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公开(公告)号:US20120265297A1
公开(公告)日:2012-10-18
申请号:US13420356
申请日:2012-03-14
CPC分类号: A61F2/12 , A61K8/64 , A61K38/1767 , A61K47/42 , A61K2800/5922 , A61K2800/91 , A61L27/227 , A61L27/26 , A61L27/52 , A61L2430/34 , A61Q19/00 , C08B37/0072 , C08L89/00
摘要: The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such molecules, methods of making fibroin hydrogels, fibroin hydrogels and fibroin hydrogel formulations useful for a variety of medical uses, including, without limitation uses as bulking agents, tissue space fillers, templates for tissue reconstruction or regeneration, cell culture scaffolds for tissue engineering and for disease models, surface coating to improve medical device function, or drug delivery devices.
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公开(公告)号:US20110008406A1
公开(公告)日:2011-01-13
申请号:US12764050
申请日:2010-04-20
CPC分类号: A61F2/12 , A61K8/64 , A61K38/1767 , A61K47/42 , A61K2800/5922 , A61K2800/91 , A61L27/227 , A61L27/26 , A61L27/52 , A61L2430/34 , A61Q19/00 , C08B37/0072 , C08L89/00
摘要: The present specification provides for methods for purifying fibroins, purified fibroins, methods of conjugating biological and synthetic molecules to fibroins, fibroins conjugated to such molecules, methods of making fibroin hydrogels, fibroin hydrogels and fibroin hydrogel formulations useful for a variety of medical uses, including, without limitation uses as bulking agents, tissue space fillers, templates for tissue reconstruction or regeneration, cell culture scaffolds for tissue engineering and for disease models, surface coating to improve medical device function, or drug delivery devices.
摘要翻译: 本说明书提供了用于纯化丝心蛋白,纯化的丝心蛋白,将生物和合成分子与丝心蛋白缀合的方法,与此类分子缀合的丝心蛋白,制备丝心蛋白水凝胶的方法,丝心蛋白水凝胶和用于各种医疗用途的丝心蛋白水凝胶制剂的方法,包括 ,但不限于用作填充剂,组织空间填充剂,用于组织重建或再生的模板,用于组织工程和疾病模型的细胞培养支架,用于改善医疗装置功能的表面涂层或药物递送装置。
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