公开(公告)号：US09726676B2

公开(公告)日：2017-08-08

申请号：US13825729

申请日：2011-09-20

申请人： Niels Grabe ,  Niels Halama ,  Dirk Jaeger ,  Inka Zoernig

发明人： Niels Grabe ,  Niels Halama ,  Dirk Jaeger ,  Inka Zoernig

IPC分类号： G01N33/68 ,  G01N33/50 ,  G01N33/574

CPC分类号： G01N33/6893 ,  G01N33/5011 ,  G01N33/5091 ,  G01N33/574 ,  G01N2333/7051 ,  G01N2333/70517 ,  G01N2333/96436 ,  G01N2800/52

摘要： The present invention relates to the field of treatment efficacy prediction in patients with malignant diseases. More precisely, this invention relates to the prediction of the efficacy of a treatment in cancer patients, based on the precise quantification of several biological markers that are related to the innate and adaptive immune response of said patient against said cancer.

公开(公告)号：US20110123447A1

公开(公告)日：2011-05-26

申请号：US12450101

申请日：2008-03-13

申请人： Christoph Esslinger ,  Sandra Kuenzle ,  Irene Abela ,  Roger Nitsch ,  Holger Moch ,  Norbert Goebels ,  Dirk Jaeger ,  Alfred Zippelius ,  Alexander Knuth

发明人： Christoph Esslinger ,  Sandra Kuenzle ,  Irene Abela ,  Roger Nitsch ,  Holger Moch ,  Norbert Goebels ,  Dirk Jaeger ,  Alfred Zippelius ,  Alexander Knuth

IPC分类号： A61K39/395 ,  G01N33/53 ,  C12P21/00 ,  C07K16/18 ,  C07K14/47 ,  C07H21/00 ,  C12N15/63 ,  C12N5/10 ,  C12N9/96 ,  A61P35/00 ,  A61K49/00

CPC分类号： C07K16/30 ,  A61K45/06 ,  A61K49/0002 ,  C07K16/3053 ,  C07K2317/21

摘要： Provided are novel tumor-specific binding molecules, particularly human antibodies as well as fragments, derivatives and variants thereof that recognize tumor-associated antigens and that are obtained from a tumor patient who shows at least partial clinical response or is symptom-free. In addition, pharmaceutical compositions comprising such binding molecules, antibodies and mimics thereof and methods of screening for novel binding molecules, which may or may not be antibodies as well as targets in the treatment of tumors are described.

摘要翻译： 提供了新的肿瘤特异性结合分子，特别是人抗体以及识别肿瘤相关抗原的片段，衍生物和变体，并且其从显示至少部分临床反应或无症状的肿瘤患者获得。 此外，描述了包含这样的结合分子，抗体及其模拟物的药物组合物以及筛选新结合分子的方法，其可以是或可以不是抗体以及肿瘤治疗中的靶标。

公开(公告)号：US20130052873A1

公开(公告)日：2013-02-28

申请号：US13592205

申请日：2012-08-22

申请人： Dirk-Jan RIEZEBOS ,  Peter Dirk JAEGER ,  Wijnand VAN GILS ,  Jan BROEKSTEEG

发明人： Dirk-Jan RIEZEBOS ,  Peter Dirk JAEGER ,  Wijnand VAN GILS ,  Jan BROEKSTEEG

IPC分类号： H01R13/719

CPC分类号： H01R27/00 ,  H01R13/35 ,  H01R13/6625 ,  H01R13/6633 ,  H01R24/58 ,  H01R2201/02

摘要： The invention relates to socket connectors and socket connector systems for electrically connecting a first corresponding plug connector and for capacitively connecting a second corresponding plug connector. Further, the invention relates to a plug connector for capacitively connecting a corresponding socket connector. In order to allow for an electrical connection or a capacitive connection, the invention suggest providing a connecting element, arranged within the housing of the socket connector, including contact portion for contacting a connection area of the first plug connector, and a non-contact portion arranged such that, in the mated state, the surface thereof covers at least parts of a connection area of the second plug connector.

摘要翻译： 本发明涉及插座连接器和插座连接器系统，用于电连接第一对应插头连接器和用于电容连接第二对应插头连接器。 此外，本发明涉及用于电容连接相应插座连接器的插头连接器。 为了允许电连接或电容连接，本发明建议提供一种设置在插座连接器的壳体内的连接元件，包括用于接触第一插头连接器的连接区域的接触部分和非接触部分 布置成使得在配合状态下，其表面覆盖第二插头连接器的连接区域的至少一部分。

公开(公告)号：US08152558B2

公开(公告)日：2012-04-10

申请号：US12734633

申请日：2008-11-10

申请人： Johannes Marcelus Broeksteeg ,  Lieven Decrock ,  Peter Dirk Jaeger

发明人： Johannes Marcelus Broeksteeg ,  Lieven Decrock ,  Peter Dirk Jaeger

IPC分类号： H01R13/64 ,  H04M1/00

CPC分类号： H01R31/06 ,  B60R11/0241 ,  H01R9/03 ,  H01R9/032 ,  H01R13/6593 ,  H01R24/545 ,  H01R24/568 ,  H01R2107/00 ,  H01R2201/16 ,  H01R2201/26 ,  Y10S439/929

摘要： The present invention relates to a universal serial bus (USB) connector for use in a base unit in a car kit comprising at least two pairs of shielded connection lines. It further relates to a USB cable for providing a shielded connection between a mobile unit and a car kit adaptor. The USB connector for use in a base unit in a car-kit comprises two twin axial connectors (430) including two inner contacts separated by a dielectric and further adapted to be connected to respective complementary connectors and two pairs of shielded connection lines (104 and 104′). Each pair is connected to a twin axial connector (430). Further, a shielded USB bridge (100) connects the two pairs of connection lines (104 and 104′) to four cable terminations (106) to form a USB line (108). The bridge (100) is mounted in the base unit (400′) with the twin axial connectors (430) located in modified guide gins (441) that extend from the base unit.

摘要翻译： 本发明涉及一种用于汽车套件中的基本单元中的通用串行总线（USB）连接器，其包括至少两对屏蔽连接线。 它还涉及一种用于在移动单元和汽车套件适配器之间提供屏蔽连接的USB电缆。 用于汽车套件中的基座单元的USB连接器包括两个双向轴向连接器（430），包括两个由电介质隔开的内部触头，并且还可以连接到相应的互补连接器和两对屏蔽连接线（104和 104'）。 每对连接到双轴向连接器（430）。 此外，屏蔽的USB桥（100）将两对连接线（104和104'）连接到四个电缆终端（106）以形成USB线（108）。 桥接器（100）安装在基座单元（400'）中，双轴向连接器（430）位于从基座单元延伸的改进的引导金属丝（441）中。

公开(公告)号：US08950548B2

公开(公告)日：2015-02-10

申请号：US13818521

申请日：2011-01-28

申请人： Marco Schneider ,  Dirk Jaeger ,  Volker Kursch ,  Edmund Sumann ,  Norbert Nicolai ,  Volkmar Schulze

发明人： Marco Schneider ,  Dirk Jaeger ,  Volker Kursch ,  Edmund Sumann ,  Norbert Nicolai ,  Volkmar Schulze

IPC分类号： E04B1/84 ,  E04B1/82 ,  B60R13/08 ,  G10K11/162 ,  E04B1/74

CPC分类号： E04B1/8409 ,  B60R13/0815 ,  G10K11/162

摘要： The invention relates to a broadband sound absorber (1) which comprises a sound-absorbing filler material between two microperforated film webs (2) which are contiguous on their edges, said filler material optionally containing heavy fillers. The broadband sound absorber (1) achieves excellent acoustic insulation and has microperforations (4) all over or only in sections, said filler material optionally containing heavy fillers (mass density) and one or both microperforated film webs (2) having the same thickness across their surface or thickened portions (3, 5) of the same or a different material in some sections.

摘要翻译： 本发明涉及一种宽带吸声器（1），其包括两个在其边缘上相邻的微穿孔薄膜腹板（2）之间的吸声填料，所述填充材料任选地包含重填料。 宽带吸声器（1）具有优异的隔音性能，并且在整个或整个部分都具有微穿孔（4），所述填充材料任选地包含重的填料（质量密度）和一个或两个具有相同厚度的微孔膜（2） 它们的表面或加厚部分（3,5）在一些部分中是相同的或不同的材料。

公开(公告)号：US20130153331A1

公开(公告)日：2013-06-20

申请号：US13818521

申请日：2011-01-28

申请人： Marco Schneider ,  Dirk Jaeger ,  Volker Kursch ,  Edmund Sumann ,  Norbert Nicolai ,  Volkmar Schulze

发明人： Marco Schneider ,  Dirk Jaeger ,  Volker Kursch ,  Edmund Sumann ,  Norbert Nicolai ,  Volkmar Schulze

IPC分类号： E04B1/84

CPC分类号： E04B1/8409 ,  B60R13/0815 ,  G10K11/162

摘要： The invention relates to a broadband sound absorber (1) which comprises a sound-absorbing filler material between two microperforated film webs (2) which are contiguous on their edges, said filler material optionally containing heavy fillers. The broadband sound absorber (1) achieving excellent acoustic insulation comprises a sound-absorbing filler material between two film webs (2) which are contiguous on their edges and have microperforations (4) all over or only in sections, said filler material optionally containing heavy fillers (mass density) and one or both microperforated film webs (2) having the same thickness across their surface or thickened portions (3, 5) of the same or a different material in some sections.

摘要翻译： 本发明涉及一种宽带吸声器（1），其包括两个在其边缘上相邻的微穿孔薄膜腹板（2）之间的吸声填料，所述填充材料任选地包含重填料。 实现优异隔音的宽带吸声器（1）包括在两个薄膜腹板（2）之间的吸声填充材料，它们在其边缘上是连续的，并且全部或仅在部分上具有微穿孔（4），所述填充材料任选地包含重的 填料（质量密度）和一个或两个具有相同厚度的微穿孔薄膜腹板（2），在其一些部分中具有相同厚度或相同或不同材料的加厚部分（3,5）。

公开(公告)号：US07946856B2

公开(公告)日：2011-05-24

申请号：US12640902

申请日：2009-12-17

申请人： Peter Dirk Jaeger

发明人： Peter Dirk Jaeger

IPC分类号： H01R12/00

CPC分类号： H01R12/714 ,  Y10T29/49147

摘要： The invention relates to a connector for electrically connecting at least one terminal arranged on a surface of a surface-mount device to a corresponding substrate contact of a circuit substrate. The connector for electrically includes at least one resilient electrically conductive interconnection element being connectable to the at least one substrate contact and configured to establish a releasable electrical contact with the at least one terminal, and a connector housing for mounting the at least one interconnection element. The interconnection element is affixed to the housing by means of a foil-shaped carrier.

摘要翻译： 本发明涉及一种用于将布置在表面安装器件的表面上的至少一个端子电连接到电路基板的相应衬底接触件的连接器。 用于电气的连接器包括至少一个弹性导电互连元件，其可连接到所述至少一个基板触点并被配置成与所述至少一个端子建立可释放的电接触，以及用于安装所述至少一个互连元件的连接器壳体。 互连元件通过箔形载体固定在外壳上。

公开(公告)号：US20100232747A1

公开(公告)日：2010-09-16

申请号：US12722049

申请日：2010-03-11

申请人： Jeroen Duis ,  Jacob Arie Elenbaas ,  Peter Dirk Jaeger

发明人： Jeroen Duis ,  Jacob Arie Elenbaas ,  Peter Dirk Jaeger

IPC分类号： G02B6/36

CPC分类号： G02B6/3809 ,  G02B6/3898 ,  G02B6/4292

摘要： The invention refers to an optical fiber connector with a support member and a ferrule for receiving an optical fiber and fixed to the support member. The optical fiber is embedded in the ferrule. An end face of the optical fiber is arranged on the support member, while an alignment element is connected with the support member. The end face of the optical fiber abuts with the alignment element, whereby the alignment element aligns the end face of the optical fiber relative to a predetermined optical path.

摘要翻译： 本发明涉及具有支撑构件和用于容纳光纤并固定到支撑构件的套圈的光纤连接器。 光纤嵌入在套圈中。 光纤的端面设置在支撑部件上，而对准元件与支撑部件连接。 光纤的端面与对准元件抵接，由此对准元件相对于预定的光路对准光纤的端面。

公开(公告)号：US20080218946A1

公开(公告)日：2008-09-11

申请号：US12065064

申请日：2006-08-17

申请人： Malcolm Cant ,  Jan Van Tilburg ,  Peter Dirk Jaeger

发明人： Malcolm Cant ,  Jan Van Tilburg ,  Peter Dirk Jaeger

IPC分类号： H02B13/02

CPC分类号： H02G5/04 ,  H01R25/142

摘要： A bus-bar having a prismatic housing, an elongate conductor extending along a length of the housing, and a resilient retainer which extends along a length of the housing and retains the conductor in the housing is disclosed.

摘要翻译： 公开了一种具有棱柱形壳体的母线，沿着壳体的长度延伸的细长导体，以及沿壳体的长度延伸并将导体保持在壳体中的弹性保持器。

公开(公告)号：US07140895B2

公开(公告)日：2006-11-28

申请号：US11172577

申请日：2005-06-30

申请人： Jacobus Nicolaas Tuin ,  Peter Dirk Jaeger

发明人： Jacobus Nicolaas Tuin ,  Peter Dirk Jaeger

IPC分类号： H01R4/56

CPC分类号： H01R13/113 ,  H01R12/57 ,  H01R12/7088 ,  H01R12/727 ,  H01R13/14 ,  H01R13/6315 ,  H04M1/0262

摘要： A receptacle connector comprises at least one receptacle contact. The receptacle contact includes a contact member and at least one spring member. The contact member is formed for receipt of a plug contact along a mating plane. The contact member is resiliently displaceable in a direction substantial lateral to the mating plane by the spring member.

摘要翻译： 插座连接器包括至少一个插座触点。 插座触点包括接触构件和至少一个弹簧构件。 接触构件形成为沿着配合平面接收插头接触。 接触构件可以通过弹簧构件在配合平面的大致横向的方向上弹性移位。