公开(公告)号：US08349845B2

公开(公告)日：2013-01-08

申请号：US11917425

申请日：2006-06-19

Applicant: Fei-Yue Zhao ,  Alistair Kerr Dixon ,  Jonathan Mark Treherne ,  Chizuko Koseki ,  Kevin Lee ,  David Spanswick

Inventor： Fei-Yue Zhao ,  Alistair Kerr Dixon ,  Jonathan Mark Treherne ,  Chizuko Koseki ,  Kevin Lee ,  David Spanswick

IPC: A61K31/519 ,  A61K43/00 ,  A61K31/535

CPC classification number: A61K31/519

Abstract: Use of a compound of formula (I) wherein R is an alicyclic group; an arylethyl group; or phenyl or benzyl substituted by halogen, lower alkyl, alkoxy, OH, NH2, NHalkyl, N(alkyl)2, CN or NO2; in the manufacture of a medicament for the therapy of hyperalgesic pain conditions and their symptoms.

Abstract translation: 其中R是脂环族基团的式（I）化合物的用途; 芳基乙基; 或被卤素，低级烷基，烷氧基，OH，NH 2，NH烷基，N（烷基）2，CN或NO 2取代的苯基或苄基; 在制备用于治疗痛觉过敏性疼痛症状及其症状的药物中。

公开(公告)号：US20100216819A1

公开(公告)日：2010-08-26

申请号：US11917425

申请日：2006-06-19

Applicant: Fei-Yeu Zhao ,  Alistair Kerr Dixon ,  Jonathan Mark Treherne ,  Chizuko Koseki ,  Kevin Lee ,  David Spanswick

Inventor： Fei-Yeu Zhao ,  Alistair Kerr Dixon ,  Jonathan Mark Treherne ,  Chizuko Koseki ,  Kevin Lee ,  David Spanswick

IPC: A61K31/519 ,  A61P19/02 ,  A61P29/00 ,  A61P13/00

CPC classification number: A61K31/519

Abstract: Use of a compound of formula (I) wherein R is an alicyclic group; an arylethyl group; or phenyl or benzyl substituted by halogen, lower alkyl, alkoxy, OH, NH2, NHalkyl, N(alkyl)2, CN or NO2; in the manufacture of a medicament for the therapy of hyperalgesic pain conditions and their symptoms.

Abstract translation: 其中R是脂环族基团的式（I）化合物的用途; 芳基乙基; 或被卤素，低级烷基，烷氧基，OH，NH 2，NH烷基，N（烷基）2，CN或NO 2取代的苯基或苄基; 在制备用于治疗痛觉过敏性疼痛症状及其症状的药物中。