Needleless catheters and methods for true lumen re-entry in treatment of chronic total occlusions and other disorders
    1.
    发明授权
    Needleless catheters and methods for true lumen re-entry in treatment of chronic total occlusions and other disorders 有权
    无针导管和真空管腔重新进入治疗慢性完全闭塞和其他疾病的方法

    公开(公告)号:US08374680B2

    公开(公告)日:2013-02-12

    申请号:US12106689

    申请日:2008-04-21

    Inventor: Dustin Thompson

    Abstract: A catheter system comprising a) an elongate flexible catheter; b) a lumen that extends from a proximal insertion port to a side outlet opening; c) a penetrating guidewire insertable into the proximal insertion port and thereafter advanceable through the lumen and out of the side outlet opening; and d) an orientation element useable to provide an indication of the trajectory on which the penetrating guidewire will advance from the catheter body. Also disclosed are methods for using such catheter to direct the penetrating guidewire out of the side opening and into the true lumen of a blood vessel when bypassing an obstruction in the blood vessel such as a chronic total occlusion (CTO) of an artery.

    Abstract translation: 一种导管系统,包括:a)细长柔性导管; b)从近端插入口延伸到侧出口的内腔; c)穿透导丝,其可插入到所述近端插入口中,然后可以通过所述内腔并从所述侧出口开出; 以及d)可用于提供所述穿透导丝将从导管主体前进的轨迹的指示的定向元件。 还公开了当绕过血管阻塞物(例如动脉的慢性完全闭塞(CTO))时,使用这种导管将穿透导线引导出侧开口并进入血管的真腔的方法。

    Obstruction removal system
    2.
    发明授权
    Obstruction removal system 失效
    阻塞消除系统

    公开(公告)号:US08021380B2

    公开(公告)日:2011-09-20

    申请号:US11972744

    申请日:2008-01-11

    Abstract: An obstruction removal system for percutaneous removal of clots or obstructions within the vascular system is disclosed. The obstruction removal system includes a multi-lumen catheter with a plurality of circulating capture devices attached to or integral with a drive belt. The circulating capture or interference devices affect removal of the clot or obstruction bit-by-bit through a series of passes. The obstruction removal system may include one or more drive mechanisms, such as a pulley system and/or a vacuum source and/or a pressurization source, on its proximal end for driving the drive belt and capture devices through the catheter in a circulating manner. The obstruction removal system may also include one or more cleaning mechanisms, such as a vacuum chamber and/or a fluid rinse chamber, for removing the captured clot pieces from the capture devices.

    Abstract translation: 公开了一种用于经皮去除血管系统内的血块或障碍物的阻塞去除系统。 阻塞去除系统包括多腔导管,其具有附接到驱动带或与传动带一体的多个循环捕获装置。 循环捕获或干扰装置通过一系列通路影响凝块的清除或逐位阻塞。 障碍物移除系统可以在其近端包括一个或多个驱动机构,例如皮带轮系统和/或真空源和/或加压源,用于驱动驱动带并以循环方式通过导管捕获装置。 阻塞去除系统还可以包括一个或多个清洁机构,例如真空室和/或流体冲洗室,用于从捕获装置移除捕获的凝块。

    One-Way valve Prosthesis for Percutaneous Placement Within the Venous System
    5.
    发明申请
    One-Way valve Prosthesis for Percutaneous Placement Within the Venous System 审中-公开
    静脉系统中经皮置入的单向瓣膜假体

    公开(公告)号:US20100131049A1

    公开(公告)日:2010-05-27

    申请号:US12276866

    申请日:2008-11-24

    Abstract: A one-way valve prosthesis for percutaneous placement within a vein, the valve including a valve body having an inlet and an outlet with a lumen that extends there between. The valve body is operable to alternate between a closed configuration wherein the valve body has a double cone shape and an open configuration wherein the valve body has a double frustoconical shape. A valve seat if formed within the lumen of the valve body at a midsection thereof. The valve seat is constricted to prevent flow there through when the valve body is in the closed configuration and the valve seat is open to allow flow there through when the valve body is in the open configuration. The valve seat opens in response to an actuation pressure and closes in the absence of the actuation pressure.

    Abstract translation: 一种用于在静脉内经皮放置的单向瓣膜假体,所述瓣膜包括具有入口的阀体和具有在其间延伸的内腔的出口。 阀体可操作以在闭合构型之间交替,其中阀体具有双锥形形状和打开结构,其中阀体具有双截头圆锥形状。 如果在阀体的中部形成在阀体的内腔内的阀座。 当阀体处于关闭状态并且阀座处于打开状态时,阀座处于收缩状态,以防止流过其中,从而当阀体处于打开状态时允许其流过。 阀座响应于致动压力而打开,并且在没有致动压力的情况下关闭。

    Devices and Methods for Controlled-Depth Injection
    6.
    发明申请
    Devices and Methods for Controlled-Depth Injection 审中-公开
    受控深度注射的装置和方法

    公开(公告)号:US20090270806A1

    公开(公告)日:2009-10-29

    申请号:US12108961

    申请日:2008-04-24

    Abstract: Devices and methods for limiting the depth to which a penetrator is advanced into an organ or mass of tissue. The device generally comprises a first member and a second member. The penetrator is attached to and extends from a second member. The first member has a penetrator shroud and a hollow bore extending therethrough. The second member is engageable with the first member such that a distal portion of the penetrator extends through the penetrator shroud. The distance to which the penetrator protrudes out of and beyond the distal end of the penetrator shroud is adjustable in accordance with the desired depth of penetration. The penetrator may then be advanced into the organ or tissue mass until the distal end of the shroud abuts against the organ or tissue mass, thereby stopping further advancement of the penetrator. The penetrator may have one or more lumen(s) for aspirating or infusing substances.

    Abstract translation: 用于限制穿透器进入器官或组织块的深度的装置和方法。 该装置通常包括第一构件和第二构件。 穿透器附接到第二构件并从第二构件延伸。 第一构件具有穿透器护罩和延伸穿过其中的中空孔。 第二构件可与第一构件接合,使得穿透器的远端部分延伸穿过穿透器护罩。 穿透器突出到穿透器护罩的远端之外的距离可以根据期望的穿透深度进行调节。 然后穿透器可以推进到器官或组织块中,直到护罩的远端抵靠器官或组织块,从而停止穿透器的进一步前进。 穿透器可以具有用于吸入或输注物质的一个或多个内腔。

    Obstruction Removal System
    7.
    发明申请
    Obstruction Removal System 失效
    阻塞移除系统

    公开(公告)号:US20090182362A1

    公开(公告)日:2009-07-16

    申请号:US11972744

    申请日:2008-01-11

    Abstract: An obstruction removal system for percutaneous removal of clots or obstructions within the vascular system is disclosed. The obstruction removal system includes a multi-lumen catheter with a plurality of circulating capture devices attached to or integral with a drive belt. The circulating capture or interference devices affect removal of the clot or obstruction bit-by-bit through a series of passes. The obstruction removal system may include one or more drive mechanisms, such as a pulley system and/or a vacuum source and/or a pressurization source, on its proximal end for driving the drive belt and capture devices through the catheter in a circulating manner. The obstruction removal system may also include one or more cleaning mechanisms, such as a vacuum chamber and/or a fluid rinse chamber, for removing the captured clot pieces from the capture devices.

    Abstract translation: 公开了一种用于经皮去除血管系统内的血块或障碍物的阻塞去除系统。 阻塞去除系统包括多腔导管,其具有附接到驱动带或与传动带一体的多个循环捕获装置。 循环捕获或干扰装置通过一系列通路影响凝块的清除或逐位阻塞。 障碍物移除系统可以在其近端包括一个或多个驱动机构,例如皮带轮系统和/或真空源和/或加压源,用于驱动驱动带并以循环方式通过导管捕获装置。 阻塞去除系统还可以包括一个或多个清洁机构,例如真空室和/或流体冲洗室,用于从捕获装置移除捕获的凝块。

    Hollow drug-filled stent and method of forming hollow drug-filled stent
    8.
    发明授权
    Hollow drug-filled stent and method of forming hollow drug-filled stent 有权
    空心药物填充支架和形成中空药物填充支架的方法

    公开(公告)号:US08998977B2

    公开(公告)日:2015-04-07

    申请号:US13447004

    申请日:2012-04-13

    Abstract: A stent is formed from a wire having an outer member, a radiopaque member lining at least a portion of the outer member inner surface, and a lumen defined by the outer member inner surface or the radiopaque member inner surface. A substance is disposed in the lumen to be eluted through at least one opening disposed through the outer member to the lumen. The radiopaque member may be substantially continuous along the length of the wire or disposed only along portions of the wire such as crowns. In a method for making the stent, a composite wire including an outer member, a radiopaque intermediate member, and a core member is shaped into a stent pattern and processed to remove the core member and optionally portions of the radiopaque intermediate member, without damaging the outer member.

    Abstract translation: 支架由具有外部构件的线材,内部至少部分外部构件内表面的不透射线构件以及由外部构件内表面或不透射线构件内表面限定的内腔形成。 物质被设置在内腔中以通过穿过外部构件设置到内腔的至少一个开口被洗脱。 不透射线的构件可以沿着导线的长度基本上是连续的,或者仅沿着线的部分如冠冠设置。 在制造支架的方法中,将包括外部构件,不透射线中间构件和芯构件的复合线材成形为支架图案并且被处理以移除芯构件以及可选地部分不透射线的中间构件,而不损坏 外部成员。

    HOLLOW DRUG-FILLED STENT AND METHOD OF FORMING HOLLOW DURG-FILLED STENT
    9.
    发明申请
    HOLLOW DRUG-FILLED STENT AND METHOD OF FORMING HOLLOW DURG-FILLED STENT 有权
    中空药液填充瓶和形成中空含氟钢瓶的方法

    公开(公告)号:US20130274867A1

    公开(公告)日:2013-10-17

    申请号:US13447004

    申请日:2012-04-13

    Abstract: A stent is formed from a wire having an outer member, a radiopaque member lining at least a portion of the outer member inner surface, and a lumen defined by the outer member inner surface or the radiopaque member inner surface. A substance is disposed in the lumen to be eluted through at least one opening disposed through the outer member to the lumen. The radiopaque member may be substantially continuous along the length of the wire or disposed only along portions of the wire such as crowns. In a method for making the stent, a composite wire including an outer member, a radiopaque intermediate member, and a core member is shaped into a stent pattern and processed to remove the core member and optionally portions of the radiopaque intermediate member, without damaging the outer member.

    Abstract translation: 支架由具有外部构件的线材,内部至少部分外部构件内表面的不透射线构件以及由外部构件内表面或不透射线构件内表面限定的内腔形成。 物质被设置在内腔中以通过穿过外部构件设置到内腔的至少一个开口被洗脱。 不透射线的构件可以沿着导线的长度基本上是连续的,或者仅沿着线的部分如冠冠设置。 在制造支架的方法中,将包括外部构件,不透射线中间构件和芯构件的复合线材成形为支架图案并且被处理以移除芯构件以及可选地部分不透射线的中间构件,而不损害 外部成员。

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