ,  B65D47/32 ,  B05B11/00 ,  B29C47/00 ,  B29C47/06 ,  B29C49/04 ,  B29L9/00 ,  B29L31/00

CPC分类号： B65D47/24 ,  B05B11/3028 ,  B29C47/0021 ,  B29C47/0023 ,  B29C47/0026 ,  B29C47/065 ,  B29C47/068 ,  B29C49/04 ,  B29L2009/00 ,  B29L2031/7158 ,  B65D23/02 ,  B65D47/205 ,  B65D47/32

摘要： A device comprises a first portion including a first polymer, and a second portion that is relatively flexible in comparison to the first portion and includes a second polymer that is substantially not bondable to the first polymer. A chamber of the device is hermetically sealable with respect to ambient atmosphere and is defined by (i) an interior of the second portion, and/or (ii) a space formed between the first and second portions. A third portion of the device includes a third polymer that is bondable to the first and second polymers and fixedly secures the first and second portions to each other.

摘要翻译： 一种装置包括包含第一聚合物的第一部分和与第一部分相比具有相对柔性的第二部分，并且包括基本上不能与第一聚合物结合的第二聚合物。 该装置的腔室相对于环境气氛可气密地密封，并且由（i）第二部分的内部和/或（ii）形成在第一和第二部分之间的空间限定。 该装置的第三部分包括可与第一和第二聚合物结合的第三聚合物，并将第一和第二部分彼此固定地固定。

公开(公告)号：US20140246462A1

公开(公告)日：2014-09-04

申请号：US14101981

申请日：2013-12-10

申请人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

发明人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

IPC分类号： B65D37/00

CPC分类号： B67D1/108 ,  B05B11/00444 ,  B65B39/004 ,  B65D51/002 ,  B65D51/1616 ,  B67D1/0004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/0801 ,  B67D1/10 ,  B67D1/1279 ,  B67D3/0067 ,  B67D3/04 ,  B67D2001/0827 ,  F04B53/1037

摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

摘要翻译： 提供了一种柔性袋和阀组件，用于无菌存储物质，从其中分配多部分储存物质，并将残留在袋中的物质保持在相对于环境大气密封的无菌状态。 柔性袋和阀组件可接收在相对刚性的壳体内，并且适于与泵协作，用于泵送物质的离散部分并且通过单向阀从其分配物质。 组件包括柔性袋，其中限定有相对于环境大气密封的可变容积存储室，用于将物质的多个部分无菌存储。 组件的单向阀包括限定轴向延伸的阀座的阀体和延伸穿过阀体和/或阀座的至少一个流动孔。

公开(公告)号：US08631838B2

公开(公告)日：2014-01-21

申请号：US13326177

申请日：2011-12-14

申请人： Daniel Py

发明人： Daniel Py

IPC分类号： B65B1/20 ,  A61J1/20

CPC分类号： A61J1/2096 ,  A61J1/1406 ,  A61J1/1468 ,  A61J1/18 ,  A61L2/08 ,  B29C65/16 ,  B29C65/1616 ,  B29C65/1619 ,  B29C65/1654 ,  B29C65/1677 ,  B29C65/18 ,  B29C66/001 ,  B29C66/1222 ,  B29C66/1224 ,  B29C66/12461 ,  B29C66/1312 ,  B29C66/342 ,  B29C66/534 ,  B29C66/5344 ,  B29C66/542 ,  B29C66/612 ,  B29C66/71 ,  B29C66/73755 ,  B29C66/7392 ,  B29C66/73921 ,  B29C66/7394 ,  B29C66/8322 ,  B29C67/004 ,  B29L2031/7158 ,  B29L2031/753 ,  B65B3/003 ,  B65B7/161 ,  B65D51/002 ,  B29C65/00 ,  B29K2025/08 ,  B29K2023/00

摘要： Device and method for needle penetrating and filling a chamber with a predetermined substance, and hermetically resealing a resulting needle hole in the device by applying radiation thereto. The needle penetrable and resealable portion defines a predetermined wall thickness in an axial direction thereof, and may include a thermoplastic that substantially prevents the formation of particles released into the chamber from the needle penetrable and resealable portion during penetration by and withdrawal of the needle. Such thermoplastic may include a predetermined amount of pigment that allows the thermoplastic to substantially absorb laser radiation at a predetermined wavelength, substantially prevent the passage of radiation through the predetermined wall thickness thereof, and hermetically seal a needle aperture formed in the needle penetration region thereof in a predetermined time period.

摘要翻译： 用于穿刺和填充具有预定物质的腔室的装置和方法，并且通过向其施加辐射气密地重新密封装置中的所得针孔。 针穿透和可重新密封的部分在其轴向方向上限定预定的壁厚，并且可以包括热塑性材料，其基本上防止在穿透和抽出针时从针穿透和可再密封部分释放到腔中的颗粒的形成。 这种热塑性材料可以包括预定量的颜料，其允许热塑性塑料基本上吸收预定波长的激光辐射，基本上防止辐射通过其预定壁厚，并将形成在其针穿入区域中的针孔气密地密封在 预定时间段。

公开(公告)号：US08602259B2

公开(公告)日：2013-12-10

申请号：US13362532

申请日：2012-01-31

申请人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

发明人： Daniel Py ,  Julian V. Chan ,  Benoit Adamo ,  Nathaniel Houle

IPC分类号： B67D7/14

CPC分类号： B67D1/108 ,  B05B11/00444 ,  B65B39/004 ,  B65D51/002 ,  B65D51/1616 ,  B67D1/0004 ,  B67D1/0007 ,  B67D1/0009 ,  B67D1/0082 ,  B67D1/0801 ,  B67D1/10 ,  B67D1/1279 ,  B67D3/0067 ,  B67D3/04 ,  B67D2001/0827 ,  F04B53/1037

摘要： A flexible pouch and valve assembly is provided for aseptically storing a substance, dispensing multiple portions of the stored substance therefrom, and maintaining substance remaining in the pouch in an aseptic condition sealed with respect to ambient atmosphere. The flexible pouch and valve assembly are receivable within a relatively rigid housing, and are adapted to cooperate with a pump for pumping discrete portions of substance from the pouch and through the one-way valve to dispense the substance therefrom. The assembly comprises a flexible pouch defining therein a variable-volume storage chamber sealed with respect to the ambient atmosphere for aseptically storing therein multiple portions of the substance. A one-way valve of the assembly includes a valve body defining an axially-extending valve seat and at least one flow aperture extending through the valve body and/or the valve seat.

公开(公告)号：US08596314B2

公开(公告)日：2013-12-03

申请号：US12259279

申请日：2008-10-27

申请人： Daniel Py ,  Julian Chan ,  Jeffrey Willey

发明人： Daniel Py ,  Julian Chan ,  Jeffrey Willey

IPC分类号： B65B3/04 ,  A61J9/00 ,  A61J11/04 ,  B65D25/40

CPC分类号： B65D47/36 ,  A61J1/202 ,  A61J9/00 ,  A61J9/008 ,  A61J11/04 ,  B65B3/04 ,  B65D47/063 ,  B65D47/265 ,  B65D47/32 ,  B65D51/002

摘要： A container including a body defining an outflow opening and at least one chamber adapted for storing a product, such as a fat containing liquid product, and a container closure including a primary seal for hermetically sealing the product within the chamber during storage. The container closure includes a sealing member forming a substantially fluid-tight seal between the container closure and the body, and a dispensing member in fluid communication with the chamber. The container closure and body move relative to each other between a first position where the primary seal is seated about the outflow port to hermetically seal the product in the chamber during storage, and a second position where the primary seal is displaced from the outflow port to allow product to pass from the chamber through the outflow port and into dispensing member to dispense the product.

摘要翻译： 一种容器，其包括限定流出开口的主体和适于储存产品（例如含脂肪的液体产品）的至少一个室，以及容器盖，该容器封闭件包括用于在储存期间气密地密封室内的产品的主密封件。 容器封闭件包括在容器封闭件和主体之间形成基本上流体密封的密封件和与腔室流体连通的分配构件的密封构件。 容器封闭件和主体在第一位置和第二位置之间移动，第一位置和第二位置之间，第一位置处主要密封件围绕流出端口安置，以便在存储期间将产品气密地密封在腔室中;以及第二位置，其中主密封件从流出端口移位到 允许产品从腔室通过流出口并进入分配构件以分配产品。

公开(公告)号：US20130184677A1

公开(公告)日：2013-07-18

申请号：US13743661

申请日：2013-01-17

申请人： Daniel Py

发明人： Daniel Py

IPC分类号： A61M5/315 ,  A61J7/00 ,  A61M5/178

CPC分类号： A61M5/31593 ,  A61J7/0053 ,  A61M5/1782 ,  A61M5/204 ,  A61M2005/3126 ,  A61M2005/3128 ,  B05B9/0426 ,  B05B11/00416 ,  B05B11/007 ,  B05B11/0072 ,  B05B11/3015 ,  B05B11/3028 ,  B05B11/3064 ,  B05B11/3077 ,  B65D83/7535 ,  G01F11/02 ,  G01F11/025 ,  G01F11/027 ,  G01F11/028

摘要： A multiple dose syringe has a first valve defining a first valve opening pressure and a second valve defining a second valve opening pressure. A storage chamber in fluid communication with the second valve stores multiple doses of a substance therein and includes an outlet for dispensing multiple doses of the stored substance therethrough. A compression surface is movable between first and second positions and defines a compression chamber between the compression surface and the first valve. Movement of the compression surface in a direction from the first position toward the second position dispenses substance in the compression chamber through the first valve and out of the syringe. Movement of the compression surface in a direction from the second position toward the first position causes substance to flow from the storage chamber through the second valve and into the compression chamber.

摘要翻译： 多剂量注射器具有限定第一阀开启压力的第一阀和限定第二阀开启压力的第二阀。 与第二阀流体连通的储存室在其中存储多种剂量的物质，并且包括用于通过其分配多剂量的储存物质的出口。 压缩表面可在第一和第二位置之间移动，并且在压缩表面和第一阀之间限定压缩室。 压缩表面在从第一位置朝向第二位置的方向上的运动通过第一阀和注射器分配压缩室中的物质。 压缩表面在从第二位置朝向第一位置的方向上的移动使得物质从存储室通过第二阀流入压缩室。