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公开(公告)号：US08642531B2
公开(公告)日：2014-02-04
申请号：US12201894
申请日：2008-08-29
CPC分类号： A61K47/4833 , A61K39/12 , A61K39/145 , A61K39/21 , A61K39/385 , A61K47/54 , A61K47/58 , A61K47/646 , A61K2039/54 , A61K2039/55511 , A61K2039/60 , A61K2039/6018 , A61K2039/6031 , C07K14/005 , C12N2740/16122 , C12N2740/16134 , C12N2760/16034 , C12N2760/16122 , C12N2760/16222 , C12N2760/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of influenza antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-influenza antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals, including humans.
摘要翻译： 本发明涉及用于将流感抗原递送至免疫反应性靶细胞的碳氟载体。 它进一步涉及氟碳载体 - 流感抗原构建体，以及在动物（包括人）中使用与抗原相关的载体作为疫苗和免疫治疗剂。
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公开(公告)号：US20120034259A1
公开(公告)日：2012-02-09
申请号：US12207828
申请日：2008-09-10
CPC分类号： A61K47/48023 , A61K31/02 , A61K38/02 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K47/54 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/5555 , A61K2039/55566 , A61K2039/60 , A61K2039/6018 , C07C19/08 , C07C57/52 , C07K2/00 , C07K14/005 , C12N7/00 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
摘要翻译： 本发明涉及用于将抗原递送至免疫反应性靶细胞的碳氟载体。 它还涉及碳氟载体 - 抗原构建体以及与抗原相关的这种载体作为动物疫苗和免疫治疗剂的用途。
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公开(公告)号：US08110541B2
公开(公告)日：2012-02-07
申请号：US12700566
申请日：2010-02-04
CPC分类号： A61K47/48023 , A61K31/02 , A61K38/02 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K47/54 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/5555 , A61K2039/55566 , A61K2039/60 , A61K2039/6018 , C07C19/08 , C07C57/52 , C07K2/00 , C07K14/005 , C12N7/00 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
摘要翻译： 本发明涉及用于将抗原递送至免疫反应性靶细胞的碳氟载体。 它还涉及碳氟载体 - 抗原构建体以及与抗原相关的这种载体作为动物疫苗和免疫治疗剂的用途。
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公开(公告)号：US06993947B2
公开(公告)日：2006-02-07
申请号：US10416895
申请日：2001-11-14
申请人： Fabrice Tondo , Jacques-Yves Bourgon , Dominique Bonnet , Christophe Noardo , Gilbert Petig , Pierre Vienot
发明人： Fabrice Tondo , Jacques-Yves Bourgon , Dominique Bonnet , Christophe Noardo , Gilbert Petig , Pierre Vienot
IPC分类号： B21D1/02
摘要： A metal measurement plate (5), having a size suitable for being placed between the set of upper rolls and the set of lower rolls of the leveler, has positioning means (60, 61, 62) for positioning it with respect to the rolls in the leveling direction, and strain gauges (51) for measuring elastic deformations of the plate during clamping on the leveler, said strain gauges being fastened to the plate so as to form several transverse rows of gauges (51 to 56) each located vertically in line with one of said rolls, on the opposite face of the plate with respect to said roll.
摘要翻译： 具有适合放置在整套上辊和整平机的一组下辊之间的尺寸的金属测量板（5）具有用于相对于辊定位的定位装置（60,61,62） 平整方向和应变计（51），用于测量在平整机上夹紧期间板的弹性变形，所述应变片紧固到板上，以便形成几排横向排的量规（51至56） 与所述辊中的一个相对于所述辊在所述板的相对面上。
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公开(公告)号：US20100183708A1
公开(公告)日：2010-07-22
申请号：US12700566
申请日：2010-02-04
CPC分类号： A61K47/48023 , A61K31/02 , A61K38/02 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K47/54 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/5555 , A61K2039/55566 , A61K2039/60 , A61K2039/6018 , C07C19/08 , C07C57/52 , C07K2/00 , C07K14/005 , C12N7/00 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
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公开(公告)号：US08759281B2
公开(公告)日：2014-06-24
申请号：US13354871
申请日：2012-01-20
CPC分类号： A61K47/48023 , A61K31/02 , A61K38/02 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K47/54 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/5555 , A61K2039/55566 , A61K2039/60 , A61K2039/6018 , C07C19/08 , C07C57/52 , C07K2/00 , C07K14/005 , C12N7/00 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
摘要翻译： 本发明涉及用于将抗原递送至免疫反应性靶细胞的碳氟载体。 它还涉及碳氟载体 - 抗原构建体以及与抗原相关的这种载体作为动物疫苗和免疫治疗剂的用途。
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公开(公告)号：US20120315293A1
公开(公告)日：2012-12-13
申请号：US13354871
申请日：2012-01-20
CPC分类号： A61K47/48023 , A61K31/02 , A61K38/02 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K47/54 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/5555 , A61K2039/55566 , A61K2039/60 , A61K2039/6018 , C07C19/08 , C07C57/52 , C07K2/00 , C07K14/005 , C12N7/00 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
摘要翻译： 本发明涉及用于将抗原递送至免疫反应性靶细胞的碳氟载体。 它还涉及碳氟载体 - 抗原构建体以及与抗原相关的这种载体作为动物疫苗和免疫治疗剂的用途。
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公开(公告)号：US07687455B2
公开(公告)日：2010-03-30
申请号：US11096725
申请日：2005-04-01
CPC分类号： A61K47/48023 , A61K31/02 , A61K38/02 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K47/54 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/5555 , A61K2039/55566 , A61K2039/60 , A61K2039/6018 , C07C19/08 , C07C57/52 , C07K2/00 , C07K14/005 , C12N7/00 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
摘要翻译： 本发明涉及用于将抗原递送至免疫反应性靶细胞的碳氟载体。 它还涉及碳氟载体 - 抗原构建体以及与抗原相关的这种载体作为动物疫苗和免疫治疗剂的用途。
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公开(公告)号：US20090170749A1
公开(公告)日：2009-07-02
申请号：US12086591
申请日：2006-12-15
申请人： Marcel Hibert , Hadjila Chabane , Dominique Bonnet , Jacques Haiech , Francois Renault-Mihara , Hervé M. Chneiweiss
发明人： Marcel Hibert , Hadjila Chabane , Dominique Bonnet , Jacques Haiech , Francois Renault-Mihara , Hervé M. Chneiweiss
CPC分类号： G01N33/582 , A61K38/00 , C07K5/06078
摘要： The present invention relates to novel pseudopeptide compounds of defined formula, capable of interacting with the PEA-15 protein and to the use thereof in screening methods and to a method of diagnosing pathological conditions which may involve PEA-15.
摘要翻译： 本发明涉及能够与PEA-15蛋白相互作用的定义式的新型拟肽化合物及其在筛选方法中的应用以及诊断可能涉及PEA-15的病理状况的方法。
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公开(公告)号：US08110540B2
公开(公告)日：2012-02-07
申请号：US12700526
申请日：2010-02-04
CPC分类号： A61K47/48023 , A61K31/02 , A61K38/02 , A61K39/00 , A61K39/12 , A61K39/21 , A61K39/385 , A61K47/54 , A61K2039/54 , A61K2039/543 , A61K2039/545 , A61K2039/55511 , A61K2039/5555 , A61K2039/55566 , A61K2039/60 , A61K2039/6018 , C07C19/08 , C07C57/52 , C07K2/00 , C07K14/005 , C12N7/00 , C12N2740/16022 , C12N2740/16034 , C12N2740/16122 , C12N2740/16134 , C12N2740/16322
摘要： The present invention relates to fluorocarbon vectors for the delivery of antigens to immunoresponsive target cells. It further relates to fluorocarbon vector-antigen constructs and the use of such vectors associated with antigens as vaccines and immunotherapeutics in animals.
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