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公开(公告)号：US08987248B2
公开(公告)日：2015-03-24
申请号：US13202707
申请日：2010-03-12
Applicant: Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
Inventor： Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
IPC: A61K31/5377 , C07D413/06 , C07D211/60 , C07D211/42 , C07D211/56 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/06
CPC classification number: C07D417/06 , A61K9/0019 , A61K9/10 , A61K9/2018 , A61K31/451 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K47/10 , A61K47/36 , C07D211/42 , C07D211/56 , C07D211/60 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12
Abstract: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumor disorders.
Abstract translation: 本发明涉及新的取代的哌啶，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病，特别是心血管疾病和肿瘤的药物的用途 疾病
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公开(公告)号：US20120149694A1
公开(公告)日：2012-06-14
申请号：US13321790
申请日：2010-05-14
Applicant: Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Ulrich Rester , Eckhard Bender , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
Inventor： Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Ulrich Rester , Eckhard Bender , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
IPC: A61K31/541 , C07D413/14 , A61P35/00 , A61K31/5377 , A61P7/02 , A61P9/00 , C07D413/06 , C07D417/06
CPC classification number: C07D211/34 , C07D211/20 , C07D211/22 , C07D211/24 , C07D211/26 , C07D401/06 , C07D417/06
Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.
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公开(公告)号：US20120046268A1
公开(公告)日：2012-02-23
申请号：US13202707
申请日：2010-03-12
Applicant: Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
Inventor： Mario Jeske , Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Kersten Matthias Gericke
IPC: A61K31/4523 , C07D405/06 , C07D401/06 , C07D417/06 , C07D413/06 , A61K31/445 , A61K31/453 , A61K31/4525 , A61K31/454 , A61K31/4545 , A61K31/5377 , A61K31/496 , A61K31/541 , A61P7/02 , C12N5/078 , C07D211/60
CPC classification number: C07D417/06 , A61K9/0019 , A61K9/10 , A61K9/2018 , A61K31/451 , A61K31/4523 , A61K31/4525 , A61K31/453 , A61K31/454 , A61K31/4545 , A61K31/496 , A61K31/5377 , A61K31/541 , A61K47/10 , A61K47/36 , C07D211/42 , C07D211/56 , C07D211/60 , C07D211/62 , C07D401/06 , C07D405/06 , C07D405/12 , C07D409/12 , C07D413/12
Abstract: The invention relates to novel substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular disorders and tumour disorders.
Abstract translation: 本发明涉及新的取代的哌啶，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病，特别是心血管疾病和肿瘤的药物的用途 疾病
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公开(公告)号：US20110021489A1
公开(公告)日：2011-01-27
申请号：US12788529
申请日：2010-05-27
Applicant: Dirk HEIMBACH , Susanne Röhrig , Yolanda Cancho Grande , Eckhard Bender , Katja Zimmermann , Anja Buchmüller , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
Inventor： Dirk HEIMBACH , Susanne Röhrig , Yolanda Cancho Grande , Eckhard Bender , Katja Zimmermann , Anja Buchmüller , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
IPC: A61K31/397 , C07D401/04 , A61K31/454 , C07D413/14 , C07D417/14 , A61K31/541 , C07D401/14 , A61K31/4545 , A61K31/5377 , A61P7/02
CPC classification number: C07D413/04 , C07D413/14
Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.
Abstract translation: 本发明涉及新型取代的哌啶，其制备方法，其用于治疗和/或预防疾病的用途及其用于生产用于治疗和/或预防疾病，特别是心血管疾病和肿瘤的药物的用途 疾病
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公开(公告)号：US20120220563A1
公开(公告)日：2012-08-30
申请号：US13321966
申请日：2010-05-19
Applicant: Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Eckhard Bender , Katja Zimmermann , Anja Buchmüller , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
Inventor： Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Eckhard Bender , Katja Zimmermann , Anja Buchmüller , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
IPC: A61K31/454 , A61K31/5377 , A61K31/4545 , C07D417/14 , A01N1/02 , C07D413/04 , A61P7/02 , A61P9/00 , A61P35/00 , C07D413/14 , A61K31/541
CPC classification number: C07D413/04 , C07D413/14
Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular disorders and tumour disorders.
Abstract translation: 本发明涉及新型取代的哌啶，其制备方法，其用于治疗和/或预防疾病的用途及其用于生产用于治疗和/或预防疾病，特别是心血管疾病和肿瘤的药物的用途 疾病
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Patent Agency Ranking
公开(公告)号：US20100305111A1
公开(公告)日：2010-12-02
申请号：US12788641
申请日：2010-05-27
Applicant: Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Eckhard Bender , Katja Zimmermann , Anja Buchmüller , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
Inventor： Dirk Heimbach , Susanne Röhrig , Yolanda Cancho Grande , Eckhard Bender , Katja Zimmermann , Anja Buchmüller , Christoph Gerdes , Mark Jean Gnoth , Kersten Matthias Gericke , Mario Jeske
IPC: A61K31/541 , C07D419/14 , A61P7/02
CPC classification number: C07D413/04 , C07D417/14
Abstract: The invention relates to novel substituted piperidines, to processes for preparation thereof, to the use thereof for treatment and/or prophylaxis of diseases and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially of cardiovascular diseases and tumour diseases.
Abstract translation: 本发明涉及新型取代的哌啶，其制备方法，其用于治疗和/或预防疾病的用途及其用于生产用于治疗和/或预防特别是心血管疾病和肿瘤的疾病的药物的用途 疾病
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公开(公告)号：US20080004275A1
公开(公告)日：2008-01-03
申请号：US10594343
申请日：2005-03-11
Applicant: Holger Zimmermann , David Bruckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Jorg Keldenich , Dieter Lang , Martin Radtke
Inventor： Holger Zimmermann , David Bruckner , Dirk Heimbach , Martin Hendrix , Kerstin Henninger , Guy Hewlett , Ulrich Rosentreter , Jorg Keldenich , Dieter Lang , Martin Radtke
IPC: A61K31/5377 , A61K31/4155 , A61K31/4178 , A61K31/4184 , A61P31/12 , C07D233/88 , C07D249/12 , C07D403/12 , C07D413/12 , C07D401/12 , C07D249/04 , C07D233/44 , A61K31/4192 , A61K31/4196 , A61K31/4439
CPC classification number: C07D233/90 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12
Abstract: The invention relates to the substituted imidazoles of formula (I) and to methods for producing the same, to their use in the treatment and/or prophylaxis of diseases and to their use for producing drugs for use in the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, especially against cytomegaloviruses.
Abstract translation: 本发明涉及式（I）的取代的咪唑及其制备方法，用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病的药物的用途 特别是用作抗病毒药物，特别是针对巨细胞病毒。
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公开(公告)号：US08318761B2
公开(公告)日：2012-11-27
申请号：US12203793
申请日：2008-09-03
Applicant: Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
Inventor： Niels Svenstrup , Holger Zimmermann , Dagmar Karthaus , Andreas Goeller , Dirk Heimbach , Kerstin Henninger , Dieter Lang , Daniela Paulsen , Bernd Riedl , Rudolf Schohe-Loop , Joachim Schuhmacher , Tobias Wunberg
IPC: A01N43/40 , A61K31/435 , A61K31/44
CPC classification number: C07D413/04 , C07D213/73
Abstract: The invention relates to substituted arylsulfonamides of formula (I) and methods for their preparation as well as their use for the production of medicaments for the treatment and/or prophylaxis of diseases, especially for use as antiviral agents, particularly against cytomegaloviruses.
Abstract translation: 本发明涉及式（I）的取代芳基磺酰胺及其制备方法及其用于生产用于治疗和/或预防疾病的药物的用途，特别是用作抗病毒剂，特别是用于巨细胞病毒的药物。
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公开(公告)号：US20120214788A1
公开(公告)日：2012-08-23
申请号：US13400491
申请日：2012-02-20
Applicant: Dirk Heimbach , Susanne Röhrig , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Yolanda Cancho Grande , Mario Jeske , Kersten Matthias Gericke
Inventor： Dirk Heimbach , Susanne Röhrig , Dirk Schneider , Ulrich Rester , Eckhard Bender , Mark Meininghaus , Katja Zimmermann , Dmitry Zubov , Anja Buchmüller , Georges Von Degenfeld , Christoph Gerdes , Michael Gerisch , Mark Jean Gnoth , Yolanda Cancho Grande , Mario Jeske , Kersten Matthias Gericke
IPC: A61K31/454 , A61P9/10 , A61P7/00 , A61K31/5377 , A61K31/4545
CPC classification number: C07D413/04 , C07D413/14 , C07D417/14
Abstract: The invention relates to novel heteroaryl-substituted piperidines, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of cardiovascular diseases and tumour diseases.
Abstract translation: 本发明涉及新颖的杂芳基取代的哌啶，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病，特别是心血管疾病的药物的用途 和肿瘤疾病。
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公开(公告)号：US20100184740A1
公开(公告)日：2010-07-22
申请号：US12665729
申请日：2008-06-07
Applicant: Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Jean Gnoth , Christoph Gerdes , Georges Von Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatman , Adrian Tersteegen
Inventor： Swen Allerheiligen , Marcus Bauser , Dirk Heimbach , Stefan Heitmeier , Mark Jean Gnoth , Christoph Gerdes , Georges Von Degenfeld , Susanne Röhrig , Ulrich Rester , Elke Dittrich-Wengenroth , Uwe Saatman , Adrian Tersteegen
IPC: A61K31/4439 , C07D413/14 , A61K31/5377 , A61K31/496 , C07D417/14 , A61K31/541 , A61K31/553 , A61P7/02 , A61P7/00 , A61P9/12 , A61P29/00
CPC classification number: C07D413/14
Abstract: The invention relates to novel substituted oxazolidinones, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular of thromboembolic disorders.
Abstract translation: 本发明涉及新的取代的恶唑烷酮，其制备方法，其用于治疗和/或预防疾病及其用于制备用于治疗和/或预防疾病，特别是血栓栓塞性疾病的药物的用途。
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