-
1.发明申请公开(公告)号：US20100081934A1
公开(公告)日：2010-04-01
申请号：US12629775
申请日：2009-12-02
申请人： Azita Soltani , Douglas R. Hansmann
发明人： Azita Soltani , Douglas R. Hansmann
CPC分类号： A61N7/00 , A61B17/2202 , A61B2017/22001 , A61M37/0092 , A61N2007/0039 , A61N2007/0043
摘要： In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.
摘要翻译： 在本发明的一个实施方案中，治疗位于患者脉管系统内的治疗部位的血管闭塞的方法包括将超声导管定位在治疗部位。 该方法还包括在第一处理阶段期间将微泡治疗化合物从超声导管输送到血管闭塞。 该方法还包括在微泡治疗化合物的递送保持暂停期间，暂停微泡治疗化合物的递送并将超声能量从超声导管输送到第二治疗阶段期间的血管闭塞。
-
公开(公告)号：US06979293B2
公开(公告)日：2005-12-27
申请号：US10320847
申请日：2002-12-16
CPC分类号： A61B17/22012 , A61B2017/00057 , A61B2017/00084 , A61B2017/00101 , A61B2017/22021 , A61B2017/22082 , A61B2017/22084
摘要： A method for monitoring a clot dissolution treatment in a patient's vasculature comprises positioning a catheter at a treatment site in the patient's vasculature. The method further comprises performing a clot dissolution treatment at the treatment site. The clot dissolution treatment comprises delivering ultrasonic energy and a therapeutic compound from the catheter to the treatment site such that a clot located at the treatment site at least partially dissolves. The method further comprises delivering a thermal measurement signal from a first portion of the catheter to the treatment site during the clot dissolution treatment. The method further comprises receiving the thermal measurement signal at a second portion of the catheter. The method further comprises comparing the delivered thermal measurement signal with the received thermal measurement signal to evaluate a blood flow rate at the treatment site.
摘要翻译： 用于监测患者脉管系统中的凝块溶解治疗的方法包括将导管定位在患者脉管系统的治疗部位。 该方法还包括在治疗部位进行凝块溶解处理。 凝块溶解处理包括将超声能量和治疗化合物从导管输送到治疗部位，使得位于治疗部位的血块至少部分溶解。 该方法还包括在凝块溶解治疗期间将热测量信号从导管的第一部分输送到治疗部位。 该方法还包括在导管的第二部分处接收热测量信号。 该方法还包括比较传送的热测量信号与接收的热测量信号，以评估处理部位的血液流速。
-
公开(公告)号：US20120289889A1
公开(公告)日：2012-11-15
申请号：US13468920
申请日：2012-05-10
IPC分类号： A61M37/00
摘要： A catheter system for delivering ultrasonic energy to a treatment site within a body lumen, the catheter comprises a tubular body having a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end and a plurality of ultrasound radiating members in the energy delivery section. The plurality of ultrasound radiating members are allocated into electrical groups comprising more than one ultrasound radiating member. Members of one electrical group are spatially interdigitated with members of another electrical group.
摘要翻译： 一种用于将超声能量输送到体腔内的治疗部位的导管系统，所述导管包括管状体，所述管状体具有近端，远端和位于所述近端和远端之间的能量输送部分，以及多个超声辐射 能源交付部门的成员。 多个超声波辐射构件被分配成包括多于一个的超声波辐射构件的电组。 一个电气组的成员与另一个电气组的成员在空间上相互交错。
-
公开(公告)号：US08226629B1
公开(公告)日：2012-07-24
申请号：US12415965
申请日：2009-03-31
IPC分类号： A61M31/00
CPC分类号： A61M37/0092 , A61B17/320068
摘要： A method of treating an occlusion at a treatment site within a patient's vasculature comprises providing an ultrasonic catheter. The ultrasonic catheter has a distal region, a proximal region opposite the distal region, a fluid delivery lumen having at least one opening in the distal region, and an ultrasound radiating member positioned within the distal region. The method further comprises positioning the ultrasonic catheter at the treatment site, such that at least a portion of the distal region is within the occlusion. The ultrasonic catheter further comprises passing a therapeutic compound through the fluid delivery lumen such that the therapeutic compound is delivered to the treatment site. The ultrasonic catheter further comprises emitting ultrasonic energy from the ultrasound radiating member. The emitted ultrasonic energy has an amplitude that is periodically varied between a low amplitude and a high amplitude.
摘要翻译： 治疗患者脉管系统内的治疗部位的闭塞的方法包括提供超声导管。 超声波导管具有远端区域，与远端区域相对的近端区域，具有在远侧区域中的至少一个开口的流体输送腔和位于远侧区域内的超声波辐射构件。 该方法还包括将超声波导管定位在治疗部位，使得远侧区域的至少一部分在咬合内。 超声波导管还包括使治疗化合物通过流体输送腔，使得治疗化合物被递送至治疗部位。 超声波导管还包括从超声波辐射构件发射超声波能量。 发射的超声能量具有在低振幅和高振幅之间周期性变化的幅度。
-
公开(公告)号：US07201737B2
公开(公告)日：2007-04-10
申请号：US11046209
申请日：2005-01-28
申请人： Douglas R. Hansmann , Peter R. Rule
发明人： Douglas R. Hansmann , Peter R. Rule
IPC分类号： A61F7/12
CPC分类号： A61B17/2202 , A61B2018/046
摘要： A method for providing a therapeutic effect to a treatment site within a patient's vasculature comprises positioning a catheter at the treatment site. The catheter includes a heating element and a fluid delivery lumen that is coupled to an exit port within a distal region of the catheter. The method further comprises passing the therapeutic compound through the delivery lumen and the exit port at a flow rate. The heated therapeutic compound is provided to the treatment site. The method further comprises exposing at least a portion of the treatment site and at least a portion of the delivered heated therapeutic compound to ultrasonic energy generated by the ultrasound radiating member.
摘要翻译： 用于向患者的脉管系统内的治疗部位提供治疗效果的方法包括将导管定位在治疗部位。 导管包括加热元件和流体输送腔，其与导管的远侧区域内的出口连接。 该方法还包括以流速使治疗化合物通过输送腔和出口。 将加热的治疗化合物提供给治疗部位。 所述方法还包括将所述处理部位的至少一部分和所递送的加热治疗化合物的至少一部分暴露于由所述超声波辐射部件产生的超声波能量。
-
公开(公告)号：US11458290B2
公开(公告)日：2022-10-04
申请号：US13468920
申请日：2012-05-10
摘要： A catheter system for delivering ultrasonic energy to a treatment site within a body lumen, the catheter comprises a tubular body having a proximal end, a distal end and an energy delivery section positioned between the proximal end and the distal end and a plurality of ultrasound radiating members in the energy delivery section. The plurality of ultrasound radiating members are allocated into electrical groups comprising more than one ultrasound radiating member. Members of one electrical group are spatially interdigitated with members of another electrical group.
-
公开(公告)号：US07993308B2
公开(公告)日：2011-08-09
申请号：US11046052
申请日：2005-01-28
IPC分类号： A61M25/00
CPC分类号： B08B9/00 , A61B17/2202 , A61B90/70 , A61B2090/701 , A61M2025/0019 , B08B9/043 , B08B2209/005
摘要： A central venous catheter comprises an ultrasound assembly. In one arrangement, the radiating member is used to remove a blockage from the central venous catheter. In another arrangement, inserting an ultrasound assembly into a central venous catheter. The ultrasound assembly comprises an ultrasound radiating member mounted on an elongate support structure. The method further comprises positioning the ultrasound assembly within the central venous catheter such that the ultrasound radiating member is adjacent to a deposited material formed on a portion of the central venous catheter. The method further comprises supplying an electrical current to the ultrasound radiating member to expose the deposited material to ultrasonic energy. The method further comprises passing a therapeutic compound through the central venous catheter to expose the deposited material to the therapeutic compound simultaneously with ultrasonic energy.
摘要翻译： 中心静脉导管包括超声组件。 在一种布置中，辐射构件用于从中心静脉导管移除堵塞物。 在另一种布置中，将超声组件插入中心静脉导管中。 超声组件包括安装在细长支撑结构上的超声辐射构件。 该方法还包括将超声组件定位在中心静脉导管内，使得超声辐射构件与形成在中心静脉导管的一部分上的沉积材料相邻。 该方法还包括向超声辐射构件提供电流以将沉积的材料暴露于超声波能量。 该方法还包括使治疗化合物通过中心静脉导管，以同时用超声能量将沉积的材料暴露于治疗化合物。
-
8.发明授权公开(公告)号：US07648478B2
公开(公告)日：2010-01-19
申请号：US12046375
申请日：2008-03-11
申请人： Azita Soltani , Douglas R. Hansmann
发明人： Azita Soltani , Douglas R. Hansmann
IPC分类号： A61B17/20
CPC分类号： A61N7/00 , A61B17/2202 , A61B2017/22001 , A61M37/0092 , A61N2007/0039 , A61N2007/0043
摘要： In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.
摘要翻译： 在本发明的一个实施方案中，治疗位于患者脉管系统内的治疗部位的血管闭塞的方法包括将超声导管定位在治疗部位。 该方法还包括在第一处理阶段期间将微泡治疗化合物从超声导管输送到血管闭塞。 该方法还包括在微泡治疗化合物的递送保持暂停期间，暂停微泡治疗化合物的递送并将超声能量从超声导管输送到第二治疗阶段期间的血管闭塞。
-
9.发明申请公开(公告)号：US20080208109A1
公开(公告)日：2008-08-28
申请号：US12046375
申请日：2008-03-11
申请人： Azita Soltani , Douglas R. Hansmann
发明人： Azita Soltani , Douglas R. Hansmann
IPC分类号： A61M37/00
CPC分类号： A61N7/00 , A61B17/2202 , A61B2017/22001 , A61M37/0092 , A61N2007/0039 , A61N2007/0043
摘要： In one embodiment of the present invention, a method of treating a vascular occlusion located at a treatment site within a patient's vasculature comprises positioning an ultrasound catheter at the treatment site. The method further comprises delivering a microbubble therapeutic compound from the ultrasound catheter to the vascular occlusion during a first treatment phase. The method further comprises pausing the delivery of the microbubble therapeutic compound and delivering ultrasonic energy from the ultrasound catheter to the vascular occlusion during a second treatment phase while the delivery of microbubble therapeutic compound remains paused.
摘要翻译： 在本发明的一个实施方案中，治疗位于患者脉管系统内的治疗部位的血管闭塞的方法包括将超声导管定位在治疗部位。 该方法还包括在第一处理阶段期间将微泡治疗化合物从超声导管输送到血管闭塞。 该方法还包括在微泡治疗化合物的递送保持暂停期间，暂停微泡治疗化合物的递送并将超声能量从超声导管输送到第二治疗阶段期间的血管闭塞。
-
公开(公告)号：US6135976A
公开(公告)日：2000-10-24
申请号：US161063
申请日：1998-09-25
CPC分类号： A61M37/0092 , A61K41/0028 , A61K47/48992 , A61M2025/0057 , A61M2025/105 , A61M2025/1086 , A61M25/1011
摘要： A catheter is provided for performing gene therapy on a selected section of a body lumen. The catheter comprises a distal catheter body including one or more expandable members for occluding sections of the body lumen proximal and/or distal to the selected section of the body lumen; a gene therapy composition delivery lumen connected to one or more gene therapy composition delivery ports at the distal catheter body for delivering a gene therapy composition to the selected section of the body lumen, the gene therapy composition delivery lumen housing a gene therapy agent; a washing lumen connected to one or more washing ports for delivering fluid to wash the selected section of the body lumen; and an ultrasound transducer for delivering ultrasound energy to the selected section of the body lumen.
摘要翻译： 提供用于在体腔的选定部分进行基因治疗的导管。 所述导管包括远侧导管主体，所述远端导管主体包括一个或多个可扩张构件，用于闭塞所述体腔的位于所述体腔的所述选定部分的近侧和/或远侧的部分; 基因治疗组合物递送腔，其连接到远侧导管体处的一个或多个基因治疗组合物递送端口，用于将基因治疗组合物递送至体腔的选定部分，所述基因治疗组合物递送腔容纳基因治疗剂; 洗涤管腔，连接到一个或多个清洗口，用于输送流体以洗涤体腔的选定部分; 以及用于将超声能量输送到所述体腔的所选部分的超声换能器。
-
-
-
-
-
-
-
-
-
搜索结果
17 条记录 (耗时 0.019 秒)
